Leishmaniasis of glans penis

Schubach, Armando de Oliveira; Cuzzi-Maya, Tullia; Gonçalves-Costa, S. C.; Pirmez, Claude; Oliveira-Neto, Manoel P.

doi:10.1016/s0926-9959(98)00013-0

Cited by 18 publications

(18 citation statements)

References 8 publications

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“…There are few published cases of leishmaniasis located in the genital area, settling down in most of them that the lesions are due to direct inoculation of the parasite 4,9,13 . Some authors suggest that the genital localization can result of the possible blood dissemination in those patients 10 .…”

Section: Discussionmentioning

confidence: 99%

Leishmaniasis in the genital area

Cabello

Caraballo

Millán

2002

Rev. Inst. Med. trop. S. Paulo

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Two patients from the gold mines of Bolivar State, Venezuela, presenting cutaneous leishmaniasis in the genital region, an unusual location, are described. The first patient showed an ulcerated lesion of the glans penis. Leishmanin skin test was positive. A biopsy specimen revealed a granulomatous infiltrate containing Leishmania parasites. In the second patient, Leishmanin skin test was positive, HIV and VDRL were negative. Leishmania parasites were present in a biopsy of an ulcerated lesion in the scrotum, with an indurated base, infiltrative borders with an yellowish exudate. Patients were treated with meglumine antimoniate and the lesions healed.

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Section: Discussionmentioning

confidence: 99%

Leishmaniasis in the genital area

Cabello

Caraballo

Millán

2002

Rev. Inst. Med. trop. S. Paulo

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“…Spontaneous healing is virtually unknown. 8 Cutaneous lesions are commonly localized in uncovered areas of the body. Genital lesions are rare; leishmaniasis of the glans penis has been reported.…”

Section: Discussionmentioning

confidence: 99%

“…Genital lesions are rare; leishmaniasis of the glans penis has been reported. 8,9 Up to 40% of patients with sores caused by Leishmania braziliensis and a smaller proportion with sores caused by L. b. panamensis and L. b. guyanensis may develop mucosal lesions. Fifty percent of mucosal lesions develop within 2 years of appearance of skin lesions, and 90% within 10 years.…”

Section: Discussionmentioning

confidence: 99%

A chronic mutilating rhinopathy with a delayed diagnosis of mucocutaneous leishmaniasis

et al. 2010

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“…Infectious diseases are amongst the most frequent causes for male and female reproductive pathology and infertility, in humans and animals (Bennett, Dolin, & Blaser, ; Maxie, ). Reproductive tissue tropism has been studied in the context of Trichomonas (Parsonson, Clark, & Dufty, ) , T. gondii (Lopes et al, ; Stahl, Kaneda, Tanabe, & Kumar, ), T. cruzi (Id Boufker, Alexandre, Carlier, & Truyens, ), T. brucei (Carvalho et al, ), Plasmodium (Muehlenbein, Alger, Cogswell, James, & Krogstad, ; Raji, Akinsomisoye, & Azeez, ) , Entamoeba (reviewed in [Antony and Lopez‐Po ]) and to a large extend in Leishmania (Assis, Ribeiro, Rachid, Castro, & Valle, ; Blickstein, Dgani, & Lifschitz‐Mercer, ; Cabello, Caraballo, & Millan, ; Diniz et al, ; Gonzalez, Gallego, Castaño, & Rueda, ; Mir, Fontaine, Reyes‐Gomez, Carlus, & Fontbonne, ; Schubach, Cuzzi‐Maya, Gonçalves‐Costa, Pirmez, & Oliveira‐Neto, ). Infertility can be directly associated with presence of parasites in the tissue, through triggering inflammation and tissue damage or indirectly due to systemic effects that result in impaired reproductive function.…”

Section: Organs In the Abdominopelvic Cavitiesmentioning

confidence: 99%

Intravital imaging of host‐parasite interactions in organs of the thoracic and abdominopelvic cavities

Niz

Carvalho

Penha‐Gonçalves

et al. 2020

Cellular Microbiology

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Infections with protozoan and helminthic parasites affect multiple organs in the mammalian host. Imaging pathogens in their natural environment takes a more holistic view on biomedical aspects of parasitic infections. Here, we focus on selected organs of the thoracic and abdominopelvic cavities most commonly affected by parasites. Parasitic infections of these organs are often associated with severe medical complications or have health implications beyond the infected individual. Intravital imaging has provided a more dynamic picture of the host-parasite interplay and contributed not only to our understanding of the various disease pathologies, but has also provided fundamental insight into the biology of the parasites. K E Y W O R D S diseases, imaging, infection, intravital, microscopy, parasitology 1 | INTRODUCTION Most parasitic infections in mammals involve organs of the thoracic, abdominal and pelvic cavities, and may cause severe complications as a result of damage to these organs. Organs in the thoracic cavity include the heart, the lungs, the thymus, the thyroid and parathyroid.The heart is an important target of Trypanosoma cruzi; and the lungs, are key targets of multiple parasites causing a broad spectrum of pathology ranging from focal lesions to diffuse lung damage. In the abdominal cavity, organs include the stomach, the intestine, the liver, the gallbladder, the pancreas, the spleen, the kidneys, the adrenal glands and regional lymph nodes. In the pelvic cavity, the reproductive organs and the urinary bladder are harboured. All the above organs can be compromised by vector-borne and soil/water/food-borne parasites alike. Intravital microscopy (IVM) allows studying cellular and sub-cellular events within living animals, including host-pathogen interactions. In this review, we focus on key IVM-based findings on parasite biology in different organs of the thoracic and abdominopelvic cavities. Importantly, some of these organs pose specific challenges for visualisation. Here, we discuss the advances on surgical procedures, imaging platforms and image processing tools that have made visualisation of parasites within these organs possible. | ORGANS IN THE THORACIC CAVITYThe organs in the thoracic cavity most frequently affected by parasites are the lungs and heart (Figure 1a). The heart as the central organ of the circulatory system carries out vital functions by distributing blood, oxygen and nutrients to tissues and removing metabolic waste

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Leishmaniasis of glans penis

Cited by 18 publications

References 8 publications

Leishmaniasis in the genital area

Leishmaniasis in the genital area

A chronic mutilating rhinopathy with a delayed diagnosis of mucocutaneous leishmaniasis

Intravital imaging of host‐parasite interactions in organs of the thoracic and abdominopelvic cavities

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