Lecithin Decreases Human Milk Fat Loss During Enteral Pumping

Chan, Michelle Mei Fung; Nohara, Masaru; Chan, Benjamin R.; Curtis, Julie; Chan, Gary M.

doi:10.1097/00005176-200305000-00004

Cited by 16 publications

(15 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…If we also consider the negative effect of freezing at À208C before pasteurization (14) and the process of thawing and subsequent administration (33,34,(37)(38)(39), the magnitude of the effect could be much more clinically relevant.…”

Section: Discussionmentioning

confidence: 99%

Effect of Holder Pasteurization and Frozen Storage on Macronutrients and Energy Content of Breast Milk

García-Lara¹,

Vieco²,

Cruz-Bértolo

et al. 2013

J. pediatr. gastroenterol. nutr.

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Effect of Holder Pasteurization and Frozen Storage on Macronutrients and Energy Content of Breast Milk

García-Lara¹,

Vieco²,

Cruz-Bértolo

et al. 2013

J. pediatr. gastroenterol. nutr.

View full text Add to dashboard Cite

show abstract

“…The dams were killed after milk collection. Caloric, fat, and protein content were determined as previously described (10,64,92). Mineral analysis was performed by atomic absorption spectrometry as described above.…”

Section: Methodsmentioning

confidence: 99%

Uteroplacental insufficiency affects epigenetic determinants of chromatin structure in brains of neonatal and juvenile IUGR rats

Lei

James³

et al. 2006

Physiological Genomics

128

102

View full text Add to dashboard Cite

Intrauterine growth retardation (IUGR) increases the risk of neuroendocrine reprogramming. In the rat, IUGR leads to persistent changes in cerebral mRNA levels. This suggests lasting alterations in IUGR cerebral transcriptional regulation, which may result from changes in chromatin structure. Candidate nutritional triggers for these changes include altered cerebral zinc and one-carbon metabolite levels. We hypothesized that IUGR affects cerebral chromatin structure in neonatal and postnatal rat brains. Rats were rendered IUGR by bilateral uterine artery ligation; controls (Con) underwent sham surgery. At day of life 0 (d0), we measured cerebral DNA methylation, histone acetylation, expression of chromatin-affecting enzymes, and cerebral levels of one-carbon metabolites and zinc. At day of life 21 (d21), we measured cerebral DNA methylation and histone acetylation, as well as the caloric content of Con and IUGR rat breast milk. At d0, IUGR significantly decreased genome-wide and CpG island methylation, as well as increased histone 3 lysine 9 (H3/K9) and histone 3 lysine 14 (H3/K14) acetylation in the hippocampus and periventricular white matter, respectively. IUGR also decreased expression of the chromatin-affecting enzymes DNA methyltransferase 1 (DNMT1), methyl-CpG binding protein 2 (MeCP2), and histone deacetylase (HDAC)1 in association with increased cerebral levels of zinc. In d21 female IUGR rats, cerebral CpG DNA methylation remained lower, whereas H3/K9 and H3/K14 hyperacetylation persisted in hippocampus and white matter, respectively. In d21 male rats, IUGR decreased acetylation of H3/K9 and H3/K14 in these respective regions compared with controls. Despite these differences, caloric, fat, and protein content were similar in breast milk from Con and IUGR dams. We conclude that IUGR results in postnatal changes in cerebral chromatin structure and that these changes are sex specific.

show abstract

“…2,[6][7][8] Until the last several years, the creamatocrit was used almost exclusively in the research setting, either in field studies in which more complicated human milk analyses were not feasible, [9][10][11][12][13][14][15] or clinical investigations that sought to measure milk lipid changes in response to an independent variable. [16][17][18][19][20][21][22] For example, Mitoulas et al 19 used the creamatocrit to compare the completeness of breast emptying for different milk expression patterns with an electric pump, Brennan-Behm et al 21 used the creamatocrit to determine which type of infusion tubing resulted in the least lipid loss during continuous gavage infusion of mothers' milk for premature infants, and Askit et al 20 used it to measure the association between the lipid in mothers' milk and infant sucking characteristics.…”

Section: Introductionmentioning

confidence: 99%

Accuracy of a User-Friendly Centrifuge for Measuring Creamatocrits on Mothers' Milk in the Clinical Setting

Meier

Engstrom

Zuleger

et al. 2006

Breastfeeding Medicine

View full text Add to dashboard Cite

The creamatocrit (CRCT), a simple, accurate, and inexpensive technique for the estimation of lipid and caloric content in mothers' milk, has been used extensively in lactation research, but has not been integrated into the routine management of clinical lactation problems such as slow weight gain in mothers' milk-fed preterm and term infants. The Creamatocrit Plus is a lightweight, noiseless centrifuge with an embedded reader that automatically calculates lipid and calories from the CRCT value, making it ideal for use in the clinical setting. This study compared intra-user and inter-user reliability, the equivalence of the CRCT values obtained with the Creamatocrit Plus to the two standard techniques for performing CRCTs: the standard laboratory centrifuge with a hematocrit reader and the standard laboratory centrifuge with digital calipers, and the predictive accuracy of the Creamatocrit Plus for estimating the lipid and caloric content in mothers' milk. CRCTs were performed using the three techniques on 36 milk specimens from 12 women. Laboratory analyses of lipid and calories were performed by investigators blinded to CRCT values. The mean absolute intra-user and inter-user differences were all <1% CRCT, and the mean CRCT measures were nearly identical for the three measurement techniques. Linear correlations between CRCT and laboratory measures for lipid (r = 0.95) and calories (r = 0.94) were very high. The authors conclude that the Creamatocrit Plus can replace cumbersome laboratory equipment for measuring CRCTs in the clinical setting.

show abstract

Lecithin Decreases Human Milk Fat Loss During Enteral Pumping

Abstract: The addition of 1 g soy lecithin per 50 mL milk decreased the human milk fat loss during intermittent pumping and may help infants receive more calories from human milk administered by pump.

Cited by 16 publications

References 11 publications

Effect of Holder Pasteurization and Frozen Storage on Macronutrients and Energy Content of Breast Milk

Effect of Holder Pasteurization and Frozen Storage on Macronutrients and Energy Content of Breast Milk

Uteroplacental insufficiency affects epigenetic determinants of chromatin structure in brains of neonatal and juvenile IUGR rats

Accuracy of a User-Friendly Centrifuge for Measuring Creamatocrits on Mothers' Milk in the Clinical Setting

Contact Info

Product

Resources

About