Les effets indésirables receveurs inconnus de cinq régions françaises : analyse, résultats, propositions

Aullen, J.-P.; Delbosc, Anaïs; Cœur, F. Ferrer Le; Rivière, Philippe; Schlanger, S.

doi:10.1016/j.tracli.2009.11.002

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“…Post-transfusion purpura is one of the rare immunologic reactions found in patients receiving multiple transfusions [1]. The use of non-leukocyte-depleted blood products increases the frequency of post transfusion event and exposes alloimmunization platelet [2].…”

Section: Introductionmentioning

confidence: 99%

Clinical Case: About a Probable Case of Post-Transfusion Purpura in a Homozygous Sickle Cell

Irène¹,

Jocia²,

Sonia³

et al. 2017

CRCM

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Alloimmunization to platelet antigens exposes to a serious immunological incident. We report a probable case of a post-transfusion purpura from homozygous sickle cell child alloimmunized against platelet antigen. We detail the challenges of alloantibody identification and transfusion management. These challenges are due to the lack of laboratory techniques for typing HLA and HPA system and the use of leukocyte-depleted (filtered) blood products.

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Section: Introductionmentioning

confidence: 99%