Le rôle de l’odontologiste dans le cadre du syndrome SAPHO : cas cliniques et revue de la littérature des signes oro-faciaux

Abstract

Résumé -Introduction :Le syndrome SAPHO est une affection rare associant des signes ostéo-articulaires et cutanés. C'est une maladie douloureuse et invalidante atteignant plus fréquemment les femmes que les hommes. Les signes cliniques au niveau de la sphère oro-faciale sont rarement évoqués. Observations : Les signes cliniques oro-faciaux évocateurs de ce syndrome ont été rapportés chez un homme de 50 ans et la prise en charge odontotologique d'une femme de 39 ans atteinte d'un syndrome SAPHO est décrite. Discussion : L'odontologiste peut être amené à diagnostiquer un syndrome SAPHO devant certains signes oro-faciaux évocateurs qui font l'objet d'une revue de la littérature. De plus, il apporte sa contribution dans la prise en charge des lésions oro-faciales liées directement au syndrome ou indirectement mais dont le traitement nécessite des précautions particulières ainsi que par la recherche de foyers infectieux avant l'instauration des traitements du syndrome SAPHO. Conclusion : L'odontologiste doit jouer un rôle actif dans la prise en charge du syndrome SAPHO tant sur le versant diagnostique que thérapeutique.Abstract -The role of the dentist in SAPHO syndrome: case reports and literature review of orofacial manifestations. Introduction: SAPHO syndrome is a rare disorder combining osteoarticular and cutaneous signs. It is a painful and disabling disease, which affects women more frequently than men. Orofacial manifestations are rarely reported. Observation: The first case presents orofacial manifestations suggestive of SAPHO syndrome involving a 50-year-old patient, and the second case shows a 39-year-old woman affected by SAPHO syndrome treated in a department of dentistry. Discussion: Certain orofacial manifestations can suggest a diagnosis of SAPHO syndrome, which are the subject of a literature review. The dentist contributes to the management of the orofacial manifestations directly linked to the syndrome or indirectly, for which the treatment requires particular precautions and searching for foci of infection before the commencement of the SAPHO syndrome treatments. Conclusion: The dentist must be allowed to play an active role in the management of SAPHO syndrome, in both the diagnostic and therapeutic aspects.

Contribution of Bone Scintigraphy in the Diagnosis of a Case of SAPHO in the Nuclear Medicine Department of Idrissa Pouye General Hospital (Dakar, Senegal)

“…Ghomari reported a case of SAPHO in a 56-year-old patient [4]. Occurrence in children is rare, but possible [1] [3].…”

“…Female predilection is also described in the literature [3] [4] [11]. However, according to I. Gharsallah [1] and Assia Haddouche [7], it affects both sexes equally, with a sex ratio close to 1.…”

“…Biological blood tests are especially useful for diagnosing pathologies associated with the syndrome, such as chronic inflammatory bowel disease [3].…”

“…SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome is a rare entity that combines a heterogeneous set of cutaneous and osteoarticular manifestations, with a common aseptic inflammatory process. It associates osteoarticular disorders (synovitis, hyperostosis, osteitis), essentially sternocostoclavicular, with skin abnormalities (acne, pustulosis) [1] [2] [3]. SAPHO syndrome is known as "Skibo-disease" (short for skin-bone), i.e.…”