Leiomyosarcoma of the vagina: a case report and review from the literature

Abstract

Leiomyosarcomas comprise fewer than 2% of all malignant vaginal neoplasms. Due to their rarity, treatment for vaginal leiomyosarcomas have not been determined. We describe a 66 year old woman with vaginal leiomyosarcoma, which presented as a large palpable mass with vaginal spotting. Complete surgical excision was accomplished and after surgery, she underwent radiation therapy. Tumor recurrence was not detected for the last 5 years and now her general condition is very good. This is a rare case of leiomyosarcoma arising in vagina and we report the results of successful treatment.

Primary vaginal sarcoma: Experience of a regional cancer center in China

“…There are various types of vaginal sarcoma. Leiomyosarcoma is the most common histology, comprising approximately two‐thirds of vaginal sarcoma cases . ESS, angiosarcoma, adenosarcoma and other histological types of sarcoma have also been reported .…”

Complete remission after abdominoperineal resection with posterior vaginectomy for repeated recurrent low-grade leiomyosarcoma of the vagina

“…Leiomyosarcoma accounts for only a small proportion of vaginal cancer and only about 140 cases have been reported in the literature [2,3,4]. There is no consensus on the treatment of vaginal leiomyosarcoma; wide surgical excision with or without radiotherapy is the most common treatment modality [2,5].…”

A large primary vaginal leiomyosarcoma diagnosed postoperatively and uterine leiomyomas treated with surgery and chemotherapy

“…Primary vaginal leiomyosarcomas comprise less than 2% of all malignant vaginal neoplasms (Suh and Park 2008). An extensive search of the literature disclosed 140 case reports published over the past 50 years.…”