Renal Leiomyosarcoma: A Diagnostic Challenge

Valery, Jose; Tan, Winston; Cortese, Cherise

doi:10.1155/2013/459282

Cited by 11 publications

(16 citation statements)

References 3 publications

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“…Deletions in the 4q31 and 18q22 regions have been associated with a high metastasis potential and the duplication at 1q21.3 has been identified as an independent prognostic factor for shorter survival times in patients with LMS. On the other hand, a 17q duplication is associated with a long-term disease-free survival and a low risk of metastasis and 1p33-p32.3 duplications were correlated with increased survival rates 3,38 .…”

Section: Genetic and Molecular Factorsmentioning

confidence: 99%

“…Valery et al found that a tumor size smaller than 5 cm is associated with a favorable prognosis 3 . In a study conducted by Hakan et al, 2 out of 10 patients enrolled in the research had a tumor measuring less than 5 cm, and they achieved the highest survival rate 25 .…”

Section: Anatomical and Surgical Factorsmentioning

confidence: 99%

“…Sarcomas typically possess a pseudocapsule, which is not a reliable barrier from the surgical point perspective, often being infiltrated by the tumor. Sarcomas of the kidney can expand and reach large sizes, due to the lack of natural barriers for tumors arising from the mesenchymal components 3 .…”

Section: Introductionmentioning

confidence: 99%

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Renal sarcoma – a rare parenchymal tumor with a very poor prognosis

Iorga¹,

Anghel²,

Marcu³

et al. 2018

Arch Balk Med Union

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Le sarcome rénal-une tumeur parenchymateuse rare avec un pronostic très mauvais Le but de cet article était d'analyser les caractéristiques pronostiques, la présentation clinique, le diagnostic et le traitement des sarcomes rénaux primaires. Une revue approfondie de la littérature a été réalisée à l'aide de la base de données PubMed. Les sarcomes du rein sont des tumeurs malignes très rares, avec un très mauvais pronostic par rapport aux autres sarcomes urogénitaux. Plusieurs types histologiques ont été rapportés, le type le plus courant étant le léiomyosarcome. Outre la résection chirurgicale complète à larges marges, des facteurs anatomiques, histologiques, moléculaires

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Section: Genetic and Molecular Factorsmentioning

confidence: 99%

Section: Anatomical and Surgical Factorsmentioning

confidence: 99%

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Renal sarcoma – a rare parenchymal tumor with a very poor prognosis

Iorga¹,

Anghel²,

Marcu³

et al. 2018

Arch Balk Med Union

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“…Sarcomas typically possess a pseudocapsule, which is often infiltrated by the tumor 3 . The documented biological behaviour of renal leiomyosarcoma is unpredictable which may be due to paucity of extensive literature.…”

Section: Introductionmentioning

confidence: 99%

Primary Renal Leiomyosarcoma: A Case Report

Singh¹

2018

jmscr

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“…Due to the lack of natural barriers for sarcomas arising from the mesenchymal components, renal sarcomas are able to expand and become large in size. Sarcomas typically possess a pseudocapsule, however, this represents an unreliable barrier and is often infiltrated by the tumor ( 3 ).…”

Section: Introductionmentioning

confidence: 99%

Prognostic features of renal sarcomas (Review)

Öztürk

2014

Oncology Letters

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The aim of the present review was to evaluate the prognostic features of primary sarcomas of the kidney. A literature review was conducted using a number of databases, including Medline (PubMed) and Scopus, for studies published between January 1992 and December 2013. Of the studies published in English, those describing the prognostic features of primary sarcomas of the kidney were recorded. The electronic search was limited to the following keywords: Sarcoma, renal sarcoma, prognosis, diagnosis, immunohistochemistry, genetic and survey. Subsequent to the search, no review articles and/or meta-analyses associated with the prognosis of primary sarcomas of the kidney were identified. In total, 31 studies, which consisted of case studies, case series and studies concerned with the overall prognosis of urological soft-tissue sarcomas, were reviewed. Primary sarcoma of the kidney has a poor prognosis compared with other sarcomas of the urogenital system. In addition to the surgical excision of renal sarcomas, pathological, molecular and genetic prognostic factors are also considered. Due to the small number of cases, previous studies have not randomized the prognostic features of primary sarcomas of the kidney. The elucidation of the so-called ‘chaotic’ genetic and molecular basis of renal sarcomas will help to predict patient prognoses. Surgical excision is the most significant parameter for determining the prognosis of sarcomas of the kidney. However, sarcomas also exhibit prognostic features that are based upon pathological, genetic and molecular factors. The present review suggests that additional factors may be important in predicting the prognosis of patients with renal sarcomas, and that clinicians should plan treatment and follow-up regimens according to these factors.

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Renal Leiomyosarcoma: A Diagnostic Challenge

Cited by 11 publications

References 3 publications

Renal sarcoma – a rare parenchymal tumor with a very poor prognosis

Renal sarcoma – a rare parenchymal tumor with a very poor prognosis

Primary Renal Leiomyosarcoma: A Case Report

Prognostic features of renal sarcomas (Review)

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