Left atrial mechanical function and stiffness in patients with nondipper hypertension: A speckle tracking study

Demir, Mehmet; Aktaş, İbrahim; Yıldırım, Ahmet

doi:10.1080/10641963.2016.1246566

Cited by 15 publications

(17 citation statements)

References 19 publications

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“…Left atrial strain rate in uremic patients Previous studies have shown that apart from conventional Doppler echocardiography, two dimensional STI can also be used to assess LA structure and function [18,19]. The STI can track motional speckle consisting of 20-40 pixels in high frame rate two-dimensional images.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Left Atrial Function in Uremic Patients by Speckle Tracing Imaging Evaluation of LA Function in Uremic Pts by STI

Yang

Liang

et al. 2021

Preprint

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Objective: This study aimed to explore the value of speckle tracing imaging (STI) for assessment of left atrial (LA) function in uremic patients.Methods: One hundred uremic patients were divided into four groups according to the New York Heart Association (NYHA) criteria. Thirty healthy participants were enrolled as a control group. LA functional parameters were determined using conventional echocardiography. The strain rate (SR) curve of LA wall was prepared using STI, and SR in different phases of cardiac cycle were obtained.Results: The LA maximal volume (LAVmax) increased and LA passive ejection fraction (LAPEF) decreased. The LA active ejection fraction (LAAEF) showed an initial increase followed by a decrease (all p<0.05). The SR of LA lateral wall and interatrial septum (IAS) in systole (SRs-LA, SRs-IAS) and early diastole (SRe-LA, SRe-IAS) showed a steady decrease; the SR of LA lateral and IAS in late diastole (SRa-LA, SRa-IAS) showed an initial increase followed by a decrease. Compared with control group, the SRs-LA and SRs-IAS decreased in four groups with uremia (all p<0.05). A positive correlation was observed between LAPEF and the absolute value of mean peak early diastolic SR (|mSRe|) (r=0.862, p<0.05), and between LAAEF and the absolute value of mean peak late diastolic SR (|mSRa|) (r=0.756, p<0.05). LAVmax showed a negative correlation with mean peak systolic SR (mSRs) (r=-0.878, p<0.05).Conclusion: There was a significant correlation between LA function and LA strain rate in uremic patients. STI can allow for an objective and accurate evaluation of LA function in uremic patients.

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Section: Discussionmentioning

confidence: 99%

Evaluation of Left Atrial Function in Uremic Patients by Speckle Tracing Imaging Evaluation of LA Function in Uremic Pts by STI

Yang

Liang

et al. 2021

Preprint

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“…This easily obtained parameter has been postulated as an earlier marker of atrial function compromise and diastolic dysfunction, as well as being associated with follow-up events such as the appearance of atrial brillation and the occurrence of embolisms. It has been shown that the alteration of this index is even earlier than the increase in atrial volume, classically used as a prognostic variable (23)(24)(25). In a recent study by Porpáczy et al in a patient with systemic sclerosis, stiffness index is the variable that best correlates with serum levels of NT-pro-BNP, surpassing isolated LASr and LA volume (26).…”

Section: Discussionmentioning

confidence: 99%

Analysis of the left atrial function using two dimensional strain in patients with recent diagnosis of hereditary hemochromatosis

Saad

Aladio

Yamasato

et al. 2021

European Heart Journal - Cardiovascular Imaging

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Funding Acknowledgements Type of funding sources: None. Background. Hereditary hemochromatosis (HH) is a genetic condition associated with a systemic iron overload caused by a reduction in the concentration of the iron regulatory hormone hepcidin or the hepcidin-ferroportin complex activity. Heart failure is the leading cause of death. It has been demonstrated early stages of systolic and diastolic left ventricular dysfunction in previous studies. The main function of the left atrium (LA) is to modulate the left ventricular filling through the reservoir, conduct and bump phases. Purpose. To compare the LA function between asymptomatic and recently diagnosed HH patients and a control group using two-dimensional speckle tracking. Methods. In this prospective study, 30 patients with HH (90% males, 47 ± 18 years old) and 30 healthy controls with a normal echo stress test (85% males, 45 ± 13 years old) were included. A conventional echocardiogram was performed. LA strain, LA strain rate and LA volumetric parameters during the reservoir, conduit and bump phases were studied according to the current recommendations. The LA stiffness index was calculated by using the ratio between E/e´ ratio and LA strain during the reservoir phase. Results. LA volume was similar in both groups (36,5 ± 10 ml vs 32,3 ± 6,5 ml; p = 0.09). No differences were observed in LA ejection fraction (EF) (57.5 ± 10% vs 60 ± 5%; p = 0.32), LA passive EF (35 ± 12% vs 36 ± 9%; p = 0.82) or LA bump function (34 ± 11% vs 36 ± 9.9%; p = 0.41) between both groups. On the contrary, the HH group had lower LA reservoir strain (31.5 ± 6.5% vs 38.3 ± 7.9%; p = 0.002) and during the conduct phase (18 ± 7% vs 23.3 ± 6.4%; p = 0.01) than the control group. The LA stiffness index was significantly higher in the HH group (25.5 ± 9.1 vs 19.5 ± 6.4; p = 0.01). Conclusion. Early abnormalities in the LA function could be detected by using two-dimensional speckle tracking study despite no evidence of changes in atrial size or volumetric parameters. Abstract Figure.

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“…Measurement of left atrial stiffness (LASI) [11] The two-chamber and four-chamber dynamic two-dimensional cardiac cycle data were collected and analyzed by Qlab10.5 workstation software,and PALS was measured by2D-STI,E/e' ratio to PALS was obtained to calculate LASI.…”

Section: Echocardiographic Measurementsmentioning

confidence: 99%

A Preliminary Study of Left Atrial Function and Left Atrial Stiffness in Type 2 Diabetic Patients with Normotensive Patients Without Symptomatic Cardiovascular Disease

Huang

Zhu

et al. 2021

Preprint

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Background: The purpose of this study was to investigate the relationship between left atrial function and left atrial stiffness in type 2 diabetic patients.Methods: A total of 41 healthy subjects (controls) and 39 patients with type 2 diabetes mellitus (DM2 patients) were enrolled in this study. The left atrial volume index was measured by biplanar Simpson method. The early and late diastolic velocities (e'and a') were measured by tissue Doppler in lateral and septal boeder of the mitral annulus. Lateral and septal myocardial velocities were averaged. E/eʹ ratio was computed.The peak atrial longitudinal strain (PALS) was analyzed by tow-dimensional speckle tracking imaging (2D-STI) technique.The ratio of E/e ' to PALS was used as an indicator of LASI.Results:The maximum volume (LAVImax), minimum volume (LAVImin) and pre-contraction volume (LAVIpre) of the left atrium in DM2 patients were significantly higher than those in the control groups, and the differences were statistically significant (P<0.05). The difference between PALS decrease and LASI increase was statistically significant (P<0.05).PALS and LASI were statistically correlated with three phase volume index of left atrial and E/e'ratio. LASI was superior to PALS and left atrial volume index in diagnosing diabetic normotensive patients without symptomatic cardiovascular disease.Conclusion: Compared with the controls, PALS decreased and LASI increased in DM2. PALS and LASI were significantly correlated with left atrial volume and E/e’. LASI showed the highest diagnostic efficacy in the diagnosis of diabetes. PALS and LASI can be used as indicators for early evaluation of left atrial function in patients with DM2.Trial registration number:+86-17856931224;date of registration:May 3,2021

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Left atrial mechanical function and stiffness in patients with nondipper hypertension: A speckle tracking study

Cited by 15 publications

References 19 publications

Evaluation of Left Atrial Function in Uremic Patients by Speckle Tracing Imaging Evaluation of LA Function in Uremic Pts by STI

Evaluation of Left Atrial Function in Uremic Patients by Speckle Tracing Imaging Evaluation of LA Function in Uremic Pts by STI

Analysis of the left atrial function using two dimensional strain in patients with recent diagnosis of hereditary hemochromatosis

A Preliminary Study of Left Atrial Function and Left Atrial Stiffness in Type 2 Diabetic Patients with Normotensive Patients Without Symptomatic Cardiovascular Disease

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