Lead effect on blood pressure in moderately lead‐exposed male workers

Abstract

Long-term cumulative Pb exposure, which is better reflected by EP than by ALAD or current BPb level, can significantly increase blood pressure in moderately Pb-exposed male workers (long-term average BPb <400 microg/l; exposure duration 2-21 years).

Age- and Gender-Based Studies of Trace Metal Levels and Various Enzymes Associated with Myocardial Infarction

“…This is in agreement with the previous studies where MI patients are reported to have enhanced levels of lead in blood than in normal ones [28]. In serum, lead mainly occurs as the cellular constituent of erythrocytes [29,30], and its high levels have been found to be associated with various unwanted affects, the most important of which is the rise in blood pressure, which may lead to various cardiovascular disorders [31,32]. With the mean age of 46.1 years, the first group represented the order of the metals as Mg > Fe > Cu > Pb > Cr > Co. A similar order of mean metal levels persisted for second age group.…”

Occupational Lead Exposure: Blood Lead Levels of Apprentices in Bursa, Turkey

“…Human studies have generally provided less conclusive evidence for the role of lead and/or cadmium in hypertension 24) . It has been reported that long-term occupational exposure is related to a slight increase in both systolic and diastolic blood pressure 25) .…”

Xenobiotic action on steroid hormone synthesis and sulfonation the example of lead and polychlorinated biphenyls

“…Corticosterone may be converted to aldosterone, a mineral corticoid whose production is controlled by a multifactorial system, as a consequence of acute and chronic changes in body sodium and potassium contents. The eVect may also be relevant in hormonal and renal leadinduced mechanisms of arterial hypertension (Apostoli et al 2005b;Telisman et al 2004). …”