Lectin-like and bacterial-agglutinating activities of heat shock proteins Hsp5 and Hsp90α from amphioxus Branchiostoma japonicum

Yao, Lan; Qu, Baozhen; Ma, Zhiyu; Chen, Ying; Tan, Yibo; Gao, Zhan; Zhang, Shicui

doi:10.1016/j.fsi.2019.10.074

Cited by 10 publications

(3 citation statements)

References 45 publications

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“…Previous studies have conjected that HSPs might be able to form complexes with microbial products and ,consequently, activates the innate immune system (Wallin et al, 2002). HSP5 and HSP90α that identified in Branchiostoma japonicum displayed bacterial‐agglutinating to both the Gram‐negative and Gram‐positive bacteria (Yao et al, 2019), and HSP70 from L. vannamei showed antiviral activity (Janewanthanakul et al, 2019). In this study, bacterial binding and antibacterial assay showed that the three sHSPs displayed distinct binding and antibacterial activities towards bacteria.…”

Section: Discussionmentioning

confidence: 99%

“…Similar to other types of HSPs, sHSPs are involved in dealing with a wide variety of abiotic stress, such as heat/cold stress, osmotic stress, hypoxia, heavy metals and organic pollutants exposure (Mohindra et al, 2015;Music et al, 2014;Shi et al, 2016;Yuan et al, 2019). Furthermore, previous studies have shown that sHSPs also participated in immune responses (Bakthisaran et al, 2015;Janewanthanakul et al, 2019;Kargul & Laurent, 2012;Yao et al, 2019). However, the manner by which sHSPs exert their immune function remains largely unknown.…”

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confidence: 99%

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Bacteria binding and antibacterial activities of three small heat shock protein from the swimming crab, Portunus trituberculatus

Zhang

Zheng

et al. 2022

Aquaculture Research

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The swimming crab, Portunus trituberculatus, is one of the most important commercial crabs cultured in China, with a total yield of approximately 100,000 tons (Fisheries Bureau of Agriculture Ministry of China, 2019). In recent decade, despite the increasing development of the P. trituberculatus farming industry, diseases caused by bacterial infection have caused tremendous economic losses and posed serious threats to the sustainable and healthy development of P. trituberculatus aquaculture industry. Excavating immune-related molecules from host, especially antibacterial molecules, will provide theoretical guidance and candidate therapeutic agents to address the disease problem.Heat shock proteins (HSPs), which widely exist in prokaryotes and eukaryotes, are molecular chaperones that play critical roles in maintaining cellular homeostasis (Schlesinger, 1990;Sikora & Grzesiuk, 2007). According to their homology and molecular mass, HSPs can be grouped into several families, including HSP110, HSP100, HSP90, HSP70, HSP60 and small molecular mass HSPs (sHSPs) (Craig et al., 1994;Tang et al., 2011). HSPs play a primary role

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Bacteria binding and antibacterial activities of three small heat shock protein from the swimming crab, Portunus trituberculatus

Zhang

Zheng

et al. 2022

Aquaculture Research

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“…Besides the antibacterial molecules listed above, there are several other molecules, such as fibrinogen-related protein (Fan et al 2008), transferrin ), Gram-negative bacteria-binding proteins (Jin et al 2012), alpha-2 macroglobulin (Pathirana et al 2016), avidin (Guo et al 2017, Miple (Gao et al 2018), HSP5 and HSP90α (Yao et al 2019), that play roles in the defense system of amphioxus. These molecules are primarily produced in the hepatic cecum.…”

Section: Other Immune-relevant Effectorsmentioning

confidence: 99%

Hepatic cecum: a key integrator of immunity in amphioxus

Zhang

et al. 2021

Mar Life Sci Technol

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The vertebrate liver is regarded as an organ essential to the regulation of immunity and inflammation as well as being central to the metabolism of nutrients. Here, we discuss the functions that the hepatic cecum of amphioxus plays in the regulation of immunity and inflammation, and the molecular basis of this. It is apparent that the hepatic cecum performs important roles in the immunity of amphioxus including immune surveillance, clearance of pathogens and acute phase response. Therefore, the hepatic cecum, like the vertebrate liver, is an organ functioning as a key integrator of immunity in amphioxus.

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Multiple isoforms of HSP70 and HSP90 required for betanodavirus multiplication in medaka cells

Zenke

Okinaka

2022

Arch Virol

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Lectin-like and bacterial-agglutinating activities of heat shock proteins Hsp5 and Hsp90α from amphioxus Branchiostoma japonicum

Cited by 10 publications

References 45 publications

Bacteria binding and antibacterial activities of three small heat shock protein from the swimming crab, Portunus trituberculatus

Bacteria binding and antibacterial activities of three small heat shock protein from the swimming crab, Portunus trituberculatus

Hepatic cecum: a key integrator of immunity in amphioxus

Multiple isoforms of HSP70 and HSP90 required for betanodavirus multiplication in medaka cells

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