Layered Double Hydroxides as Promising Excipients for Drug Delivery Purposes

Sousa, Aretuza; Santos, Widson Michael dos; Souza, Myla Lôbo de; Silva, Laysa Creusa Paes Barreto Barros; Yun, Adriana Eun He Koo; Aguilera, Cindy Siqueira Britto; Chagas, Beatriz de França; Rolim, Larissa Araújo; Silva, Rosali Maria Ferreira da; Neto, Pedró José Rolim

doi:10.1016/j.ejps.2021.105922

Cited by 29 publications

(13 citation statements)

References 85 publications

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“…In this context, an organic-inorganic hybrid state-of-the-art material, e.g., 2,2 ,7,7 -tetrakis-(N,N-di-p-methoxy-phenyl-amine)-9,9 -spiro-bifluorene (spiro-OMeTAD) has mainly been used so far in different research works due to its enhanced PV performance, amorphous nature, and optimal solubility in various organic solvents [51,60,162,[248][249][250]. Furthermore, poly(tri-arylamine, a polymeric organic material, has been introduced by many researchers to yield high certified PCEs in regular planar structured devices [155,167,[251][252][253]. However, in terms of stability, both materials have failed to gratify the researchers due to their various intrinsic properties.…”

Section: Improvement and Modification Of Hole Transport Layers (Htls)mentioning

confidence: 99%

Recent Criterion on Stability Enhancement of Perovskite Solar Cells

et al. 2022

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Perovskite solar cells (PSCs) have captured the attention of the global energy research community in recent years by showing an exponential augmentation in their performance and stability. The supremacy of the light-harvesting efficiency and wider band gap of perovskite sensitizers have led to these devices being compared with the most outstanding rival silicon-based solar cells. Nevertheless, there are some issues such as their poor lifetime stability, considerable J–V hysteresis, and the toxicity of the conventional constituent materials which restrict their prevalence in the marketplace. The poor stability of PSCs with regard to humidity, UV radiation, oxygen and heat especially limits their industrial application. This review focuses on the in-depth studies of different direct and indirect parameters of PSC device instability. The mechanism for device degradation for several parameters and the complementary materials showing promising results are systematically analyzed. The main objective of this work is to review the effectual strategies of enhancing the stability of PSCs. Several important factors such as material engineering, novel device structure design, hole-transporting materials (HTMs), electron-transporting materials (ETMs), electrode materials preparation, and encapsulation methods that need to be taken care of in order to improve the stability of PSCs are discussed extensively. Conclusively, this review discusses some opportunities for the commercialization of PSCs with high efficiency and stability.

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Section: Improvement and Modification Of Hole Transport Layers (Htls)mentioning

confidence: 99%

Recent Criterion on Stability Enhancement of Perovskite Solar Cells

et al. 2022

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“…However, this combination must consider the octahedral coordination and the ionic radius (preferably between 0.50 and 0.74 Å), as distortions may occur with the use of cations. In addition, it is necessary to consider the relationship between the size and charge of the interlayer anion so that it is possible to balance the positive charges of the layer homogeneously [ 32 ].…”

Section: Ldhs Physicochemical Characteristicsmentioning

confidence: 99%

“…Thus, the versatility of the chemical composition and nanostructure of LDHs establish them as promising adsorbents against a wide variety of pollutants. The most attractive properties of LDHs are the chemical compositions according to the metals used, the space between layers, and the high surface capable of adsorbing bioactive substances, which are dominated by the synthesis conditions [ 32 ]. All the above can be tuned on demand based on the synthetic approach/protocol.…”

Section: Ldhs Physicochemical Characteristicsmentioning

confidence: 99%

Layered Double Hydroxides as Rising-Star Adsorbents for Water Purification: A Brief Discussion

et al. 2022

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Within the frame of this article, briefly but comprehensively, we present the existing knowledge, perspectives, and challenges for the utilization of Layered Double Hydroxides (LDHs) as adsorbents against a plethora of pollutants in aquatic matrixes. The use of LDHs as adsorbents was established by considering their significant physicochemical features, including their textural, structural, morphological, and chemical composition, as well as their method of synthesis, followed by their advantages and disadvantages as remediation media. The utilization of LDHs towards the adsorptive removal of dyes, metals, oxyanions, and emerging pollutants is critically reviewed, while all the reported kinds of interactions that gather the removal are collectively presented. Finally, future perspectives on the topic are discussed. It is expected that this discussion will encourage researchers in the area to seek new ideas for the design, development, and applications of novel LDHs-based nanomaterials as selective adsorbents, and hence to further explore the potential of their utilization also for analytic approaches to detect and monitor various pollutants.

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“…They are currently attracting more technological interest due to their outstanding properties such as facile synthesis, unique structure, unvarying distribution of diverse metal cations in the brucite layer, surface hydroxyl groups, high tunability, intercalated anions with interlamellar spaces, excellent chemical stability, and the ability to intercalate diverse varieties of anions (inorganic, organic, biomolecules, and even genes) [ 3 ]. Due to its tunability, LDH is acclaimed in a variety of technological applications such as photoluminescence [ 4 ], sensors [ 5 ], drug delivery [ 6 ], cosmetics [ 7 ], antimicrobial materials [ 8 ], catalysts [ 9 ], and supercapacitors [ 10 ]. However, LDH is more applied for energy storage applications because of the synergistic effects of two or more metals involved during its preparation resulting in higher theoretical specific capacitance compared to single counterparts [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

Investigating the Impact of the Washing Steps of Layered Double Hydroxides (LDH) on the Electrochemical Performance

et al. 2022

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The washing of layered double hydroxides (LDH) material is mostly purposed to discard the unreacted products after the reaction has been completed. However, this study demonstrated that the washing stage can also be targeted to optimise the electrochemical performance of LDH by using an appropriate solvent. Solvents, namely, ethanol, acetone, and an ethanol–acetone solution (2:1) were used for the washing of LDH and the impacts thereof on the structural, physical, chemical, morphological, and electrochemical properties were investigated. Using Williamson–Hall analysis, we observed modifications on the crystalline domain. The specific surface area and pore parameters for all the samples were also differently affected. The Fourier transform infrared (FTIR) measurements displayed evident changes in the basic sites. The electrochemical performances of samples were analysed. The sample washed with the ethanol–acetone solution exhibited a specific capacitance of 1807.26 Fg−1 at 10 mVs−1, which is higher than that of other samples as well as low internal resistance compared to its counterpart. This demonstrates that the use of an appropriate solvent during the washing stage of LDH affects the electrochemical properties.

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Layered Double Hydroxides as Promising Excipients for Drug Delivery Purposes

Cited by 29 publications

References 85 publications

Recent Criterion on Stability Enhancement of Perovskite Solar Cells

Recent Criterion on Stability Enhancement of Perovskite Solar Cells

Layered Double Hydroxides as Rising-Star Adsorbents for Water Purification: A Brief Discussion

Investigating the Impact of the Washing Steps of Layered Double Hydroxides (LDH) on the Electrochemical Performance

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