Left atrial systolic function is depressed in idiopathic and preserved in ischemic dilated cardiomyopathy

Triposkiadis, Filippos; Moyssakis, Ioannis; Hadjinikolaou, Leonidas; Makris, T.; Zioris, Harilaos; Hatzizaharias, A.; Kyriakidis, Michael

doi:10.1046/j.1365-2362.1999.00563.x

Cited by 45 publications

(34 citation statements)

References 44 publications

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“…In HF with reduced ejection fraction (HFrEF), LA emptying fraction has been shown to be significantly decreased 23. LA emptying fraction and LA strain are also reduced in HF with preserved ejection fraction (HFpEF) in clinical studies9, 24, 25 and randomized controlled trials [e.g.…”

Section: Prevalence Of Atrial Remodelling In Heart Failurementioning

confidence: 99%

Atrial remodelling in heart failure: recent developments and relevance for heart failure with preserved ejection fraction

et al. 2018

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Section: Prevalence Of Atrial Remodelling In Heart Failurementioning

confidence: 99%

Atrial remodelling in heart failure: recent developments and relevance for heart failure with preserved ejection fraction

et al. 2018

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“…LA and RA ejection fractions were calculated according to the formula (maximal volume -minimal volume)/ /maximal volume. LA and RA active emptying values were calculated as (volume at P-wave -minimal volume)/volume at P-wave [12][13][14].…”

Section: Atrial Mechanical Functionsmentioning

confidence: 99%

Impaired atrial electromechanical function and atrial fibrillation promotion in alloxan-induced diabetic rabbits

Fu¹,

Liu²,

Li³

et al. 2013

Cardiol J.

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“…[12][13][14] All values were obtained as the mean of three consecutive beats and were corrected for body surface area. Left atrial systolic (active emptying) function was assessed by use of the following parameters: [15][16][17][18] (1) Left atrial active emptying volume (ACTEV): left atrial volume at onset of atrial systole minus left atrial minimal volume; and (2) left atrial active emptying fraction (ACTEF): left atrial active emptying volume divided by the left atrial volume at onset of atrial systole.…”

Section: Echocardiographymentioning

confidence: 99%

Left atrial systolic function in primary and familial amyloidosis: Assessment from left atrial volume change

Moyssakis

Triposkiadis

Pantazopoulos

et al. 2004

Clinical Cardiology

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Summary:The severity of left ventricular involvement may differ between primary (PA) and familial amyloidosis (FA). This study examined whether differences in left atrial (LA) systolic function are also present. Twenty-eight patients (18 men, 10 women, aged 59 ± 12 years) with PA, 17 (11 men, 6 women, aged 40 ± 11 years) with FA, and 25 normal controls (18 men, 7 women, aged 56 ± 14 years) underwent transthoracic M-mode, two-dimensional, and Doppler echocardiography. Left atrial volumes were determined at mitral valve (MV) opening (maximal, Vmax), electrocardiographic P wave (onset of atrial systole, Vp), and MV closure (minimal, Vmin) from the apical two-and four-chamber views using the biplane area-length method. Left atrial systolic function was assessed with the LA active emptying volume (ACTEV) = Vp-Vmin and fraction (ACTEF) = ACTEV/Vp. The E/A ratio was increased (1.34 ± 0.93 vs. 0.89 ± 0.3), whereas deceleration time was decreased (168.1 ± 33.7 vs. 196.2 ± 34.2 ms) in PA compared with FA (p<0.05). Vmax and Vp were similar in PA and FA and greater than in the controls (46.6 ± 14 vs. 40 ± 11.4 vs. 27.1 ± 6.3 cm 3 /m 2 , p < 0.01, and 33.4 ± 11.6 vs. 29.7 ± 10.8 vs. 16.8 ± 3.8 cm 3 /m 2 , p < 0.01, respectively). The ACTEV was lower in PA and in the controls than in FA (6.7 ± 2 vs. 6.2 ± 2.2 vs. 8.5 ± 3.3, respectively, p < 0.05). The ACTEF was lower in PA than in FA and both were lower than those in the controls (20 ± 5% vs. 28 ± 7% vs. 36 ± 11%, respectively, p < 0.01). Despite a similar increase in LA volume, LA systolic dysfunction is more pronounced in PA than in FA. This is most likely due to the restrictive left ventricular physiology possibly associated with depressed LA contractility in the former.

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Left atrial systolic function is depressed in idiopathic and preserved in ischemic dilated cardiomyopathy

Cited by 45 publications

References 44 publications

Atrial remodelling in heart failure: recent developments and relevance for heart failure with preserved ejection fraction

Atrial remodelling in heart failure: recent developments and relevance for heart failure with preserved ejection fraction

Impaired atrial electromechanical function and atrial fibrillation promotion in alloxan-induced diabetic rabbits

Left atrial systolic function in primary and familial amyloidosis: Assessment from left atrial volume change

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