Lead concentrations in whole blood, serum, saliva and house dust in samples collected at two time points (12 months apart) in Santo Amaro, BA, Brazil

Guerra, Carolina de Souza; Magna, Gustavo Alonso Muñoz; Machado, Sandro Lemos; Capitani, Eduardo Mello De; Ramos, J. Galvão; Peixoto, Iza Teixeira Alves; Peixoto, Aníbal Araujo Alves; Moreno, Maria Lucia Vieira; Alva, Juan Carlos Rossi; Nakadi, Flávio V.; Veiga, Márcia Andréia Mesquita Silva da; Barbosa, Fernando; Gerlach, Raquel Fernanda; Carvalho, Míriam de Fátima

doi:10.1016/j.envres.2015.05.023

Cited by 12 publications

(1 citation statement)

References 24 publications

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“…The levels of exposure in this study were similar to what have been shown in studies conducted in Santo Amaro Ba, Brazil, where two samples were collected over 12 months. At the first time point the level of Pb in serum was 0.01-1.82 µg/L while one year later there was a reduction in levels of Pb in serum to 0.04-0.66, consistent with reduction of Pb in the environment in this city (de Souza Guerra et al, 2015). Serum is considered to be a good biomarker for Pb exposure and some studies report a high degree of correlation between serum and whole blood levels (Hernández-Avila et al, 1998;Rezende et al, 2010).…”

Section: Discussionmentioning

confidence: 65%

Evaluation of alterations in dopamine and neuro-toxicity caused by co-exposure to lead (Pb) and polychlorinated biphenyls (PCBs)

Enayah¹

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for their valuable advice and guidance with my project throughout the years. I would like to specially thank Dr. Jonathan Doorn for his rational and logical suggestions and for training me to do assays needed in the project. I am deeply grateful for the help of Susanne Flor, our lab manager. She rendered lots of help in project assistance, ordering experiment reagents and keeping the lab organized. I would also like to thank the following lab mates and colleagues for their suggestions, support and project assistance, Dr. William D Klaren, Gopi S. Gadupudi, Miao Li. I am grateful for your companionship, help and encouragement during the years I live in Iowa City. Finally, I would like to thank my husband Dr. Abdul Aladheem and my kids Moheamn, Moeimeal and Elaf for their unconditional love, support, and confidence in me. I would not be where I am today without their trust, encouragement and love. Thank you all.

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Section: Discussionmentioning

confidence: 65%

Evaluation of alterations in dopamine and neuro-toxicity caused by co-exposure to lead (Pb) and polychlorinated biphenyls (PCBs)

Enayah¹

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Biological Monitoring of Exposure to Industrial Chemicals

Hopf

Fustinoni

2021

Patty's Industrial Hygiene

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Human biological monitoring is a powerful tool for scientists, policy makers, and occupational health‐care professionals, such as physicians and occupational hygienists, to assess and manage health risks associated with chemical exposures among the general population as well as at the workplace. This chapter will focus on using biological monitoring in occupational exposure assessments. It includes biological monitoring sampling strategies and practical approaches. Relevant biomarkers used in biomonitoring are derived based on fundamental understanding of absorption, distribution, metabolism, and excretion (ADME) of chemicals. Therefore, ADME will be discussed along with toxicokinetics and toxicodynamics. Individual susceptibility is a topic associated with biological monitoring as opposed to air monitoring. Monitoring variability associated with air and biological monitoring is compared. The biomonitoring strategy choice is dependent on the purpose, selected biomarker, matrix (urine, blood, saliva, hair, exhaled breath, exhaled breath condensate), sampling time, which is determined based on the selected biomarkers apparent elimination half‐life, and variability but also on the purpose of the biomonitoring program. Biological limit values are established on available scientific data. Their historic development and concepts are country specific. Biomonitoring of metals and inorganic compounds as well as organic compounds are extensively covered. Emerging biomarker fields as well as new chemical analytical methods are briefly discussed. Future trends in human biological monitoring are discussed as it is a current topic in public health policies, in occupational and environmental health and in science in general.

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Salivary Bioscience and Environmental Exposure Assessment

Panuwet

DʼSouza

Phillips

et al. 2020

Salivary Bioscience

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Lead concentrations in whole blood, serum, saliva and house dust in samples collected at two time points (12 months apart) in Santo Amaro, BA, Brazil

Abstract: Results support the validity of lead determination in blood and in house dust to assess lead exposure over time. However, lead in blood and lead in dust did not correlate with lead in serum or lead in saliva.

Cited by 12 publications

References 24 publications

Evaluation of alterations in dopamine and neuro-toxicity caused by co-exposure to lead (Pb) and polychlorinated biphenyls (PCBs)

Evaluation of alterations in dopamine and neuro-toxicity caused by co-exposure to lead (Pb) and polychlorinated biphenyls (PCBs)

Biological Monitoring of Exposure to Industrial Chemicals

Salivary Bioscience and Environmental Exposure Assessment

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