Lemierre's syndrome with fourth nerve palsy

Lee, Seongmu; Rutar, Tina; Velez, Federico G.; Rosenbaum, Arthur L.

doi:10.1016/j.jaapos.2008.08.004

Cited by 9 publications

(8 citation statements)

References 7 publications

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“…However, most cases are bilateral. 15 Nevertheless, we hypothesize that the increased intracranial pressure was asymmetric, causing left eye mild proptosis, vision loss, and nerve dysfunction (thus the greater optic disc edema and left eye RAPD). Lemierre's syndrome, a potentially grave and life-threatening disease, characterized by a septic thrombophlebitis of the internal jugular vein after acute oropharyngeal infection and subsequent disseminated septic embolization, 15 was ruled out since our patient did not develop fever throughout the entire hospitalization period, white blood cell count and inflammatory parameters were normal, and blood cultures were negative.…”

Section: Discussionmentioning

confidence: 96%

Bilateral papilledema and abducens nerve palsy following cerebral venous sinus thrombosis due to Gradenigo's syndrome in a pediatric patient

Costa

João

Guimarães

2020

American Journal of Ophthalmology Case Reports

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Purpose To report a case of bilateral papilledema and abducens nerve palsy following cerebral venous sinus thrombosis in a 9-year-old female with undiagnosed Gradenigo's Syndrome. Observations The patient presented to our Emergency Room with a unilateral left 6th nerve palsy, left eye relative afferent pupillary defect, and bilateral papilledema. She underwent cranial magnetic resonance imaging with gadolinium contrast and magnetic resonance venography, which diagnosed a left mastoiditis, left sigmoid sinus and jugular vein thrombosis. The patient underwent urgent mastoidectomy and myringotomy with tube placement and was admitted for adequate treatment with intravenous antibiotics and anticoagulants. Conclusions and importance Gradenigo's syndrome is a rare complication of otitis media, and even rarer is cerebral venous thrombosis. This potentially life-threatening situation requires immediate surgical and antibiotic therapy. Ocular symptoms can be the initial signs of this illness.

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Section: Discussionmentioning

confidence: 96%

Bilateral papilledema and abducens nerve palsy following cerebral venous sinus thrombosis due to Gradenigo's syndrome in a pediatric patient

Costa

João

Guimarães

2020

American Journal of Ophthalmology Case Reports

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“…There are reports of isolated fourth and sixth nerve palsies resulting from Lemierre's syndrome [18,19].…”

Section: Discussionmentioning

confidence: 99%

Lemierre's Syndrome: A Case Report with Fatal CNS Complications

Zee¹

2016

Clin Med Img Lib

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“…Infection-induced nerve palsies usually develop either from direct extension through the facial plane between the tonsils and the parapharyngeal space or by hematogenous or lymphatic spread from peritonsillar vessels. 4 Cases of oculomotor nerve palsy, 8 trochlear nerve palsy, 9 and multiple nerve palsies 7 associated with Lemierre's syndrome have been described in both children and adults. Abducens nerve palsy associated with Lemierre's syndrome has been reported to occur in adults.…”

Section: Discussionmentioning

confidence: 99%