Left Atrial Size in Paroxysmal Atrial Fibrillation: Echocardiographic Evaluation and Follow-Up

Villecco, A.S.; Pilati, G.; Bianchi, Giampaolo; Zanardi, L

doi:10.1159/000174984

Cited by 18 publications

(2 citation statements)

References 15 publications

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“…Atrial chamber enlargement is a common finding in patients with chronic AF (8)(9)(10), and although the link between increased LA size and AF is widely recognized, it is not clear whether LA enlargement is the consequence or the cause of this arrhythmia (11)(12)(13). The relationship between LA enlargement and AF is somehow 'weaker' in LPAF patients.…”

Section: Discussionmentioning

confidence: 99%

Left atrial enlargement as a predictor of recurrences in lone paroxysmal atrial fibrillation

Zacà¹,

Galderisi²,

Mondillo³

et al. 2007

Canadian Journal of Cardiology

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Section: Discussionmentioning

confidence: 99%

Left atrial enlargement as a predictor of recurrences in lone paroxysmal atrial fibrillation

Zacà¹,

Galderisi²,

Mondillo³

et al. 2007

Canadian Journal of Cardiology

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“…As mentioned above, there is a relationship between increased LA size and AF. However, based on the results of several studies, it is not completely clear if the increase in LA size is the cause or the consequence of AF [47,48]. In our study population, increased LA size was identified as a predictor of AF.…”

Section: Discussionmentioning

confidence: 72%

Predictors of Higher Frequency of Atrial Fibrillation in Patients with Cardiac Resynchronization Therapy

Grbović,

Pavlović,

Žugić

2023

Medicina

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Background and Objectives: Cardiac resynchronization therapy (CRT) is one of the effective therapeutic options in the treatment of systolic heart failure (HF) with persistent symptoms. This prospective study was designed to determine whether CRT with biventricular pacing would reduce the risk of development of atrial fibrillation (AF) and to identify predictors for AF occurrence. Materials and Methods: The study population consisted of 126 patients, with a mean age of 63.8 ± 9.1 years, who were eligible for CRT with biventricular pacing. Inclusion criteria were left ventricular ejection fraction (LVEF) ≤ 35%, QRS duration ≥ 130 msec, and persistent HF symptoms of New York Heart Association (NYHA) II or III, despite optimal drug therapy. Patients were followed for a period of 24 months and were evaluated through clinical, electrocardiographic, and echocardiographic examination at baseline (prior to CRT implantation), as well as at 6 and 24 months post-implantation. At the end of follow-up, patients were divided into clinical responders and non-responders based on the following criteria: decrease in NYHA class ≥ I, increase in LVEF ≥ 10%, and reduction in QRS duration ≥ 20 msec. Results: At follow-up, CRT was associated with a significant increase in LVEF (20.6 ± 6.9% pre-implantation, 32.9 ± 9.3% 24 months after implantation; p < 0.001), reduction in left ventricular end-diastolic and end-systolic diameters, and decrease in QRS duration (167.6 ± 14.3 msec pre-implantation, 131.7 ± 11.7 msec 24 months after implantation; p < 0.001), while left atrial (LA) diameter was slightly increased (p = 0.070). The frequency of AF occurrence increased after two years of follow-up (52.4% to 56.9%, p < 0.001). Significant predictors of AF occurrence in our study population were response to CRT—AF more frequent in non-responders (B = 8.134; p < 0.001), LA diameter—AF more frequent with larger LA diameter (B = 0.813; p < 0.001), and coronary sinus (CS) lead position—AF more frequent with posterolateral in comparison with lateral CS lead position (B = 5.159; p = 0.005). Conclusions: The results of our study provide new data on AF predictors in patients with HF subjected to CRT. There remains a permanent need for new predictors, which might help in patient selection and improvement in response rate.

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Paroxysmal Atrial Fibrillation

Aboaf

Wolf²

1996

Arch Intern Med

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Paroxysmal atrial fibrillation is an extremely common form of atrial fibrillation seen by most physicians. Despite making up more than 40% of the cases of atrial fibrillation, its management continues to be neglected in the medical literature. Many of the recent large-scale prospective trials have excluded these patients. Limited data suggest that paroxysmal atrial fibrillation should be treated in a similar fashion as chronic atrial fibrillation.

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Left Atrial Size in Paroxysmal Atrial Fibrillation: Echocardiographic Evaluation and Follow-Up

Cited by 18 publications

References 15 publications

Left atrial enlargement as a predictor of recurrences in lone paroxysmal atrial fibrillation

Left atrial enlargement as a predictor of recurrences in lone paroxysmal atrial fibrillation

Predictors of Higher Frequency of Atrial Fibrillation in Patients with Cardiac Resynchronization Therapy

Paroxysmal Atrial Fibrillation

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