Leiomyosarcoma of the Kidney

Ellouze, S.; Abid, N.; Kossentini, Mariem; Gouiaa, Naourez; Mhiri, N; Boudawara, T.

doi:10.1016/j.clgc.2011.05.001

Cited by 10 publications

(6 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…But small size (<5 cm), low histologic grade, absence of lymph node metastases and radical operations are all associated with better prognosis. Despite radical nephrectomy the tumors can run an aggressive clinical course and early local and distant recurrences are common (5). Renal leiomyosarcomas must be differentiated from epitheloid anjiomyolipoma, the sarcomatoid variant of renal cell carcinoma, fibrosarcoma and a malignant peripheral nerve sheath tumor (5).…”

Section: Discussionmentioning

confidence: 99%

“…Despite radical nephrectomy the tumors can run an aggressive clinical course and early local and distant recurrences are common (5). Renal leiomyosarcomas must be differentiated from epitheloid anjiomyolipoma, the sarcomatoid variant of renal cell carcinoma, fibrosarcoma and a malignant peripheral nerve sheath tumor (5). Retroperitoneal leiomyosarcoma secondarily involving the kidney must be ruled out before the diagnosing primary renal leiomyosarcoma (3).…”

Section: Discussionmentioning

confidence: 99%

“…Radical nephrectomy is the treatment choice for leiomyosarcoma of the kidney. Many urologists and oncologists have advocated radical nephrectomy followed by either chemotherapy or radiotherapy (5).…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Primary Leiomyosarcoma of the Kidney: Four Cases

Akkaya¹,

Tuncer²,

Akkaya³

et al. 2015

uob

View full text Add to dashboard Cite

Renal sarcomas are rare tumors. They constitute only %1-2 of malignant renal tumors in adulthood. Though leiomyosarcoma is the most common histologic type of renal sarcoma (%50-60) (1). Renal leiomyosarcomas are aggressive tumors arising from the renal capsule, renal vein, pelvic musculature or the renal parenchyma. Diagnosis is usually post-operative and requires a thorough sampling of the tumor to rule out an epithelial component (2). We report new four cases of primary renal leiomyosarcomas. Case Reports Case 1 Our first patient was a 61-year-old female. She was undergone radical nephrectomy. In the macroscopic examination, a wellcircumscribed, gray-white, swirl cut surface tumoral mass was seen in the lower pole of the kidney which causing renal pelvic and ureteral dilatation. The tumor sizes were measured 9.5x7.5x6 cm. In our microscopic examination, the tumor originated from

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Primary Leiomyosarcoma of the Kidney: Four Cases

Akkaya¹,

Tuncer²,

Akkaya³

et al. 2015

uob

View full text Add to dashboard Cite

show abstract

“…Treatment of leiomyosarcoma consists of radical nephrectomy. Surgery followed by chemotherapy and radiation has been advocated in the past with limited success [ 3 , 5 ]. Radical operations, size <5 cm, low histologic grade, and negative lymph node metastasis are all associated with a better prognosis [ 5 ].…”

Section: Discussionmentioning

confidence: 99%

Renal Leiomyosarcoma: A Diagnostic Challenge

Valery

Tan

Cortese

2013

Case Reports in Oncological Medicine

View full text Add to dashboard Cite

Renal leiomyosarcoma is a very rare tumor that clinically and radiographically mimics more common renal malignancies. The infrequency of the condition makes it very difficult to diagnose. A 70-year-old male smoker presented with months of hematuria, right-sided flank pain, and weight loss. Imaging revealed a 3.8-centimeter renal mass that had characteristics similar to renal cell carcinoma. Initial biopsy of the mass was negative for malignancy. Two months later, subsequent imaging revealed what appeared to be metastatic bone lesions. Again, a biopsy of one of the lesions was negative for malignancy. Subsequent ureteral pyeloscopy, ureteroscopic renal pelvis biopsy, and brush cytology were negative for malignancy as well. The decision was made to perform nephrectomy for the removal of the mass. Pathologic analysis revealed renal leiomyosarcoma. This case illustrates the difficulty in diagnosing renal leiomyosarcoma. Repeated pathologic sampling was negative because of the tumor heterogeneity. Prompt diagnosis and treatment are very significant as surgical resection at an early stage offers the best prognosis.

show abstract

“…This is one of the few cases reported in the literature with metastatic activity related to the contralateral kidney. The focus is on the clinical picture, diagnostic imaging, immunohistochemical characteristics, surgical treatment, and follow-up at 6 months [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Primary leiomyosarcoma of kidney with metastasis to contralateral kidney. Case report

Ciriaco

Espinoza

Pedro³

2018

IMAS

View full text Add to dashboard Cite

IntroductionRenal leiomyosarcoma is a rare entity in the world and its understanding is based on reports and various cases; however, the prognosis is bleak for its malignant potential and an average survival of 18 months.Clinical caseA 54-year-old woman with a clinical picture of 6 months of pain in the right flank and a tomographic image of a bilateral renal lesion underwent right radical nephrectomy and left conservative surgery. The definitive histopathological study reported right primary renal leiomyosarcoma with left metastasis.ConclusionRenal leiomyosarcoma is an entity of low incidence and high mortality; however, our case represents the minority of patients with contralateral kidney metastasis reported in the literature.

show abstract

Leiomyosarcoma of the Kidney

Cited by 10 publications

References 8 publications

Primary Leiomyosarcoma of the Kidney: Four Cases

Primary Leiomyosarcoma of the Kidney: Four Cases

Renal Leiomyosarcoma: A Diagnostic Challenge

Primary leiomyosarcoma of kidney with metastasis to contralateral kidney. Case report

Contact Info

Product

Resources

About