Lead aVR is a predictor for mortality in heart failure with preserved ejection fraction

İçen, Yahya Kemal; Urgun, Örsan Deniz; Dönmez, Yurdaer; Demirtaş, Abdullah; Koç, Mevlüt

doi:10.1016/j.ihj.2018.07.001

Cited by 6 publications

(6 citation statements)

References 24 publications

(32 reference statements)

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“…In another study, in patients with anterior myocardial infarction, positive T wave in lead aVR showed global left ventricular ischemia. Recent studies have shown that the T-wave positivity in the lead aVR is a marker of ventricular repolarization abnormality and provides information on short- and long-term cardiovascular mortality in patients with heart failure, patients with anterior myocardial infarction, and those who receive hemodialysis for various reasons 15 – 17 . In their long-term follow-up study of male individuals, Tan et al showed that the T-wave positivity is an independent risk factor for cardiovascular events 20 .…”

Section: Discussionmentioning

confidence: 99%

“…However, it provides prognostic information on many cardiovascular diseases. A positive T-wave amplitude in the lead aVR gives prognostic information on repolarization abnormality and provides diagnostic and prognostic information on many cardiovascular diseases such as in heart failure 15 – 17 . However, there is no information regarding its relationship with COVID-19 pneumonia.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Prognostic Value of T-wave Positivity in Lead aVR in COVID-19 Pneumonia

Sivri¹,

Özdemir

Çelik³

et al. 2022

Rev. Assoc. Med. Bras.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Prognostic Value of T-wave Positivity in Lead aVR in COVID-19 Pneumonia

Sivri¹,

Özdemir

Çelik³

et al. 2022

Rev. Assoc. Med. Bras.

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“…In addition, lead aVR ST elevation could represent a "mirror image" of ST depression in the lateral leads, which reflects diffuse LV subendocardial ischemia (19,20). aVRT+ has been associated with unfavorable outcome in patients with an implantable cardioverterdefibrillator, heart failure with preserved LV ejection fraction, transcatheter aortic valve implantation, ischemic cardiomyopathy, and hemodialysis therapy (6,7,21,22,23).…”

Section: Discussionmentioning

confidence: 99%

“…The T wave in lead aVR is normally negative due to the unique location of this augmented extremity lead. However, previous studies have shown that a positive or isoelectric T wave (aVRT+) in a routine 12-lead ECG is an independent prognostic predictor of cardiovascular mortality in the general population as well as in cardiovascular disease (1)(2)(3)(4)(5)(6)(7)(8). Changes in lead aVR are also important in the differential diagnosis of tachyarrhythmias (9).…”

Section: Introductionmentioning

confidence: 99%

The prognostic significance of a positive or isoelectric T wave in lead aVR in patients with acute coronary syndrome and ischemic ECG changes in the presenting ECG - Long-term follow-up data of the TACOS study

Siren

Koivula

Eskola

et al. 2020

Journal of Electrocardiology

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Background. A positive T wave in lead aVR (aVRT+) is an independent prognostic predictor of cardiovascular mortality in the general population as well as in cardiovascular disease.Subjects and Methods. We evaluated the prognostic impact of aVRT+ in an ECG recorded as close to hospital discharge as possible in acute coronary syndrome patients (n=527). We divided the patients into three categories based on the findings in the admission ECG: ST elevation, global ischemia and other ST/T changes.Results. In the whole study population, and in all the three ECG subgroups, the 10-year all-cause mortality rate was higher in the aVRT+ group than in the aVRT-group. In Cox regression analysis, the age and gender adjusted hazard ratio (HR) for aVRT+ to predict all-cause mortality in the whole study population was 1.43 (95% confidence interval [CI] 1.12-1.83; p=0.004). To predict cardiovascular mortality, the age and gender adjusted HR for aVRT+ was 1.54 (95% CI 1.14-2.07; p=0.005) in the whole study population and 2.07 (95% CI 1.07-4.03; p=0.032) in the category with other ST/T changes. Conclusion.In ACS patients with or without ST elevation, but with ischemic ST/T changes in their presenting ECG, a positive or isoelectric T wave in lead aVR in an ECG recorded in the subacute in-hospital stage is associated with all-cause and cardiovascular mortality during long-term follow-up. Clinicians should pay attention to this simple ECG finding at hospital discharge.

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“…However, it provides prognostic information on many cardiovascular diseases. A positive T-wave amplitude in the lead aVR gives prognostic information on repolarization abnormality and provides diagnostic and prognostic information on many cardiovascular diseases such as in heart failure [15][16][17] . However, there is no information regarding its relationship with COVID-19 pneumonia.…”

mentioning

confidence: 99%

Prognostic Value of T wave Positivity in Lead aVR in COVID-19 Pneumonia

sivri,

ÖZDEMİR,

ÇELİK

et al. 2024

Preprint

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Background:T wave positivity in the lead aVR is a marker of ventricular repolarization abnormality and provides information on short and long-term cardiovascular mortality in patients who have heart failure, anterior myocardial infarction, and receive hemodialysis for various reasons. The aim of this study was to investigate the relationship between T wave positivity in the lead aVR on superficial ECG and mortality from COVID-19 pneumonia. Methods: This study retrospectively included 130 patients who were diagnosed with COVID-19 and treated as an outpatient or in the thoracic diseases ward in a single center between January 2021 and June 2021. All patients included in the study had clinical and radiological features and signs of COVID-19 pneumonia. The COVID-19 diagnosis of all patients was confirmed by polymerase chain reaction (PCR) studied from an oropharyngeal swab Results: A total of 130 patients were included in this study. Patients were divided into 2 groups: survived and deceased. There were 55 patients (with a mean age of 64.76-14.93 years, 58.18% male, 41.12% female) in the survived group, while there were 75 patients (with a mean age of 65-15 years, 58.67% male, 41.33% female) in the deceased group. The univariate and multivariate regression analyses showed that positive TAVR (OR: 5.151, 95% CI: 1.001-26.504, p: 0.0012), lactate dehydrogenase (LDH) (OR: 1.006, 95% CI: 1.001-1.010, p: 0.012) and D-dimer (OR:1.436, 95% CI: 1.115-1.848, p: 0.005) were independent risk factors for mortality Conclusions: positive TAaVR is useful in risk stratification for COVID-19 pneumonia mortality. KEY WORLD:Electrocardıographıa, positive TAaVR, COVID-19 pneumonia, mortality

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Lead aVR is a predictor for mortality in heart failure with preserved ejection fraction

Cited by 6 publications

References 24 publications

Prognostic Value of T-wave Positivity in Lead aVR in COVID-19 Pneumonia

Prognostic Value of T-wave Positivity in Lead aVR in COVID-19 Pneumonia

The prognostic significance of a positive or isoelectric T wave in lead aVR in patients with acute coronary syndrome and ischemic ECG changes in the presenting ECG - Long-term follow-up data of the TACOS study

Prognostic Value of T wave Positivity in Lead aVR in COVID-19 Pneumonia

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