Leptin gene polymorphism (rs7799039; G2548A) is associated with changes in serum lipid concentrations during pregnancy: a prospective cohort study

Leptin gene polymorphism (rs 7799039;G2548A) is associated with changes in lipid profile during a partial meal‐replacement hypocaloric diet

“…After 8 weeks of treatment, Plantago ovata consumption lowered the plasma cholesterol concentrations to a greater extent in non‐A allele carriers compared to non‐A allele carriers. In another prospective cohort of pregnant females, the AA genotype reported a higher energy intake (higher fat) and a higher increase in triglyceride concentrations during pregnancy than females without the A allele ( 21 ) . In our study, non‐A allele carriers have a greater decrease in LDL‐cholesterol and triglyceride levels than non‐A allele carriers despite having the same significant weight loss.…”