Leiomyosarcoma of the Maxilla: A case report

Primary oral leiomyosarcoma: a clinico-pathologic study and analysis of prognostic factors

“…In contrast, primary LMS of the oral cavity is exceedingly rare, a finding attributed to the general paucity of smooth muscle in this location 9 . There have been about 65 cases reported in the English literature since 1950, often as individual case studies [1][2][3][4][5][7][8][9][10][12][13][14][16][17][18][19][20][21][22][23][24][25][26][27][28][30][31][32][33][34][35][36][37][38][39][40]42,43,45,47 . Diagnosis of these lesions can be difficult on routine histology alone, and earlier reports were frequently diagnosed without immunohistochemical confirmation [1][2][3]9,13,17,19,…”

Leiomyosarcoma of the buccal mucosa: a case report with immunohistochemistry findings

“…Sometimes, light microscopy with routine stains does not allow distinction of this sarcoma from others, especially when the cells are pleomorphic or if areas of nuclear palisading typical of schwannoma are observed. For this reason special stains, and above all immunohistochemistry, play a very important role in diagnosis (16). Early wide surgical excision with radical neck dissection for lymph node metastasis remains the mainstay of treatment (17).…”

Primary Leiomyosarcoma of the Oral Cavity: A Case Report and Review of the Literature

“…Leiomyosarcoma at other sites appears to be biologically different and has been divided into three main groups (1): retroperitoneal or intraabdominal, cutaneous or subcutaneous and, least common, those that arise from medium-to large-sized veins. Leiomyosarcoma is a rare neoplasm in the head and neck, and is particularly rare in the oral cavity, with only 71 previously reported cases of primary oral leiomyosarcoma (2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12). Of these, only nine occurred in the cheek (13).…”