Le cancer gastrique : aspects épidémiologiques au Maroc

Fadlouallah, M.; Krami, H.; Errabih, I.; Benzzoubeir, N.; Ouazzani, L.; Ouazzani, H.

doi:10.1007/s12558-014-0322-4

Cited by 5 publications

(4 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We should underline that several studies reported a masculine predominance supporting our findings (8)(9)(10).…”

Section: Discussionsupporting

confidence: 91%

“…Some African authors reported in their studies that the antropyloric site was encountered in 52.3% and 74.11% of the patients respectively contrasting our results where the frequency of this location was reduced (9.1%) (8,17). According to Daouda et al, 79% gastric tumors were located at the antral and cardiac level, confirming our results concerning the antral site (40.9%) and opposing those related to the cardiac location (7.3%) (20).…”

Section: The Rate Of Gastrointestinal Bleeding Was Lower Than Melloukcontrasting

confidence: 99%

See 1 more Smart Citation

Epidemiological profile of gastric cancer in the northwestern region of Algeria: about 116 cases

Fehim

Bouhaous

Diaf

et al. 2017

J. Gastrointest. Oncol.

View full text Add to dashboard Cite

Background: Gastric cancer (GC) remains a public health issue despite the global incidence decrease over the last decades. GC is the third leading cause of cancer-related death worldwide and stills of poor prognosis due to its late detection. The overall objective of our study was to describe the epidemiological, clinical, and histopathological aspects of stomach cancer. However, the specific purpose was to determine the gastric precancerous lesions among patients with histologically confirmed GC admitted at the gastroenterology department of the University Hospital of Sidi-Bel-Abbes city, Algeria.Methods: We retrospectively analyzed the patients' medical records admitted from 2010 to 2015. Intended for the statistical analysis of the enrolled data, we executed Student t-test and Chi-squared test, significance level was set at 5%. Histologic evidence objectified the biopsies performed during endoscopy; Hematoxylin and Eosin staining as well as the slides interpretation were executed at the level of the pathology department as a routine examination.Results: 116 cases of GC were recorded. The mean age of the whole studied cohort was 58.96±14.75 years. We reported a sex ratio of 1.36 with a peak frequency observed in male gender (57.76%).Gastric precancerous lesions, as well as tumor histology, and topography were revealed. In our context, adenocarcinoma was significantly higher among male patients and linitis plastica was expressively related to female gender (P=0.01).Conclusions: Management of gastric precancerous lesions additionally to early diagnosis represent effective preventive and therapeutic methods of GC.

show abstract

“…We should underline that several studies reported a masculine predominance supporting our findings (8)(9)(10).…”

Section: Discussionsupporting

confidence: 91%

Section: The Rate Of Gastrointestinal Bleeding Was Lower Than Melloukcontrasting

confidence: 99%

Epidemiological profile of gastric cancer in the northwestern region of Algeria: about 116 cases

Fehim

Bouhaous

Diaf

et al. 2017

J. Gastrointest. Oncol.

View full text Add to dashboard Cite

show abstract

“…ln several studies, gastric cancer affects more men than women, which is consistent with our finding of 1.78 (male-tofemale) (Fadlouallah et al, 2015 andFerlay et al,2021). As well as this, it has been suggested that gender differences reflect physiological differences; estrogens have been shown to protect women from gastric cancer (Sheh et al, 2011 andDerakhshan et al, 2009).…”

Section: Statistical Analysessupporting

confidence: 91%

Epidemiological, Clinical, and Pathological Characteristics of Gastric Carcinoma in The Northwest Region of Algeria: A Single Center Study

Cherifi

Haoud²,

Mokhtar³

et al. 2023

Egyptian Academic Journal of Biological Sciences. C, Physiology

View full text Add to dashboard Cite

Introduction: Cancer of the stomach is a serious public health issue due to its frequency and severity. It is one of the most common causes of cancer-related death for both sexes and is a major contributor to the global burden of disease. To better understand the epidemiological, clinical, and pathological characteristics of gastric cancer in the Western Algerian region Sidi Bel Abbes, our study aimed to investigate the prevalence, risk factors, and clinical outcomes of gastric cancer in this region.Methods: The medical records of 131 patients with gastric cancer in the Sidi Bel Abbes region between January 2015 and December 2019 were reviewed retrospectively in order to gain insight into the epidemiology of gastric cancer in the region.Result: The results of this statistical analysis indicate that there is a male predominance in the cases studied and that the average age of the patients is 61.069 years. Histologically, carcinoma is the most common histological type (87.7%). 77.1% of cases were diagnosed in stages III and IV of TNM, and 46.6% of cases were found in the pyloric antrum. 38.2% of the cases had atrophic chronic gastritis as a precancerous lesion, and 16.8% had acute or chronic gastritis. Conclusion:The diagnosis of gastric cancer is often made at a late stage with a poor prognosis. However, in order to develop strategies for prevention and early detection, extensive research is still needed to identify the risk factors for gastric cancer.

show abstract

“…In contrast, our rate is different from that found by another Moroccan study conducted in the city of Fes, where the prevalence of the cagA gene was 69% 23 . This difference can be explained by the high incidence of GC encountered in this city compared to our city (Casablanca), as reported by the study done by Fadloullah et al 24 . In addition, the same observations have been reported in several countries, such as Mexico (43 and 90%) and Turkey (52 and 94%) 25 , 26 .…”

Section: Discussionmentioning

confidence: 48%

The EPIYA-ABCC motif of Helicobacter pylori cagA gene and gastric carcinogenesis in Casablanca population

Jouimyi¹,

Bounder²,

Boura³

et al. 2022

Afr H. Sci.

View full text Add to dashboard Cite

Background: H. pylori infection induce atrophic gastritis (AG) and intestinal metaplasia (IM) that can lead to gastric cancer (GC). The severity of gastric lesions is related to H. pylori genetic diversity. The oncogenic potential of H. pylori cagA virulence factor is linked to its high polymorphic EPIYA motifs. Objectives: Our aim was to evaluate the association of EPIYA motifs with the risk of AG and IM in Casablanca population. Methods: A total of 210 patients suffering from gastric lesions (chronic gastritis, AG, and IM) was enrolled. H. pylori infection and the type of lesions were diagnosed by ureC PCR and histological examination, respectively. Detection of the cagA gene, and the type of EPIYA motifs, were carried out by PCR Results: The prevalence of H. pylori and cagA gene was 95% and 37%, respectively. CagA-positive strains were associated with the risk of IM. The EPIYA motifs detected were: EPIYA-ABC (58%), EPIYA-ABCC (22%), and EPIYA-AB (20%). The EPIYA-ABCC motif was associated with the risk of IM (p-value = 0.007), compared to AG (p-value = 0.28). Conclusion: The EPIYA-ABCC motif might be a useful marker for the identification of patients at high risk of developing IM that can lead to GC. Keywords: cagA gene; EPIYA motifs; gastric carcinogenesis.

show abstract

Le cancer gastrique : aspects épidémiologiques au Maroc

Cited by 5 publications

References 19 publications

Epidemiological profile of gastric cancer in the northwestern region of Algeria: about 116 cases

Epidemiological profile of gastric cancer in the northwestern region of Algeria: about 116 cases

Epidemiological, Clinical, and Pathological Characteristics of Gastric Carcinoma in The Northwest Region of Algeria: A Single Center Study

The EPIYA-ABCC motif of Helicobacter pylori cagA gene and gastric carcinogenesis in Casablanca population

Contact Info

Product

Resources

About