Leprosy: Social implications from antiquity to the present

Grzybowski, Andrzej; Sak, Jarosław; Pawlikowski, Jakub; Nita, Małgorzata

doi:10.1016/j.clindermatol.2015.10.009

Cited by 23 publications

(20 citation statements)

References 11 publications

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“…This observation raises the question of how leprosy might have led to reduced reproductive fitness given that affected people, at least in modern populations, rarely die from the disease. Leprosy patients in the Middle Ages had to endure rejection and isolation in leprosaria and were not allowed to marry 23 . In addition, leprosy is known today to result in a hormone-related decrease in fertility 24 , 25 and a higher vulnerability to other infections 26 – 29 .…”

Section: Discussionmentioning

confidence: 99%

Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans

et al. 2018

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Leprosy, a chronic infectious disease caused by Mycobacterium leprae (M. leprae), was very common in Europe till the 16th century. Here, we perform an ancient DNA study on medieval skeletons from Denmark that show lesions specific for lepromatous leprosy (LL). First, we test the remains for M. leprae DNA to confirm the infection status of the individuals and to assess the bacterial diversity. We assemble 10 complete M. leprae genomes that all differ from each other. Second, we evaluate whether the human leukocyte antigen allele DRB1*15:01, a strong LL susceptibility factor in modern populations, also predisposed medieval Europeans to the disease. The comparison of genotype data from 69 M. leprae DNA-positive LL cases with those from contemporary and medieval controls reveals a statistically significant association in both instances. In addition, we observe that DRB1*15:01 co-occurs with DQB1*06:02 on a haplotype that is a strong risk factor for inflammatory diseases today.

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Section: Discussionmentioning

confidence: 99%

Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans

et al. 2018

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“…Tujuan dari program ini adalah untuk meningkatkan kesadaran di masyarakat dan penyedia layanan kesehatan (Muthuvel et al, 2017). Masyarakat umum harus sadar bahwa kusta bukanlah kelainan genetik dan 100% dapat disembuhkan (Grzybowski, Sak, Pawlikowski, & Nita, 2016). Meningkatkan kesadaran masyarakat tentang penyembuhan dari kusta dapat memotivasi pasien kusta untuk menunjukkan perilaku adaptif dengan mengadopsi mekanisme koping yang lebih baik.…”

Section: Program Kesadaran Sosial (Social Awareness)unclassified

Mekanisme dan Strategi Mengurangi Stress pada Pasien Kusta

Jatimi

Nenobais

Jufriyanto

et al. 2020

Indonesian J. Community Health Nurs.

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Introduction: Leprosy is an infectious disease that still causes very complex problems. The problem is not only from the medical, physical and psychological aspects of the sufferer but it also extends to social problems such as the community acceptance of people affected by leprosy, culture and the economy related to income sources and employmentMethod: We searched for articles within the following databases: Scopus, Google Scholar, Science Direct, PubMed and Proquest. Fifteen articles were reviewed. There are 6 coping strategies in leprosy patients that affect stress including reading books, social awareness programs, stigma, acceptance, social support and knowledge.Result: From the results of the analysis, these can be applied to provide support for people affected by leprosy to change their coping mechanisms to allow them to be more adaptive.Conclusion: These strategies need to be considered to determine the level of coping of an individual in dealing with stress stimulation in patients with leprosy originating from themselves, others and the environment.

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“…Also, in programs to handle leprosy, the spiritual factor, which is so important, is often overlooked and the focus is only on detection and treatment so that the programs for handling leprosy do not run well. The care of leprosy patients involves various aspects: after the person is physically healthy again, treatment must be continued, sometimes for a long time, to treat the person psychologically and emotionally [ 14 ]. According to Hatzenbuehler et al [ 15 ], a stigma is any kind of physical and social attribute which lowers the self-esteem and social acceptance of a person in some way including physically, socially, sexually, and/or ethnically [ 16 ] (Kumar, 2001).…”

Section: Literature Reviewmentioning

confidence: 99%

Effectiveness of Traditional Healers in Program to Control Leprosy in Nagan Raya District in Aceh

Alamsyah¹,

Usman

Yusuf³

et al. 2018

Dermatology Research and Practice

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Aceh Province had the highest rate of leprosy in Indonesia; in 2014, 436 new Multibacillary cases were reported. Nagan Raya was the District in Aceh with the highest number of cases; new cases in 2015 comprised 26 with Paucibacillary (PB) and 21 with Multibacillary (MB) with a total of 4.26% with Grade II disability. The phenomena of handling and treatment by the people in Nagan Raya involve treatment by traditional healers, “Tabib”, to treat the leprosy, with treatments known as Peundang locally. The purpose of this study was to find out and to take steps to improve the effectiveness of the Tabib in controlling leprosy in Nagan Raya. The main object of this study, which used a quasi-experimental design, was to find out and to improve the treatment of leprosy patients by the Tabib who treat them there. Data was gathered using a questionnaire with an interview and the intervention was to provide training and a pocket book about leprosy and how to detect, control, and manage it there and the role that the Tabib can play in controlling leprosy in the future. The results of the study showed that there was a significant difference in knowledge about leprosy between the EG (Experimental Group) Tabib after they got the training including the pocket book and the Tabib in the Control Group (CG); i.e., that did not get any training nor the pocket book. Furthermore, after the training, there was also a significant difference in the attitude towards leprosy between the EG and the CG of Tabib. There was also a significant difference in the future role of the Tabibs to control the spread of leprosy between the EG and the CG. Based on these results, it is hoped that the District Health Department can implement a partnership model with the Tabib in Nagan Raya (and elsewhere) to use the pocket book with training to implement a program to control the spread of leprosy and also to always support the Tabib to improve their role in controlling and eliminating leprosy amongst the village people.

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Leprosy: Social implications from antiquity to the present

Cited by 23 publications

References 11 publications

Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans

Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans

Mekanisme dan Strategi Mengurangi Stress pada Pasien Kusta

Effectiveness of Traditional Healers in Program to Control Leprosy in Nagan Raya District in Aceh

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