Left Atrial Myxoma: A Rare Nonatherosclerotic Cause of Acute Myocardial Infarction

Arcenas, Rey Francisco; Ali, Mir Ishtiaque

doi:10.1155/2013/407935

Cited by 6 publications

(6 citation statements)

References 25 publications

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“…This case features the unusual heterogeneity of atrial myxoma growth and a rare clinical presentation characterised by multiple thromboembolic events 2–7…”

Section: Discussionmentioning

confidence: 95%

An unusual presentation of atrial myxoma: thromboembolic phenomenon with a recent normal echocardiogram

et al. 2019

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“…This case features the unusual heterogeneity of atrial myxoma growth and a rare clinical presentation characterised by multiple thromboembolic events 2–7…”

Section: Discussionmentioning

confidence: 95%

An unusual presentation of atrial myxoma: thromboembolic phenomenon with a recent normal echocardiogram

et al. 2019

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“…Therefore, small animals have been extensively used in AMI-related research. The rabbit was our choice, because the rabbit heart has minimal collateral arteries; it lacks collateral blood flow after AMI; importantly, there is minimal occurrence of fatal arrhythmia and death after coronary coagulation [1, 2, 14]; both the rabbit and human have the presence of a third coronary artery in common [6]. …”

Section: Discussionmentioning

confidence: 99%

Development of a new model for acute myocardial infarction in rabbits

Tan

Xia

Xiao

et al. 2017

The Journal of Veterinary Medical Science

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The rabbit left anterior descending coronary artery is not macroscopically apparent; this often leads to failure in creation of an acute myocardial infarction (AMI) model. In order to devise a simple method with good reproducibility and high success rate for use as a rabbit AMI model, a new surgical technique was developed, in which the obtuse marginal (OM) branch of the left circumflex coronary artery was coagulated with an electric knife using a left parasternal approach. Four weeks after OM branch coagulation, an electrocardiogram (ECG), blood biochemistry analysis, echocardiographic measurements and pathologic analysis were performed. The left parasternal approach provided the surgeon clear visualization of the targeted blood vessel to accurately identify the proper site to occlude. The successful development of AMI was confirmed by ST segment elevation on the ECG, by high levels of AMI-related markers in blood samples, by cardiac functional damage reflected on echocardiographic images and by changes in pathological sections. Furthermore, an acceptable success rate and low mortality were achieved. Hence, this surgical technique was suggested to be a highly reliable and reproducible method to induce AMI in rabbits for the assessment of new therapeutic interventions or regenerative approaches.

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“…Neovascularization of the tumor mass may give a clue to its presence during cardiac catheterization. [8] A differential diagnosis has to be made with coronary artery disease associated with a cardiac myxoma. As indicated previously, cardiac myxomarelated AMI often shows a sudden onset of chest pain with elevated cardiac enzymes including cardiac troponins.…”

Section: Discussionmentioning

confidence: 99%

Cardiac myxoma: a rare cause of acute myocardial infarction

Yuan¹

2016

Turk Gogus Kalp Dama

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Bu çalışmada kardiyak miksomaya bağlı akut miyokard enfarktüsünün klinik özellikleri araştırıldı. Ça lış ma pla nı: Çalışmanın veri kaynağı 01 Ocak 1990 ve 31 Ağustos 2014 tarihleri arasındaki İngilizce literatürden kapsamlı bir veri edinimine dayandırıldı. Kardiyak miksomaya bağlı akut miyokard enfarktüsü olan toplam 48 hasta (ort. yaş 45.2±15.3 yıl; dağılım 9-70 yıl) çalışmaya dahil edildi. Bul gu lar: En yaygın başlangıç semptomu, hastaların %75.6'sında görülen göğüs ağrısı ile akut başlangıç idi. Hastaların çoğunda serum miyokard enzimlerinin düzeyi yüksekti. Anterior miyokard enfarktüsünü takiben inferior miyokard enfarktüs en yaygın olandı. Yirmi hastada (%48.8) normal bir koroner arter, 21 hastada (%51.2) koroner tıkayıcı lezyon bulunurken yedi hastada koroner koşullar belirtilmemişti. Kardiyak miksoma tanısı hastaların %83.7'sinde sadece transtorasik ekokardiyografi ile konuldu ve kardiyak miksomaların %93.3'ü sol atriyumda idi. On yedi hastada (%35.4) trombolitik veya antikoagülan tedavileri içeren konservatif tedavi tanımlandı. İki hastada cerrahi tedavi fırsatı olmaksızın ani ölüm gelişti. Kırk dört hastada (%95.7) miksoma için cerrahi rezeksiyon uygulandı. Perkütan koroner girişim iki hastada (%40) başarısız oldu. Sonuç olarak, 38 (%88.4) olaysız sağkalım, üç (%7.0) engellilikli sağkalım ve iki (%4.7) ölüm vardı. So nuç:Koroner arter hastalığın belirgin risk faktörleri olmayan genç akut miyokard enfarktüslü hastalarda miksoma ilişkili akut miyokard enfarktüsü dikkate alınmalıdır ve konvansiyonel koroner arter hastalığın ayırıcı tanısı için ekokardiyografik görüntüleme gereklidir. Koroner embolinin durumunu tanımlamak ve ileri tedaviye karar vermek için koroner anjiyogram çok önemlidir. İlişkili periferik embolik olaylar sıklıkla embolektomi gerektirir.

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Left Atrial Myxoma: A Rare Nonatherosclerotic Cause of Acute Myocardial Infarction

Cited by 6 publications

References 25 publications

An unusual presentation of atrial myxoma: thromboembolic phenomenon with a recent normal echocardiogram

An unusual presentation of atrial myxoma: thromboembolic phenomenon with a recent normal echocardiogram

Development of a new model for acute myocardial infarction in rabbits

Cardiac myxoma: a rare cause of acute myocardial infarction

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