Late Seroma after Breast Augmentation with Silicone Prostheses: A Case Report

Managing Late Periprosthetic Fluid Collections (Seroma) in Patients with Breast Implants: A Consensus Panel Recommendation and Review of the Literature

“…15 The cause and pathophysiology of late periprosthetic fluid collection is unknown but may include vascular or lymphatic leakage that occurs in comorbid conditions such as inflammation from a bacterial infection, hematoma or other trauma, idiopathic reasons related to breast augmentation or reconstructive surgery, cancer, or lymphoproliferative disorders. 11 Synovial metaplasia resulting from mechanical shear forces, or sliding surfaces generated by micromotions between the implant and the surrounding tissue, may also give rise to periprosthetic fluid collections. 9,14 Late periprosthetic fluid collection in the presence of breast implants has also been reported in association with malignancy.…”

“…Patients diagnosed with late seroma presented with swelling or breast asymmetry, often with breast tenderness, and with or without palpable fluid collection around the breast. [7][8][9][10][11][12][13][14] In addition, at surgical exploration, some patients were found to have a double capsule, defined as a dual layer of circumferential fibrous capsular adherence (the inner layer adherent to the device and the outer layer adherent to tissue) with a potential space between each layer. 14 Seroma in the early postoperative period is a common occurrence after surgical procedures that create a dead space but is infrequently reported as a late complication (Ն1 year after surgery).…”

“…[7][8][9][10][11][12][13][14] This work group was convened, in the absence of a controlled, clinical trial-based evaluation, to examine the available literature on the development of late periprosthetic fluid collection in patients with breast implants, and to develop a consensus and best practice consensus algorithm for evaluation and management. This collected opinion should not suggest a standard of care.…”

Adverse reactions to injectable soft tissue fillers

“…191,[200][201][202] Other complications of solid silicone implants in deeper tissues are rare, but the literature shows descriptions of bone erosion, infection, seroma, and implant extrusion. 203 Pulmonary embolism, acute pneumonitis, and granulomatous hepatitis are very rare systemic complications after the fraudulent use of large amounts of liquid silicone in transsexual patients. 204,205 Histopathologic findings in local reactions to implants of silicone are variable depending mainly on the form of the injected silicone (liquid, gel, or solid elastomer type) and the amount of product implanted in the tissues.…”

Late Seromas after Breast Implants

“…The first description of seroma following breast implant surgery appears to have been in 1991, 6 and for the following two decades, only a few surgeons have added their isolated series. [7][8][9][10][11][12][13][14] Several themes have been prevalent. First, late seromas are remarkably rare.…”