Letter to the Editor: Very Late Reactivation of Retinopathy of Prematurity After Monotherapy With Intravitreal Bevacizumab

Mataftsi, Asimina; Koulali, Evangelia; Papageorgiou, Eleni; Ziakas, Nikolaos; Brazitikos, Periklis

doi:10.3928/23258160-20170428-01

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…All recurrences were treated with LPC. In addition to these criteria, additional LPC was performed for IVB-treated ROP patients to prevent late recurrence [18][19][20] when an avascular area remained before the patient's discharge or when the arrest of vascularization was accompanied by abnormal hyperpermeability observed through fluorescein angiography.…”

Section: Additional Laser Photocoagulationmentioning

confidence: 99%

Risk factors for myopia at 1-year corrected age following laser photocoagulation for retinopathy of prematurity

Mori

Arima

Ueda

et al. 2020

Eye

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Background/Objectives The prevalence of myopia is higher in preterm infants who underwent laser photocoagulation (LPC) for retinopathy of prematurity (ROP). The aim of this study was to investigate factors associated with myopia in preterm infants who undergo LPC for ROP. Subjects/Methods We retrospectively analysed the medical records of preterm infants born at Kyushu University Hospital (October 2008-March 2018) at ≤32 weeks of gestational age or with birth weight ≤1500 g. We evaluated the associations between nine clinical factors and the spherical equivalent at 1-year corrected age by performing multivariable linear regression in LPC-treated ROP patients. Results Among the 485 infants enroled, 76 developed ROP requiring treatment. Of these, 71 underwent LPC, which was provided to 63 infants as the primary treatment (LPC alone or the combination therapy of LPC and intravitreal injection of bevacizumab [IVB]) and to eight infants as additional LPC after IVB monotherapy. The results of a refractive examination at 1-year corrected age were available for 110 eyes of 56 infants (78.9%). The mean ± standard deviation of the SE value was −0.5 ± 3.0 dioptres (D). Multivariable linear regression analysis revealed a significant association between laser spot count and SE value (ß = −0.081 ± 0.040 D per 100 spots [mean ± standard error], p = 0.045). Conclusions Our results suggest that an increased laser spot count observed during ROP treatment associates with myopia.

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Section: Additional Laser Photocoagulationmentioning

confidence: 99%