Lead and cadmium concentrations in blood of people living near a copper smelter in Legnica, Poland

Andrzejak, Ryszard; Antonowicz, J.; Tomczyk, J; Lepetow, T.; Smolik, R

doi:10.1016/s0048-9697(05)80023-3

Cited by 7 publications

(10 citation statements)

References 4 publications

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“…2. As for the correlation between air and blood lead levels, preceding reports have shown conflicting results and for the copper smelters in particular, no detailed analysis for such a correlation has been performed [1][2][3][4][5][6][7][8][9] . Never the less the results of the present study suggest that workers in Mean blood lead level of workers in the anode department (25.7 ± 6.1 µg/dl) was significantly higher than that in any other three copper smelter departments and control (office) workers (Wilcoxon test: p<0.001).…”

Section: Discussionmentioning

confidence: 99%

“…In spite of the preceding reports on the elevated blood lead levels in copper smelters [1][2][3][4][5][6][7][8][9] , the Ordinance on Prevention of Lead Poisoning in Japan does not include copper smelting into its target job categories if the lead concentration in the raw materials is less than 3%. In general, copper ores contain 0.003 to 1.3% of lead 17) .…”

Section: Discussionmentioning

confidence: 99%

“…There have been a number of studies that have reported increased blood lead levels in copper smelter workers [1][2][3][4][5][6][7][8][9] . Lilis et al 1) reported that mean blood lead levels in copper smelter workers was 31.1 µg/dl.…”

Section: Introductionmentioning

confidence: 99%

“…Apparently workers in copper smelters are exposed to higher level of lead. Gagne et al 8) reported elevated lead levels in the soil of a residential district near a copper smelter in Canada, and Andrzejak et al 9) reported elevated air lead concentrations of a village near a copper smelter in Poland. However there has been no reported study concerning lead exposure in copper smelter workers in Japan.…”

Section: Introductionmentioning

confidence: 99%

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Blood Lead Levels in Copper Smelter Workers in Japan.

et al. 2000

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Lead exposure of workers in a Japanese copper smelter was assessed by determining lead levels in blood, air and flue cinder at the copper smelting processes. All the samples were analyzed for lead by atomic absorption spectrometry. Mean lead levels of air were highest at the anode department followed by the converter, smelter and blend departments. The mean level of blood lead of the workers in the anode department was also the highest among the four smelting departments. The mean blood lead levels of the workers in each department were positively correlated with their air lead levels (r=0.99, p<0.01). This study indicates therefore that workers in copper smelters have been exposed to lead in their workplace. Though this finding has already been reported in preceding studies, the Ordinance on Prevention of Lead Poisoning in Japan has not included copper smelter into its target job categories if their lead concentration in the raw material is less than 3%. The limitation of the present Ordinance which defines the targets by the types of job and not by the actual exposure, is discussed.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Blood Lead Levels in Copper Smelter Workers in Japan.

et al. 2000

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“…with bone marrow suppression. 4,5 Whereas clozapine has been shown to lead to hematopoietic effects, especially neutropenia and thrombocytopenia, olanzapine has been deemed as a safe alternative for patients who have had hematologic side effects from other antipsychotics. 2 The incidence of hematopoietic suppression, including leukopenia and thrombocytopenia, is lower with olanzapine than with clozapine, 2,3 but physicians should still be cautious when prescribing it to elderly patients.…”

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confidence: 99%

Thrombocytopenia and Spontaneous Intracranial Hemorrhage After Olanzapine Therapy

Cruz¹,

Danoff²

2017

Journal of Osteopathic Medicine

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The use of atypical antipsychotics in the United States has increased over the past decade, since atypical antipsychotics such as olanzapine and clozapine were introduced. Of the adverse effects associated with olanzapine, bone marrow suppression is one of the most common, but spontaneous intracranial hemorrhage secondary to thrombocytopenia is rare. The present case report describes an 88-year-old man who presented with an intracranial hemorrhage after taking olanzapine for 2 weeks. This case emphasizes the importance of monitoring the potential adverse effects associated with olanzapine and other antipsychotics, especially in elderly patients.

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