Left-sided gastroschisis: higher incidence of extraintestinal congenital anomalies

Suver, Dan; Lee, Steven L.; Shekherdimian, Shant; Kim, Stephen S.

doi:10.1016/j.amjsurg.2007.12.042

Cited by 45 publications

(36 citation statements)

References 24 publications

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“…It is, however, very intriguing to note that left-sided cases are more often associated with extra digestive malforma- tions than the classical type [18] . Furthermore, at least the case reported by Shi et al [17] is clearly different from a gastroschisis, considering the defect was laterally located far from the absolutely normal base of the cord and left rectus muscle.…”

Section: Discussionmentioning

confidence: 97%

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Comprehensive Developmental Mechanisms in Gastroschisis

Bargy

Beaudoın²

2014

Fetal Diagn Ther

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Introduction: The development of gastroschisis remains an area of controversy. Various theories have been proposed, but none has ever been supported by a thorough embryological study. Material and Methods: We herein report anatomical and microscopic observations of the developing abdominal wall and cord of embryos and fetuses, along with clinical features of gastroschisis. Results: It appears that the developing cord normally has two parts, a firm left-sided part formed by the vessels and urachus, and a thin right-sided pouch covering the intestinal loops (the ‘physiological umbilical hernia'), which could rupture, giving the basis of gastroschisis. Discussion: Gastroschisis could be the result of amniotic damage, possibly from some as yet unidentified toxin. Further bowel damage can be explained by the subsequent mesenteric injury.

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Section: Discussionmentioning

confidence: 97%

“…The abdominal defect in gastroschisis is almost always right-sided, except for very few cases reported [16,17,18] . It is, however, very intriguing to note that left-sided cases are more often associated with extra digestive malforma- tions than the classical type [18] .…”

Section: Discussionmentioning

confidence: 99%

Comprehensive Developmental Mechanisms in Gastroschisis

Bargy

Beaudoın²

2014

Fetal Diagn Ther

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“…diskutiert werden [91]. Die Pathogenese könnte durch eine mögliche Rückbildungsstörung der rechten Umbilikalvene bedingt sein, dies würde auch einzelne Berichte [92][93][94][95][96] von linksseitigen Formen (linke Umbilikalvene) erklären. Eine genetische Komponente erscheint möglich [97], die abschließende Beurteilung steht noch aus.…”

Section: Gastroschisisunclassified

Was muss der (Viszeral-)Chirurg von der Kinderchirurgie wissen – kinderchirurgische Aspekte in der (Viszeral-)Chirurgie

Krause

Rißmann²,

Hj³

et al. 2011

Zentralbl Chir

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Due to the advances in neonatal intensive care medicine, prenatal ultrasound-guided diagnostic measures and paediatric surgical options, conditions have been established to achieve long-term survival in newborns with severe diseases. In addition, this means that the "non-paediatric" physician can be increasingly confronted with patients who would not have survived childhood some decades ago. Therefore, the article summarises concisely selected diseases of premature infants and newborns, e. g., congenital abdominal wall defects, and outlines possible long-term consequences based on the surgical interventions and their basic diseases, respectively, which need to be adequately cared for in the case of a surgical disease of the former patient of paediatric surgery. The overview cannot be considered as a complete revision course; however, it might constitute a basic outline for thought-provoking impulses for personal professional skills and expertise in managing such patients in later age from a surgical perspective.

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“…Associated anomalies are rare but intestinal atresia is present in up to 15% of cases. Review of literature suggests that the incidence of extra intestinal congenital anomalies is significantly higher in left-sided gastroschisis as compared to right sided gastroschisis [1][2][3][4]. Reported extra intestinal anomalies include choledochal cyst, cleft lip, cleft palate, pulmonary hypoplasia, atrial septal defect and patent ductus arteriosus, etc.…”

Section: Dear Sirmentioning

confidence: 99%