Late Seizure Following Ingestion of Vicks VapoRub

Ruha, Anne‐Michelle; Graeme, Kimberlie A.; Field, Adam G.

doi:10.1111/j.1553-2712.2003.tb00059.x

Cited by 21 publications

(13 citation statements)

References 2 publications

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“…In another case report, a 4-year-old girl developed convulsions 9 hours after ingesting Vicks VapoRub Ointment. However, she had been found in bed lying in her vomitus at approximately 5 hours after the estimated time of ingestion; the time of onset of the first symptoms is unknown (50). In a case series of 19 patients (level 4), the onset of effects occurred up to 125 minutes after ingestion (15).…”

Section: Onset Of Effects After Acute Ingestionsmentioning

confidence: 99%

“…There were a number of anecdotal reports describing temporal improvement in convulsions, agitation, or excessive neuromuscular activity in patients with camphor toxicity after the administration of benzodiazepines or barbiturates (6,7,9,14,(16)(17)(18)22,25,26,(48)(49)(50)60,62,63,73,74). There was a single report of some improvement after phenytoin administration (62).…”

Section: Anticonvulsantsmentioning

confidence: 99%

“…It should also be noted that many patients with toxicity continued to deteriorate after symptom onset, hospital presentation, and/or decontamination, usually over the course of several hours (7,12,20,40,47,49,50). Most patients without complications recovered within 24 hours.…”

Section: Onset Of Effects After Acute Ingestionsmentioning

confidence: 99%

“…There were two level 4 articles reporting three cases with data on dose-toxicity relationships for Vicks VapoRub Ointment, a product containing 4.8% camphor (6,50). Between them, the lowest dose associated with severe toxicity was an ingestion of approximately 1 tablespoonful (equivalent to 0.7 g camphor-41 mg/kg) by a 3-year-old girl who developed vomiting, confusion, and convulsions (6).…”

Section: Vicks Vaporub Ointmentmentioning

confidence: 99%

See 3 more Smart Citations

Camphor Poisoning: an Evidence-Based Practice Guideline for Out-of-Hospital Management

Manoguerra

Erdman

Wax

et al. 2006

Clinical Toxicology

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Section: Onset Of Effects After Acute Ingestionsmentioning

confidence: 99%

Section: Anticonvulsantsmentioning

confidence: 99%

Section: Onset Of Effects After Acute Ingestionsmentioning

confidence: 99%

Section: Vicks Vaporub Ointmentmentioning

confidence: 99%

See 2 more Smart Citations

Camphor Poisoning: an Evidence-Based Practice Guideline for Out-of-Hospital Management

Manoguerra

Erdman

Wax

et al. 2006

Clinical Toxicology

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“…Within a period of 5 to 15 minutes, patients commonly complain of mucus membrane irritation, nausea, vomiting, and abdominal pain. Generalized tonic-clonic convulsions are often the first sign of significant toxicity and can occur soon after ingestion [13]. Central nervous system depression is commonly seen, such as headache, dizziness, confusion, agitation, anxiety, hallucinations, myoclonus, and hyperreflexia.…”

Section: Therapeutic Usementioning

confidence: 99%

Unique Case with Seizures after Prolonged Use of Camphor Crème in Elderly Patient

Niko¹,

Snezhana²

2012

J Clin Toxicol

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Camphor is a pleasant smelling cyclic ketone of the hydro aromatic terpene group. The mechanism by which camphor produces toxicity is unknown. Within a period of 5 to 15 minutes, patients commonly complain of mucus membrane irritation, nausea, vomiting, and abdominal pain. Generalized tonic-clonic convulsions are often the first sign of significant toxicity and can occur soon after ingestion. Central nervous system depression is commonly seen, such as headache, dizziness, confusion, agitation, anxiety, hallucinations, myoclonus, and hyperreflexia.The aim of the study is to show a unique case of generalized tonic-clonic convulsions, after 1 week of dermal applications of camphor crème in elderly patient. Case Report66-year old female was brought to the University Clinic for Toxicology in Skopje, with status epilepticus, after several generalized tonic-clonic seizures. At arrival, the patient was somnolent, with heavy headache, hypotensive (14/9 kPa), with partial amnesia, relax muscles, small amount of blood in mouth and specific odour. Five minutes later, during standard examination, the patient developed another generalized tonic-clonic seizure. An amount of 10 ml i.v. diazepam was applied to stabilize the patient, and a few minutes later the patient woke up. Heteroanamnesis taken from her husband showed that she had another similar convulsion ten days ago. EEG, CT and MRI made previously, did not show any abnormalities. The specific smelt, repeated seizures and especially the dermal application of Kamfart crème, made the suspicion of poisoning with camphor. The toxicological examination showed a positive result. After excluding the camphor crème, the patient didn't manifest any seizures.

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Eucalyptus oil inhalation–induced seizure: A novel, underrecognized, preventable cause of acute symptomatic seizure

Mathew

Kamath

Kumar³

et al. 2017

Epilepsia Open

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SummaryEucalyptus oil (EO) is an essential oil that is widely used across the globe as an over‐the‐counter remedy for common ailments. EO‐induced seizure (EOIS) has not been recognized as an entity, and physicians rarely ask the history of exposure to eucalyptus oil when seeing a patient with first episode of seizure. Here we report 10 cases of EO inhalation–induced seizures seen over the past 2 years in three tertiary care hospitals. Eight patients had GTCS and two had CPS. We aim to raise awareness of seizures induced by exposure to eucalyptus oil.

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Late Seizure Following Ingestion of Vicks VapoRub

Cited by 21 publications

References 2 publications

Camphor Poisoning: an Evidence-Based Practice Guideline for Out-of-Hospital Management

Camphor Poisoning: an Evidence-Based Practice Guideline for Out-of-Hospital Management

Unique Case with Seizures after Prolonged Use of Camphor Crème in Elderly Patient

Eucalyptus oil inhalation–induced seizure: A novel, underrecognized, preventable cause of acute symptomatic seizure

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