Leishmaniose visceral em cães de assentamentos rurais

Silva, José D.; Melo, Demmya Haryssam Menezes; Costa, José A.G.; Costa, Diego Figueiredo da; Silva, Raizza Barros Sousa; Melo, Márcia Almeida de; Azevêdo, Sérgio Santos de; Alves, Clebert José

doi:10.1590/s0100-736x2017001100016

Cited by 20 publications

(30 citation statements)

References 28 publications

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“…Alguns ambientes que apresentam características ambientais e socioculturais que propiciam ambientes favoráveis para a manutenção do mosquito como ambientes em moradias próximos de matas (SILVA et al, 2016;SILVA et al, 2017), o que pode explicar os animais soropositivos da região de Uberlândia (MG), pois os animais assistidos no abrigo são animais errantes, provenientes de abandonos em área rural e urbana, onde previamente o animal entrou em contato com o vetor flebotomíneo. De acordo com Monteiro et al (2005), as transformações ambientais como urbanização e êxodo rural, acarretam a expansão e o aparecimento de novos focos e facilitada a ocorrência de epidemias.…”

Section: Methodsunclassified

Prevalência De Leishmaniose Canina Em Cães De Abrigo No Municipio De Uberlãndia – Minas Gerais – Estudo De Caso

Reis¹,

Andrade²,

Teixeira³

et al. 2020

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RESUMO A leishmaniose é um grande problema atualmente na saúde pública global e é uma doença endêmica em várias regiões do Brasil e do mundo, causada por protozoários do gênero Leishmania, sendo que as principais espécies que causam a leishmaniose visceral em cães são a Leishmania infantum e L. chagasi, que são disseminadas pela picada do mosquito flebotomíneo. Os maiores reservatórios da leishmaniose visceral são os cães domésticos. O aumento do número de cães abandonados em abrigo tem aumentado bastante, e o risco de disseminação de doenças entre esses animais em abrigo tornou-se constante. O presente estudo teve como objetivo avaliar a prevalência da leishmaniose em cães de abrigo no município de Uberlândia, Minas Gerais. Foram selecionados 39 cães no abrigo da Associação Protetora de Animais (APA) e diagnosticados pelo teste triagem ALERE® Leishmania, sendo identificados dois animais soropositivos. Os mesmos foram também reagentes positivos ao teste confirmatório ELISA, sendo considerados doentes. A prevalência aparente observada foi de 5,12% (IC 95%: 1,42-16,89) e a identificação de casos confirmados da leishmaniose canina é útil para detectar áreas de riscos, e assim tomar medidas preventivas e de promoção em saúde.

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Section: Methodsunclassified

Prevalência De Leishmaniose Canina Em Cães De Abrigo No Municipio De Uberlãndia – Minas Gerais – Estudo De Caso

Reis¹,

Andrade²,

Teixeira³

et al. 2020

Enci Bio

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“…A zoonose pode relacionar-se com regiões de florestas remanescentes que foram modificadas, sendo os espaços rurais importantes locais de armazenamento para concentração de vetores e reservatórios (SILVA, 2017). Dessa forma, os assentamentos de reforma agrária pertencentes aos municípios que compõem a Região de Saúde de Presidente Prudente -SP poderiam enquadrar-se como importantes focos para dispersão da doença na região.…”

Section: A Formação Profissional Para Atençãounclassified

Formação Profissional para Atenção Básica e Conhecimento Geográfico

2019

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Visceral Leishmaniasis (VL) can be related to remnant regions of modified forests and rural spaces tend to store vectors and reservoirs. This study aimed to evaluate the epidemiological situation of VL in municipalities that support agrarian reform settlements, belonging to the Health Region of Presidente Prudente, São Paulo, and to establish relationship with the existence of surveillance and control measures for the disease. The municipalities studied were classified according to the structure of the zoonoses service and epidemiological situation, applying spatial analysis and cartographic information treatment. The data collection of strategies for the prevention and control of Canine Visceral Leishmaniasis (CVL) and its periodicity (continuous actions, punctual or without actions) occurred through an online questionnaire, which could be answered by professionals responsible for the Program of Control of Vectors/Zoonoses of their municipalities. Of 45 municipalities, 19 (42.2%) have a total of 121 settlements, facing different scenarios. The health surveillance for CVL carried out by the Unified Health System in the agrarian reform settlements of the study areas proved to be precarious and vulnerable. There was a close relationship between the availability and performance of the zoonoses team and the VL situation, especially in the silent municipalities (receptive or not).

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“…A leishmaniose visceral é uma zoonose de caráter crônico e fatal, sendo considerada um grave problema de saúde pública mundial [18,24,30]. É causada por protozoários do gênero Leishmania sp.…”

Section: Introductionunclassified

“…e a transmissão ocorre pela picada de flebotomíneos. Mamíferos podem ser acometidos, sendo o cão o principal reservatório [1,17,[23][24][25]27,30]. O animal infectado pode ser clinicamente saudável, mas é capaz de infectar o vetor e continuar com a disseminação [13].…”

Section: Introductionunclassified

“…O animal infectado pode ser clinicamente saudável, mas é capaz de infectar o vetor e continuar com a disseminação [13]. Os sinais clínicos incluem lesões cutâneas como alopecia, hiperqueratose nasal e úlceras, além de anorexia, onicogrifose e alterações oftálmicas [14,15,19,22,24,29,31]. Pode-se ainda observar febre, linfadenopatia, epistaxe e alterações oftálmicas e alterações laboratoriais como aumento das enzimas hepáticas e renais e diminuição de albumina sérica, além de anemia normocítica normocrómica [11,20,21,31].…”

Section: Introductionunclassified

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Use of Immunotherapy in the Treatment of Canine Visceral Leishmaniasis

Araújo¹,

Gondim²

2020

Acta Scientiae. Vet.

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Background: Canine visceral leishmaniasis is a worldwide zoonosis, with dogs being the main urban reservoirs. It is caused by a protozoan of the genus Leishmania spp. and is transmitted to mammals through a vector belonging to the phlebotomines family. Its treatment aims to reduce the parasitic load preventing these animals from being transmitters. Immunotherapy has been shown to be efficient in stimulating the patient's immune response, improving the general condition and preventing recurrence. This report describes the case of a dog diagnosed with canine visceral leishmaniasis submitted to immunotherapy and drug protocol, noting significant general improvement.Case: An 8-year-old female dog was treated with ulcerated lesions on the paw pads, nasal plane and lip region, onychogryphosis and ungeitis, in addition, hypertrophied popliteal lymph nodes and erosive lesions in the elbows, without improvement with previous treatments. Serological examination was then performed to diagnose leishmaniasis by the immunosorbent assay (ELISA) technique with negative results. In addition, was performed puncture of the popliteal lymph node, sample in which amastigote forms of Leishmania were observed and blood sample analysis by immunochromatographic rapid test showing reagent result, confirming the diagnosis of canine visceral leishmaniasis. The treatment protocol with marbofloxacin, allopurinol, prednisolone and domperidone was initiated. Thirty days later, there was a total improvement of the lesions and healing of the paw pads. Immunotherapy was then initiated by applying three double doses of recombinant vaccine against canine visceral leishmaniasis. The applications were made subcutaneously, with an interval of 21 days between them, still maintaining allopurinol. After six months a fourth double dose of the vaccine was applied and ten days later a new serological examination was performed using the Indirect Immunofluorescence Reaction (IIFR) technique with total dilution, with the result not reagent. Four months later, the patient was reevaluated and a new serological test was performed through the IIFR technique with total dilution and the result was reagent with high titration (1: 320). Then began the use of milteforan and domperidone. After two months, the patient received a new vaccination booster and the use of domperidone was discontinued. After ten days a new serological examination was performed using the IIIRF technique with total dilution, with reagent result, but with minimal titration (1:40).Discussion: Canine visceral leishmaniasis is a systemic zoonosis of major public health importance. The dog, due to its proximity to humans, is considered the main reservoir of the disease. Although clinical signs are nonspecific, skin lesions such as nasal hyperkeratosis, ulcers and hyperpigmentation, as well as clinical manifestations such as lymphadenopathy, fever, epistaxis and ophthalmic changes are frequently observed. In this case, the patient presented most of the lesions described in the literature. Laboratory abnormalities in blood count and serum biochemistry, commonly observed, were not observed in the animal. The ELISA serological test, despite being used as a screening test, due to its ability to detect low antibody titers, was negative in this case. The diagnosis was confirmed by lymph node cytology, described in the literature as a confirmatory test despite being considered invasive by most authors and positive result in rapid immunochromatography test. With the protocol used, the animal showed improvement, being observed negative results or with low titration of anti-leishmania antibodies in a serological test performed using the IFAT technique, indicating a decrease in parasitic load.

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Leishmaniose visceral em cães de assentamentos rurais

Cited by 20 publications

References 28 publications

Prevalência De Leishmaniose Canina Em Cães De Abrigo No Municipio De Uberlãndia – Minas Gerais – Estudo De Caso

Prevalência De Leishmaniose Canina Em Cães De Abrigo No Municipio De Uberlãndia – Minas Gerais – Estudo De Caso

Formação Profissional para Atenção Básica e Conhecimento Geográfico

Use of Immunotherapy in the Treatment of Canine Visceral Leishmaniasis

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