The last decade witnessed the emergence of green information technology(GIT) which includes organizational initiatives to reduce the negative impact of information technology (IT) on the environment. GIT has gained considerable interest among researchers because of a huge negative impact on the environment and an extensive use of information technology. A research instrument has been developed to link three components: coercive pressure, normative influence, and mimicry and stdy their effect on GIT adopt and continuance intentions. The model is validated using data collected from a field survey of 99 managers of small enterprises (SEs) in Thi-Qar province. The analysis that normative pressures are the most influential in the adoption of green IT. The coercive pressures have the most significant effect on the continuance usage of GIT practices. The current study would contribute to illustrate knowledge in the field of IT, regarding the decision maker's intention for the adoption and continue using GIT through the development of a theoretical framework that identified the key factors of GIT adoption and intention continuance.
Although its mechanism of action on cancer cells not well understood, Metformin (Met) is widely used nowadays to improve the anticancer activity of some drugs. Metformin has also been shown to decrease the growth of breast cancer cells and pancreatic cancer in hamsters and delays other types of tumors. The aim of this study was to compare the effects of Cisplatin (Cis) alone and Metformin alone on colon cancer cell line SW480. The results showed that the effect of Metformin on cell proliferation is concentration-dependent. Metformin enhances the proliferation and attachment of colon cancer at lower concentrations. Results showed a significant decrease in cell proliferation and attachment of colon cancer cells after Cisplatin treatment.Results of this study revealed that Cisplatin treatment decreased both proliferation and cell adhesion to the matrix. Combination therapy (Met+Cis) showed promising synergism and enhancement of anticancer activity of Cisplatin on colon cancer cells. We are strongly recommended more investigations to be more specific for using Metformin as general anticancer.
for their valuable advice and guidance with my project throughout the years. I would like to specially thank Dr. Jonathan Doorn for his rational and logical suggestions and for training me to do assays needed in the project. I am deeply grateful for the help of Susanne Flor, our lab manager. She rendered lots of help in project assistance, ordering experiment reagents and keeping the lab organized. I would also like to thank the following lab mates and colleagues for their suggestions, support and project assistance, Dr. William D Klaren, Gopi S. Gadupudi, Miao Li. I am grateful for your companionship, help and encouragement during the years I live in Iowa City. Finally, I would like to thank my husband Dr. Abdul Aladheem and my kids Moheamn, Moeimeal and Elaf for their unconditional love, support, and confidence in me. I would not be where I am today without their trust, encouragement and love. Thank you all.
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