Leucocytosis in Febrile Seizure

Rajbhandari, Rateena; Aryal, Umesh Raj

doi:10.3126/jnps.v31i3.4577

Cited by 3 publications

(1 citation statement)

References 13 publications

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“…The incidence varies among different regions. In western Europe and USA the incidence is reported to be 2-5% whereas it is between 5-10% in India, 8.8% in Japan, 14% in Guam, 0.5-5% in China and 6.6% in [4][5][6] Nepal.…”

Section: Introductionmentioning

confidence: 99%

Use of Lumbar Puncture for First Episode of Febrile Seizure among Children 6 Months to 18 Months of Age: A Cross Sectional Study

Kayastha

Kumar

Karki

2018

Birat J. Health Sci.

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Introduction: Febrile seizure accounts for the majority cases of the pediatric seizure. Fever with seizure can be either due to febrile seizure or underlying serious infection as meningitis. As seizure may be the only manifestation of meningitis it is important to rule out meningitis in children presenting with fever and seizure.Objective: The objective of this study was to determine the incidence of meningitis among children aged 6 to 18 months presenting with first episode of febrile seizure.Methodology: A prospective observational study was conducted among 94 children with first episode of febrile seizure presenting to the emergency and observation wards of Kanti Childrens' Hospital and subjected to lumbar puncture (LP) as per the American Academy of Pediatrics (AAP) recommendations. The proportion of children with meningitis and no meningitis among the study population was determined, clinical characteristics were compared among these groups and the incidence of meningitis in simple febrile seizure and complex febrile seizure was calculated. The collected data was analysed using SPSS.Results: Twenty (21.3%) cases were diagnosed with meningitis among 94 children enrolled in our study. Meningitis was detected in 38.1% of the cases of complex febrile seizure and 7.7% of cases of simple febrile seizure. In the age group 6 to 12 months, 11 (17.4%) had meningitis while in 12 to 18 months of age, 9 (29%) were detected with meningitis. Meningitis was 7.38 times more likely in cases presenting with complex febrile seizure than simple febrile seizure (OR=7.58; 95% CI 2.24-24.4; p<0.001). Regarding the clinical characteristics, vomiting, fever of more than 48 hours duration prior to onset of seizure, impaired consciousness and complex features of seizure were found to be significantly associated with meningitis in our study.Conclusion: The probability of meningitis among children aged 6 to 18 months presenting with first episode of febrile seizure episode is high. In febrile convulsing children less than 18 months of age, meningitis should be considered even in the absence of signs of meningeal irritation. BJHS 2018;3(2)6:399-402.

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Section: Introductionmentioning

confidence: 99%

Use of Lumbar Puncture for First Episode of Febrile Seizure among Children 6 Months to 18 Months of Age: A Cross Sectional Study

Kayastha

Kumar

Karki

2018

Birat J. Health Sci.

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The baseline risk of multiple febrile seizures in the same febrile illness: a meta-analysis

et al. 2022

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Recurrence Risk of Febrile Seizures in Children

Rajbhandari

Shakya

Aryal

1970

J. Nepal Paedtr. Soc.

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Introduction: Febrile seizure is a common paediatric problem. Identifying children with febrile seizure who are at risk for recurrence is important so that special attention can be given to them. The objective of this study was to identify the risk factors for recurrence of febrile seizures in children. Materials and Methods: This was a prospective cohort study done at Kathmandu Medical College and Teaching Hospital, Kathmandu, Nepal. This study is a continuation of a previous study which looked at the leucocytosis in peripheral blood of children with febrile seizure. A detailed history including the risk factors for febrile seizure recurrence was obtained from the caregiver during follow up on subsequent days after discharge of children from the hospital who were previously admitted for febrile seizure. All children with febrile seizure belonging to age group of 6 months to 6 years were included in the study. Those with afebrile seizures or on anticonvulsants and those who refused to give consent were excluded. Each child was also examined and investigated for the cause of fever. Results: A total of 115 children with febrile seizure admitted for febrile seizure during the study period and all of them were followed up at outpatient department. Males accounted 62% and females 38%. Simple Febrile Seizures were seen in 80% of the cases and complex febrile seizures were seen in 20%. Out of all the cases 68(59%) had symptoms of viral prodrome. 59(51%) had recurrent febrile seizure. Low temperature at onset of Febrile Seizure (p=0.001), short duration of fever before onset of Febrile Seizure (0.026) and atypical Febrile Seizure (p=0.022) were the risk factors for recurrent febrile seizure. Conclusion: Febrile Seizure is a common paediatric problem commonly seen in males. Almost half of children with Febrile Seizure are at risk for recurrence in later date. The risk factors for these recurrences are modest rise in body temperature at the onset of febrile seizure, onset of seizure within 12 hours of fever and atypical presentation.

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Leucocytosis in Febrile Seizure

Cited by 3 publications

References 13 publications

Use of Lumbar Puncture for First Episode of Febrile Seizure among Children 6 Months to 18 Months of Age: A Cross Sectional Study

Use of Lumbar Puncture for First Episode of Febrile Seizure among Children 6 Months to 18 Months of Age: A Cross Sectional Study

The baseline risk of multiple febrile seizures in the same febrile illness: a meta-analysis

Recurrence Risk of Febrile Seizures in Children

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