2003
DOI: 10.1590/s1413-86702003000300003 View full text |Buy / Rent full text
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Abstract: Leptospirosis is an acute anthropo-zoonotic infection of worldwide significance caused by spirochaete Leptospira interrogans which has 23 serogroups and >200 serovars. Various factors influencing the animal activity, suitability of the environment for the survival of the organism and behavorial and occupational habits of human beings can be the determinants of incidence and prevalence of the disease. The disease was considered inconsequential till recently, but it is emerging as an important public health prob… Show more

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“…Among these animals, rodents present a particular in Brazil under such conditions due to their transmission of leptospirosis. Three species with distinct ecological niches are present (Rattus norvegicus, R. rattus, and Mus musculus), but all adapt readily to different environmental conditions, have high reproductive rates and are associated with several human diseases (Rao et al 2003;Silva et al 2003). Rodents are usually associated with dirt, disease, and death, and their extermination is, thus, needed.…”
Section: Introductionmentioning
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“…Among these animals, rodents present a particular in Brazil under such conditions due to their transmission of leptospirosis. Three species with distinct ecological niches are present (Rattus norvegicus, R. rattus, and Mus musculus), but all adapt readily to different environmental conditions, have high reproductive rates and are associated with several human diseases (Rao et al 2003;Silva et al 2003). Rodents are usually associated with dirt, disease, and death, and their extermination is, thus, needed.…”
Section: Introductionmentioning
“…Reactions persist for months or years. Therefore, persistent antibodies allow retrospective diagnosis [36]. In that moment, due to the lower probability of leptospires detection in blood, serologic methods become required [37].…”
Section: Serological Diagnosis (Indirect Methods)mentioning
“…The titer will rise in a second specimen taken after 3 to 7 d. If the titer remains below 100 even on repeated testing, it may be assumed that it was due to the previous leptospirosis and not to current illness. A titre of 400 to 800 or more or a 4-fold rise in titer between 2 tests (between sera taken five to 10 d), is diagnostic when combined with a clinical illness compatible with leptospirosis [36,3].…”
Section: Interpretation Of Diagnostic Matmentioning
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