Left-ventricular electromechanical delay is prolonged in patients with postoperative atrial fibrillation

Postoperative atrial fibrillation (POAF) is the most common complication after cardiac surgery, despite improvements in anesthesia, surgical techniques, and medical therapies. Although beta-blockers have been proven to be effective, the incidence of POAF is around 20 % even with these agents. The mechanism of POAF is not fully elucidated and no optimal strategy has been established for POAF. There are two important elements of "structural" and "electrical" remodelling of the atrium in the mechanism of POAF. A patient's age and preoperative left atrial fibrosis can predict POAF associated with structural remodelling. Although inflammation and oxidative stress during cardiac surgery may be the underlying mechanisms for electrical remodelling causing POAF, there are no reliable clinical parameters for their detection. Nonetheless, postoperative P-wave dispersion and electromechanical delay, which reflects excitation-contraction coupling abnormalities, could be new parameters for POAF. In conclusion, despite the importance of prevention of POAF, there are only a few parameters for predicting POAF. It is therefore necessary to consider both disease-mediated structural remodeling before surgery and electrical remodeling caused by cardiac surgery.

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Postoperative atrial fibrillation: mechanism, prevention, and future perspective

Shingu

Kubota

Wakasa

et al. 2012

Surg Today

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Real-time electro-mechanical profiling of dynamically beating human cardiac organoids by coupling resistive skins with microelectrode arrays

Yin,

Lees,

Gong

et al. 2025

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Pulse Arrival Time Segmentation Into Cardiac and Vascular Intervals – Implications for Pulse Wave Velocity and Blood Pressure Estimation

Beutel

Hoof

Rottenberg

et al. 2021

IEEE Trans. Biomed. Eng.

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Left-ventricular electromechanical delay is prolonged in patients with postoperative atrial fibrillation

Abstract: LVEMD is prolonged in patients with postoperative AF. This could be a new predicting parameter for AF in low-risk patients.

Cited by 4 publications

References 19 publications

Postoperative atrial fibrillation: mechanism, prevention, and future perspective

Postoperative atrial fibrillation: mechanism, prevention, and future perspective

Real-time electro-mechanical profiling of dynamically beating human cardiac organoids by coupling resistive skins with microelectrode arrays

Pulse Arrival Time Segmentation Into Cardiac and Vascular Intervals – Implications for Pulse Wave Velocity and Blood Pressure Estimation

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