Les huiles essentielles gagnent du terrain à l’officine

Couic-Marinier, Françoise; Lobstein, Annelise

doi:10.1016/j.actpha.2013.02.005

Cited by 5 publications

(5 citation statements)

References 1 publication

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“…Recently, people have returned to alternative medicine based on natural products due to its efficacy in the treatment and the prevention of diseases with negligible side effects. For example, the resistance of microbes to synthesized drugs is a new problem that has led to the use of plant derivatives [5]. The use of medicinal plants plays an important role in the health care system.…”

Section: Introductionmentioning

confidence: 99%

Chemical Profiling, Antioxidant, Antiproliferative, and Antibacterial Potentials of Chemically Characterized Extract of Citrullus colocynthis L. Seeds

Bourhia

Bouothmany

Bakrim³

et al. 2021

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Background: Citrullus colocynthis L. (C. colocynthis) is commonly known as colocynth. It belongs to the family Cucurbitaceae that is frequently used in alternative medicine in the north of Africa. The aim of the study: the present research was undertaken to investigate the chemical composition, antioxidant, antiproliferative, and antibacterial potentials of C. colocynthis seed extract. Material and methods: the chemical composition of C. colocynthis seed organic extract was characterized using gas chromatography/mass spectrometry (GC-MS). The antioxidant property was carried out using both β-carotene bleaching and DPPH assays. The antibacterial effect was effectuated using the agar disc diffusion method. The antiproliferative activity vs. human colorectal adenocarcinoma cell line (HT-29) and human breast adenocarcinoma cell line (MDA MB 231) were carried by WST-1 test. The chemical analysis showed the presence of interesting potentially bioactive compounds. The studied plant extract exhibited antioxidant potential with IC50 value of 2. 22 mg/mL (β-carotene bleaching) and 8.98 ± 0.619 mg/mL (DPPH). Concerning the antiproliferative activity, the seed extract was effective in MDA-MB-231 and HT-29 cancer cells with IC50 values 86.89 ± 3.395 and 242.1 ± 17.9 μg/mL, respectively, whilst the extract of Citrullus colocynthis seeds was non-toxic in healthy human dermal fibroblasts. Regarding the antibacterial test, the extract was effective in Gram-positive bacteria only. Conclusion: The outcome of this research indicated that the extracts from C. colocynthis seeds may compose a promising source with interesting compounds that can be used to fight cancer, free radicals damage, and bacterial infections.

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Section: Introductionmentioning

confidence: 99%

Chemical Profiling, Antioxidant, Antiproliferative, and Antibacterial Potentials of Chemically Characterized Extract of Citrullus colocynthis L. Seeds

Bourhia

Bouothmany

Bakrim³

et al. 2021

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“…In recent decades, people have returned to traditional medicine including natural products due to their effectiveness in treating and preventing diseases with fewer or no side effects. For instance, the resistance of bacteria to many developed antibiotics is a dilemma that has led to using natural products from medicinal plants with more positive effects compared to synthetic drugs [ 2 ]. For several decades, medicinal plants have played a key role in pharmacological research studies and drug development.…”

Section: Introductionmentioning

confidence: 99%

Phytochemical Identification, Acute, and Sub-Acute Oral Toxicity Studies of the Foliar Extract of Withania frutescens

et al. 2020

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Withania frutescens (W. frutescens) is a medicinal plant widely used to treat several diseases. This work aims to study phytochemical composition as well as acute and subacute toxicity of W. frutescens hydroethanolic extract in mice. The phytochemical composition of W. frutescens extract was performed using gas chromatographic analysis. Acute toxicity was studied in vivo with oral administration of single doses 400 mg/kg, 1000 mg/kg, and 2000 mg/kg for 14 days. Subacute toxicity was studied with the administration of repeated doses of 400 mg/kg/day and 2000 mg/kg/day for 28 days. Phytochemical analysis of W. frutescens hydro-ethanolic extract confirmed the presence of interesting chemical compounds. Acute toxicity results showed no toxic symptoms in mice treated with an increasing dose up to a maximum of 2000 mg/kg. Alongside acute toxicity, subacute data showed no clinical symptoms nor biochemical or histological alteration in mice treated with an increasing dose up to a maximum of 2000 mg/kg compared to the control group (p < 0.05). This study shows no toxic effects in animals treated with W. frutescens extract, and, therefore, this plant can be considered safe in animals up to 2000 mg/kg under both acute and subacute toxicity conditions.

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“…The effect of the final temperature, nitrogen flow rate and particle size on the performance of pyrolysis products were studied. The maximum yield of oil 45% by weight was obtained in the pyrolysis temperature of 550°C, with a flow rate of 1-300 cm 3 .min À1 sweep gas and the particle size of 0425 to 0850 mm [12,13].…”

Section: Introductionmentioning

confidence: 99%

Valorization of Forest Waste for the Production of Bio-oils for Biofuel and Biodiesel

Farissi¹

2023

Advances in Green Electronics Technologies in 2023

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Biomass is a renewable energy source to generate heat and electricity through the enhancement of various organic materials. Cistus slow pyrolysis of seeds and shells was carried out in a fixed bed reactor to determine the effect of pyrolysis temperature, heating rate, and particle size on the performance of pyrolysis. Therefore, pyrolysis experiments were performed at different temperatures, ranging from 300 to 500°C, with heating rates varying from 10 to 70°C.min−1 for shells and 7 to 28°C.min−1 for seeds. The particle sizes of samples range from 0.3 to 3.5 mm for shells and 0.075 to 1.2 mm for seeds. The highest yield of liquid products (53.31% for shells; 52.24% for seeds) was obtained at a pyrolysis temperature of 450°C and a heating rate of 40°C.min−1 for shells and 21°C.min−1 for seeds. The functional groups and chemical compounds present in the bio-oil obtained under optimal conditions were identified by FTIR. The calorific value of the bio-oil was equal to 37.05 and 37.93 MJ.kg−1 for shells and seeds, respectively. The obtained results show that the bio-oil from the pyrolysis of Cistus shells and seeds could be used as a renewable fuel or a source of pharmaceutical and chemical raw material.

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Les huiles essentielles gagnent du terrain à l’officine

Cited by 5 publications

References 1 publication

Chemical Profiling, Antioxidant, Antiproliferative, and Antibacterial Potentials of Chemically Characterized Extract of Citrullus colocynthis L. Seeds

Chemical Profiling, Antioxidant, Antiproliferative, and Antibacterial Potentials of Chemically Characterized Extract of Citrullus colocynthis L. Seeds

Phytochemical Identification, Acute, and Sub-Acute Oral Toxicity Studies of the Foliar Extract of Withania frutescens

Valorization of Forest Waste for the Production of Bio-oils for Biofuel and Biodiesel

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