Lead poisoning in Indian silver refiners

Tandon, S. K.; Chatterjee, Mainak; Bhargava, Aditi; Shukla, Vinay J; Bihari, Vipin

doi:10.1016/s0048-9697(01)00845-2

Cited by 59 publications

(32 citation statements)

References 16 publications

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“…In a study of silver refining (involving lead smelting) workers with mean blood lead levels of 32.84 μg/dL and symptoms of lead toxicity (anemia, muscle wasting, abdominal colic) were given vitamin C to evaluate the ability of this supplements to affect lead exposure. With continuous lead exposure and 250 mg vitamin C twice daily for 30 days, significantly lowered blood lead levels [47]. Lead-induced ROS production as examined by rat sperm chemiluminescence generation reduced by 40% with supplementation of 500 mg vitamin C/l drinking water [48].…”

Section: Resultsmentioning

confidence: 99%

Lead acetate induced oxidative stress and its possible reversal by Tribulus terrestris root extract in testes of Swiss albino mice

Khairwal¹

2013

IOSR-JESTFT

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Section: Resultsmentioning

confidence: 99%

Lead acetate induced oxidative stress and its possible reversal by Tribulus terrestris root extract in testes of Swiss albino mice

Khairwal¹

2013

IOSR-JESTFT

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“…Tandon et al (2001) had been reported that effects of Pb on humans include anemia, abdominal colic, and gum wastage, while Cd alters calcium and phosphorus metabolism, thus contributing to arthritis, osteoporosis, and neuromuscular diseases. These effects may have been common in ancient times in such a severely polluted landscape.…”

Section: Discussionmentioning

confidence: 99%

Estimation of toxic elements in the samples of different cigarettes and their effect on the essential elemental status in the biological samples of Irish smoker rheumatoid arthritis consumers

Afridi

Talpur

Kazi

et al. 2015

Environ Monit Assess

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Cigarette smoking interferes with the metal homeostasis of the human body, which plays a crucial role for maintaining the health. A significant flux of heavy metals, among other toxins, reaches the lungs through smoking. In the present study, the relationship between toxic element (TE) exposure via cigarette smoking and rheumatoid arthritis incidence in population living in Dublin, Ireland, is investigated. The trace {zinc (Zn), copper (Cu), manganese (Mn), and selenium (Se)} and toxic elements arsenic (As), cadmium (Cd), mercury (Hg), and lead (Pb) were determined in biological (scalp hair and blood) samples of patients diagnosed with rheumatoid arthritis, who are smokers living in Dublin, Ireland. These results were compared with age and sex-matched healthy, nonsmoker controls. The different brands of cigarette (filler tobacco, filter, and ash) consumed by the studied population were also analyzed for As, Cd, Hg, and Pb. The concentrations of trace and TEs in biological samples and different components of cigarette were measured by inductively coupled plasma mass spectrophotometer after microwave-assisted acid digestion. The validity and accuracy of the methodology were checked using certified reference materials. The recovery of all the studied elements was found to be in the range of 96.4-99.8 % in certified reference materials. The filler tobacco of different branded cigarettes contains Hg, As, Cd, and Pb concentrations in the ranges of 9.55-12.4 ng, 0.432-0.727 μg, 1.70-2.12 μg, and 0.378-1.16 μg/cigarette, respectively. The results of this study showed that the mean values of As, Cd, Hg, and Pb were significantly higher in scalp hair and blood samples of rheumatoid arthritis patients as compare to healthy controls, while Zn, Cu, Mn, and Se concentrations were found to be lower in rheumatoid arthritis patients, the difference was significant in the case of smoker patients (p<0.001). The levels of four toxic elements were 2-3-folds higher in scalp hair and blood samples of nonrheumatoid arthritis smoker subjects as compared to nonsmoker controls. The high exposure of toxic metals as a result of cigarette smoking may be synergistic with risk factors associated with rheumatoid arthritis.

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“…Tandon et al [4] in his study noted that the effects of Pb on humans include anemia, abdominal colic, and gum wastage, while Cd alters calcium (Ca) and phosphorus metabolism, thus contributing to arthritis, osteoporosis, and neuromuscular diseases. Toxic elements (Cd, Pb, and Ni) may deplete glutathione and protein-bound sulfhydryl groups, resulting in the production of reactive oxygen species, such as superoxide anion, hydrogen peroxide, and hydroxyl radical [29].…”

Section: Discussionmentioning

confidence: 99%

“…The role of Zn in healthy aging is particularly important as it prevents neoplastic cell growth and is involved in mitotic cell division, and DNA and RNA repair. Chronic diseases associated with alterations in Zn status are bronchial asthma and rheumatoid arthritis [4]. Zinc plays an important role in nucleic acid synthesis, transcription, and translation as a cofactor for some of the enzymes involved and may therefore participate in a broad range of metabolic activities in bone.…”

Section: Introductionmentioning

confidence: 99%

Interaction Between Zinc, Cadmium, and Lead in Scalp Hair Samples of Pakistani and Irish Smokers Rheumatoid Arthritis Subjects in Relation to Controls

Afridi

Kazi

Brabazon

et al. 2012

Biol Trace Elem Res

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The incidence of rheumatoid arthritis (RA) has been associated with cigarette smoking. The aim of our study was to assess the trace essential and toxic metals, cadmium (Cd), lead (Pb), and zinc (Zn), in scalp hair samples of 32 Irish and 46 Pakistani smokers and non-smokers RA male patients with age range 42-56 years. For comparison purpose, the scalp hair samples of 27 Irish and 55 Pakistani non-RA male subjects of the same age group were collected. The concentrations of trace and toxic elements were measured by inductive coupled plasma atomic emission spectrophotometer and atomic absorption spectrophotometer prior to microwave-assisted acid digestion. The validity and accuracy of the methodology was checked using certified reference materials and using conventional wet acid digestion method on the same certified reference materials (CRMs). The recovery of all studied elements was found to be in the range of 97.5-99.7% of certified reference values of CRMs. The results of this study showed that the mean values of Cd and Pb were significantly higher in scalp hair samples of both smoker and non-smoker RA patients than in referents (P<0.001), whereas the concentration of Zn was lower in the scalp hair samples of smokers and non-smokers rheumatoid arthritis patients. The deficiency of Zn and the high exposure of Cd and Pb as a result of cigarette smoking may be synergistic risk factors associated with rheumatoid arthritis.

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Lead poisoning in Indian silver refiners

Cited by 59 publications

References 16 publications

Lead acetate induced oxidative stress and its possible reversal by Tribulus terrestris root extract in testes of Swiss albino mice

Lead acetate induced oxidative stress and its possible reversal by Tribulus terrestris root extract in testes of Swiss albino mice

Estimation of toxic elements in the samples of different cigarettes and their effect on the essential elemental status in the biological samples of Irish smoker rheumatoid arthritis consumers

Interaction Between Zinc, Cadmium, and Lead in Scalp Hair Samples of Pakistani and Irish Smokers Rheumatoid Arthritis Subjects in Relation to Controls

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