Lentoids within sacrococcygeal teratoma: Origin by transdifferentiation?

Jurić-Lekić, Gordana; Trosić, A; Švajger, Anton

doi:10.1016/0046-8177(93)90305-z

Cited by 4 publications

(1 citation statement)

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“…In the present ovarian teratoma, histological features of those aberrant teratoma components, which were lined by a combination of two different types of epithelial cells (keratinizing/non-keratinizing stratified squamous epithelial cells and cuboidal/ columnar epithelial cells) were reminiscent of those in transdifferentiation, dedifferentiation, or simple squamous metaplasia. The phenomenon of transdifferentiation is suggested to have played a role in sacrococcygeal teratoma in human beings (Jurić-Lekić et al, 1993). Identification of dedifferentiation is documented in an ovarian teratoma (Yasunaga et al, 2011) and other teratomas involving internal visceral organs or tissues in human beings (Game et al, 2001;Kim et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

Ovarian teratoma displaying a wide variety of tissue components in a broiler chicken (<i>Gallus Domesticus</i>): morphological heterogeneity of pluripotential germ cell during tumorigenesis

Ohfuji¹

2016

Open Vet J.

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Spontaneous ovarian teratoma was found in a seven-week-old female Chunky broiler chicken that was slaughtered for food. On post-mortem inspection, a spherical tumor mass attaching to a juvenile ovary was found in the abdominal cavity. Histopathologically, the tumor was comprised of immature mesenchymal stroma and a variety of mature tissue elements of mesodermal and ectodermal origin. In addition, there were multiple indistinguishable tissue elements, which showed no malignant cytological features but were unidentifiable as to corresponding embryological layer of origin. These heterogeneous teratoma tissues consisted of a variety of glandular, cystic, duct-like, and tubular structures, some of which exhibited a lining by a mixture of both keratinizing/non-keratinizing stratified squamous epithelial cells and cuboidal/columnar epithelial cells. The ovarian tetatoma was considered a benign and congenital one. The highly diverse differentiation of the teratoma might have manifested a morphological aspect of intrinsic character of the pluripotential germ cells during tumorigenesis.

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Section: Introductionmentioning

confidence: 99%

Ovarian teratoma displaying a wide variety of tissue components in a broiler chicken (<i>Gallus Domesticus</i>): morphological heterogeneity of pluripotential germ cell during tumorigenesis

Ohfuji¹

2016

Open Vet J.

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Huge Fetal Sacrococcygeal Teratoma with a Completely Formed Eye and Intratumoral DNA Ploidy Heterogeneity

et al. 1999

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Preterm infants and newborns with sacrococcygeal teratomas are at high risk for prenatal and perinatal complications. The prognosis depends on size and histology of the tumor, degree of prematurity, associated malformations, route of delivery, and prompt and complete surgical removal. Virtually any tissue can be present in a sacrococcygeal teratoma, but to date, ocular lens has been documented only as lentinoids (lens-like cells), whereas flow-cytometric data have been variably interpreted. We describe a case of a sacrococcygeal teratoma in an infant of 29 weeks gestational age that is remarkable for the weight (4500 g), the presence of a completely formed eye, and intratumoral DNA ploidy heterogeneity.

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The Cellular and Molecular Bases of Vertebrate Lens Regeneration

Henry

2003

International Review of Cytology

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Lentoids within sacrococcygeal teratoma: Origin by transdifferentiation?

Cited by 4 publications

References 9 publications

Ovarian teratoma displaying a wide variety of tissue components in a broiler chicken (<i>Gallus Domesticus</i>): morphological heterogeneity of pluripotential germ cell during tumorigenesis

Ovarian teratoma displaying a wide variety of tissue components in a broiler chicken (<i>Gallus Domesticus</i>): morphological heterogeneity of pluripotential germ cell during tumorigenesis

Huge Fetal Sacrococcygeal Teratoma with a Completely Formed Eye and Intratumoral DNA Ploidy Heterogeneity

The Cellular and Molecular Bases of Vertebrate Lens Regeneration

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