Left atrial functional changes as emerging diagnostic and prognostic marker

Floria, Mariana; Burlacu, Alexandru

doi:10.1002/jcu.23168

Cited by 1 publication

(1 citation statement)

References 15 publications

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“…Therefore, no information about right atrial fibrosis could be obtained. Fourth, left atrial function assessment by speckled tracking echocardiography may predict recurrence of atrial tachyarrhythmia including AT 27 ; however, we did not analyze in this study. Further studies will be needed to predict AT recurrence with a noninvasive method even before initial procedure.…”

Section: Discussionmentioning

confidence: 88%

Reverse structural left atrial remodeling and atrial tachycardia in patients with repeat ablation for atrial fibrillation

Hashiguchi

Chiang

Rottner

et al. 2022

Pacing Clinical Electrophis

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Background Catheter ablation has been evolved to a cornerstone in the therapy of atrial fibrillation (AF); however, atrial tachycardias (AT) after AF ablation are still an important issue. Besides the electrical recurrence of atrial tachyarrhythmia after ablation, left atrial (LA) remodeling has received attention as a consequence of AF. Objective The aim of this study is to evaluate predictors for AT recurrence and LA remodeling in patients with repeat AF ablation procedures. Methods and Results One hundred thirteen patients who underwent repeat AF ablation with 3D electro‐anatomical mapping system were evaluated. Mean age was 63.1 ± 9.3 years, and 2.3 ± 0.5 ablation procedures were performed during a time period of 22 [IQR 7;48] months. Reverse structural LA remodeling (LA volume decreased more than 15%) was observed in 25 (22.1%) patients. LA volume index (LAVI) during first procedure was the only predictor for positive reverse structural LA remodeling (hazard ratio (HR): 1.03, 95% CI: 1.00–1.07, p = .036) in multivariate analysis. Fifty‐nine (52.2%) patients experienced only AF and 54 (47.8%) patients AT after first procedure. Female gender (HR: 5.21, 95% CI: 1.66–18.08, p = .006), LAVI (HR: 1.06, 95% CI: 1.02–1.11, p = .008) and LA scar percentage (HR: 1.08, 95% CI: 1.02–1.17, p = .019) were independent significant predictors for AT recurrence in multivariate analysis. Conclusions Reverse structural LA remodeling occurred in a quarter of patients with repeat ablation procedures for AF. Only larger LAVI during first procedure predicted reverse structural LA remodeling. Half of the patients experienced AT between first and last ablation procedure. Female gender, larger LAVI and larger scar area were significant predictors for AT after catheter ablation for AF.

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Section: Discussionmentioning

confidence: 88%