Introduction: Maca (Lepidium meyenii) belongs to the Brassicaceae family and it grows in Peru´s central Andes above 4000 and 4500 meters of altitude from the sea level. The plant belongs to the brassica (mustard) family and the Lepidium genus. Its closest relatives are rapeseed, mustard, turnip, and cabbage. Maca has multiple clinical applications like proactive against cancer, libido maintenance, menopause, and fertility. There are several mechanisms the Maca could impact at fertility problems.The increase of Luteinizing hormone (LH), increase the semen quality and improve sexual development in male, and at female, increases the libido and improve menopause symptoms with a possible influence at germ cell quality.