Legg-Calve-Perthes Disease

Kim, Harry K.W.

doi:10.1097/bpo.0b013e318223b4bd

Cited by 45 publications

(5 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The etiology of Legg-Calvé-Perthes disease remains enigmatic despite decades of research, but a key pathogenic event is disruption of the blood supply to the femoral head epiphysis [21] that—possibly combined with mechanical overload—causes aseptic osteonecrosis [2, 12, 32]. The incidence of Legg-Calvé-Perthes disease varies geographically and ranges from 0.5 per 100,000 in South Africa [45] to 21 per 100,000 in the Liverpool area [13], although a more recent survey indicates a declining incidence in Great Britain [40].…”

Section: Introductionmentioning

confidence: 99%

Is Legg-Calvé-Perthes Disease a Local Manifestation of a Systemic Condition?

Hailer¹,

Hailer²

2018

Clin Orthop Relat Res

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Is Legg-Calvé-Perthes Disease a Local Manifestation of a Systemic Condition?

Hailer¹,

Hailer²

2018

Clin Orthop Relat Res

View full text Add to dashboard Cite

show abstract

“…LCPD is an idiopathic condition that leads to variable avascular necrosis of the proximal femoral epiphysis in children [10] . Although the etiology, pathogenesis, and pathology of LPCD have not been completely elucidated, there are several known risk factors such as positive family history, low birth weight, abnormal birth presentation, secondary smoke inhalation, and ethnicity.…”

Section: Discussionmentioning

confidence: 99%

“…Although the etiology, pathogenesis, and pathology of LPCD have not been completely elucidated, there are several known risk factors such as positive family history, low birth weight, abnormal birth presentation, secondary smoke inhalation, and ethnicity. The prevailing view is that LCPD is a multifactorial disease caused by a combination of genetic and environmental factors [10] . In the current case, there is very little possibility that the development of LCPD was associated with the ipsilateral femoral shaft fracture resulting from high-energy trauma, because there were no associated risk factors for LCPD.…”

Section: Discussionmentioning

confidence: 99%

Legg–Calvé–Perthes disease following Ender nail fixation of a pediatric femoral fracture

Matsumura

Saito

Watanabe

et al. 2021

International Journal of Surgery Case Reports

View full text Add to dashboard Cite

Introduction and importance Legg–Calvé–Perthes disease (LCPD) sometimes occur in children, however it is difficult to diagnose it at the early stage especially in the cases there are no complaints of symptoms. Femoral shaft fractures in children cause various complications such as leg-length discrepancy, nonunion and malunion, refracture, and osteonecrosis of the femoral head. We presented a rare case in which a pediatric patient developed LCPD after femoral shaft fracture. Case presentation A healthy 8-year-old boy sustained a left femoral diaphyseal fracture following a pedestrian car accident. Fixation was achieved using retrograde Ender nails; bone union was confirmed at 3 months postoperatively, and the Ender nails were removed at 8 months postoperatively without any problems. Unfortunately, the morphological change of the ipsilateral femoral head and subtle symptoms were missed until the femoral head collapsed. LCPD was successfully treated with intertrochanteric varus osteotomy, which achieved a good clinical result. Clinical discussion Although the reason for the ipsilateral LCPD after the femoral shaft fracture is unclear, this case highlights the need for close postoperative follow-up of pediatric femoral fractures resulting from high-energy trauma to prevent the misdiagnosis of this coincidental complication. Conclusion This case report describes a missed ipsilateral LCPD after a femoral diaphyseal fracture caused by high-energy trauma. Close postoperative follow-up with a detailed assessment and vigilant interpretation of postoperative radiography is imperative to avoid delayed/missed diagnosis of conditions for which early management may provide better outcomes.

show abstract

“…Legg-Calve-Perthes Disease (LCPD) is a pediatric hip disorder that can lead to pain, deformity, and functional disability in adulthood [1][2][3][4][5][6]. The etiology of the disease is most likely due to vascular insufficiency [7][8][9], although the complete biological and mechanical mechanisms are not fully understood [10,11]. Both pelvic osteotomy and femoral osteotomy have been described for the treatment of LCPD [12].…”

Section: Introductionmentioning

confidence: 99%

Long-Term Outcomes at Skeletal Maturity of Combined Pelvic and Femoral Osteotomy for the Treatment of Legg–Calve–Perthes Disease

Regan,

Su,

Stans

et al. 2023

JCM

View full text Add to dashboard Cite

Surgical treatment for Legg–Calve–Perthes disease (LCPD) is recommended for older children with moderate to severe disease. We sought to determine whether double osteotomies lead to improved radiologic outcomes compared to reported non-operative outcomes. Patients older than 6 years of age diagnosed with LCPD lateral pillar B or C who were treated with pelvic and femoral osteotomies were included. Radiologic outcomes and leg-length discrepancies were assessed using the Stulberg classification and were compared with the current literature. Fifteen hips in fourteen patients were treated with double osteotomy for LCPD, and seven had lateral pillar C disease (47%). The mean age at surgery was 8.6 years (range, 7.2–10.4) and the mean age at follow-up was 20.2 years (range, 14.2–35.6). At a mean 11.6-year follow-up (range: 6.3–25.2), double osteotomy resulted in 40% of patients having Stulberg I/II scores, 27% having Stulberg III scores, and 33% having Stulberg IV/V scores. The mean leg-length discrepancy was 1.4 cm in lateral pillar C patients compared to 0.8 cm in lateral pillar B patients. Four patients underwent additional surgeries, including two who required total hip arthroplasty. Double osteotomy as an alternative surgical procedure for the treatment of LCPD did not show improved outcomes when compared to historic non-operative cohorts.

show abstract

Legg-Calve-Perthes Disease

Cited by 45 publications

References 42 publications

Is Legg-Calvé-Perthes Disease a Local Manifestation of a Systemic Condition?

Is Legg-Calvé-Perthes Disease a Local Manifestation of a Systemic Condition?

Legg–Calvé–Perthes disease following Ender nail fixation of a pediatric femoral fracture

Long-Term Outcomes at Skeletal Maturity of Combined Pelvic and Femoral Osteotomy for the Treatment of Legg–Calve–Perthes Disease

Contact Info

Product

Resources

About