Le synovialosarcome de la sphère oto-rhino-laryngée: une localisation rare: à propos de deux cas

Kouhen, Fadila; Afif, Mohammed; Benhmidou, Naoual; Rais, Fadoua; Kabous, M. El; Khmou, Mouna; Cherradi, Nadia; Majjaoui, Sanaa El; Elkacemi, H.; Kebdani, Tayeb; Benjaafar, Noureddine

doi:10.11604/pamj.2015.20.232.6225

Cited by 3 publications

(4 citation statements)

References 9 publications

(15 reference statements)

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“…In this case, at the reevaluation, it was noticed an increasing mass size, without any signs of improvement and new symptoms such as dyspnea and odynophagia. These findings prompted the patient's referral to the emergency room (ER), leading to a workup that allowed for the diagnosis to be anticipated by three months, compared to the literature [ 9 ]. Considering the diagnosis of sarcomas, a delay in diagnosis is frequent due to their rarity and diverse clinical presentations, as shown in the clinical case by Algargaz et al [ 10 ].…”

Section: Discussionmentioning

confidence: 99%

“…In the literature, the standard treatment is the complete excision of the tumor with radiotherapy playing an important role in the presence of positive or marginal margins [ 11 ]. Nevertheless, as there are no standard margins or radiation dose, different approaches have been performed, as described by Kouhen et al, where the two presented cases underwent surgery followed by radiotherapy with different radiation doses, and neither of the patients received chemotherapy treatment [ 9 ]. This enhances the importance of further investigation to define standardized treatment.…”

Section: Discussionmentioning

confidence: 99%

“…In fact, regarding synovial sarcomas, the mean duration of symptoms before the correct diagnosis is approximately two years. However, considering the head and neck the diagnosis was accomplished 20 months earlier, representing a four-month gap between the appearance of the first symptoms and the diagnosis [ 9 ]. While sarcoma can develop in any anatomical part, the majority of them involve the extremities, with only 9% occurring in the head and neck region.…”

Section: Introductionmentioning

confidence: 99%

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Unveiling the Mystery: A Case Report on Oropharyngeal Synovial Sarcoma

Gonçalves,

Soares,

Ribeiro

et al. 2023

Cureus

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Synovial sarcoma, originating from mesenchymal cells, represents a rare and aggressive sarcoma subtype. This case report describes a rare occurrence of synovial sarcoma in the soft palate, with only a few cases described in the literature. A 38-year-old male presented with a painless mass on the soft palate, which raised suspicion of an abscess and emphasized the importance of considering malignancy in persistent or progressive soft tissue masses, even in atypical anatomical locations. The diagnostic workup, including imaging modalities such as maxillofacial computed tomography (CT) scan, magnetic resonance imaging (MRI), and positron emission tomography-fluorodeoxyglucose (PET-FDG) scan, played a crucial role in confirming the diagnosis and assessing disease extension. The standard treatment is the complete excision of the tumor. Nevertheless, when it comes to tumors located in the head and neck region, defining standardized margins proves to be a challenge. Radiotherapy can play an important role, particularly in those with tumors larger than 5 cm or positive margins. While chemotherapy offers certain advantages, its application remains a subject of controversy despite its potential benefits. Timely referral and multidisciplinary management are essential in optimizing patient outcomes. Although synovial sarcoma poses diagnostic and therapeutic challenges, advances in diagnostic techniques and personalized medicine offer hope for improved outcomes.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Unveiling the Mystery: A Case Report on Oropharyngeal Synovial Sarcoma

Gonçalves,

Soares,

Ribeiro

et al. 2023

Cureus

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“…Other locations, such as head, neck, abdomen wall, lung, and kidney, have also been reported. 4 - 7 The orbit is a rare location for primary SS, with only 5 previously reported cases according to the research results from PubMed. 2 , 8 - 11 …”

Section: Discussionmentioning

confidence: 99%

Primary Synovial Sarcoma of the Orbit

Chen

2017

Ophthalmol Eye Dis

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Purpose:To describe the clinical, pathological, and immunohistochemical characteristics and therapies of a rare case of primary synovial sarcoma in the orbit.Design:Retrospective interventional case report.Participant:A 6-year-old girl with pathologically proven synovial sarcoma in the orbit. The diagnosis was confirmed by immunohistochemistry.Methods:The patient was treated with right lateral orbital and right temporal tumor resection, followed by chemotherapy. She was followed up every 3 months for 1 year.Results:The tumor was excised, and the patient received 5 courses of chemotherapy. She did well during the initial first-year follow-up with no recurrent signs.Conclusions:We reported the sixth case of primary synovial sarcoma in the orbit and the first case of a 6-year-old girl.

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Synovial Sarcoma of the Parotid Gland A Case Report and Review of Literature

Rochdi

Rizkou²,

Oulghoul³

et al. 2023

EJMED

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The clinicopathologic characteristics of the head and neck Synovial sarcoma are scant. The parotid gland localization of this unusual neoplasm of mesenchymal derivation is most likely to be misdiagnosed as primary mesenchymal, myoepithelial, or metastatic neoplasm. We report a case of synovial sarcoma in the parotid gland in a young enfant that underwent total resection of the parotid tumor after the failure of the initial chemotherapy. Adding to many studies, to determine the radiologic and histologic features that lend a hand in the proper diagnostic, as well as highlighting the prognostic factors for a favorable outcome.

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Le synovialosarcome de la sphère oto-rhino-laryngée: une localisation rare: à propos de deux cas

Cited by 3 publications

References 9 publications

Unveiling the Mystery: A Case Report on Oropharyngeal Synovial Sarcoma

Unveiling the Mystery: A Case Report on Oropharyngeal Synovial Sarcoma

Primary Synovial Sarcoma of the Orbit

Synovial Sarcoma of the Parotid Gland A Case Report and Review of Literature

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