Late-onset Behçet’s disease: demographic, clinical, and ocular features

Sungur, Gülten; Hazırolan, Dicle; Hekimoğlu, Emre; Kasim, Remzi; Duman, Sunay

doi:10.1007/s00417-010-1399-5

Cited by 34 publications

(16 citation statements)

References 14 publications

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“…The clinical courses of childhood-onset Behçet's disease and late-onset Behçet's disease are relatively benign 16,21,24,27,28. The average time between the initial appearance of the first major symptom, usually oral ulcerations, and the development of a second major symptom in children is 8.8 years 27.…”

Section: Epidemiologymentioning

confidence: 99%

New Insights in the Clinical Understanding of Behçet's Disease

2012

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Behçet's disease is a chronic relapsing multisystemic inflammatory disorder characterized by four major symptoms (oral aphthous ulcers, genital ulcers, skin lesions, and ocular lesions) and occasionally by five minor symptoms (arthritis, gastrointestinal ulcers, epididymitis, vascular lesions, and central nervous system symptoms). Although the etiology of Behçet's disease is still unknown, there have been recent advances in immunopathogenic studies, genome-wide association studies, animal models, diagnostic markers, and new biological agents. These advances have improved the clinical understanding of Behçet's disease and have enabled us to develop new treatment strategies for this intractable disease, which remains one of the leading causes of blindness.

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Section: Epidemiologymentioning

confidence: 99%

New Insights in the Clinical Understanding of Behçet's Disease

2012

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“…Geç başlangıçlı BH'nın (40 yaş ve üzeri) sık-lığı Sungur ve ark.ları [20] tarafından %3,7 olarak bildirilmiştir. Çalışmamızda 17 (%4,3) olgunun tanı anında 40 yaş ve üzerinde olduğu görüldü.…”

Section: Discussionunclassified

“…Juvenil olgulara benzer şekilde oküler tutulum olanlar daha önce tanı almış idi. Sungur ve ark.ları çalışmaların-da olgularının %61,9'nda üveit tespit ederken en sık olarak anterior üveit izlemişlerdir [20]. Çalışmamıza benzer şekilde erkek ve kadın oranını eşit olarak bulmuşlardır.…”

Section: Discussionunclassified

Demographic characteristics and ocular involvement in Behçet patients in Southeast Anatolia

Türkçü

Yüksel²,

Uçmak³

et al. 2013

J Clin Exp Invest

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Objective: The aim of this study was to evaluate the demographic characteristics of Behcet's disease (BD) patients with and without ocular involvement. Methods:In this retrospective study BD patients followed up between 2009 and 2013 years in ophthalmology and dermatology clinics were reviewed. Patients were divided into 2 groups according to the ocular involvement as ocular or non-ocular BD. For each patient, age of onset, gender, family history, and systemic involvement were examined. The frequency of these data was analyzed. Results:Of the 295 patients 177 were ocular BD and 118 were non-ocular BD. Ocular involvement were seen more frequently in male patients than in females. There was no change between the groups in terms of age at onset of the disease, a history of thrombophlebitis or gastrointestinal, pulmonary and joint involvement. Pathergy test positivity and the presence of genital ulcers had more frequent in non-ocular BD. Conclusion:In this study clinical and demographic characteristics of ocular and non-ocular BD patients in the Southeast Anatolian Region of Turkey were presented. A similar study was not performed previously in our region therefore we believe that those data will be useful for diagnosis and follow-up of BD patients. J Clin Exp Invest 2013; 4 (3): 339-342

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“…As principais complicações da doença que acarretam perda da AV descritas na literatura são catarata, neuropatia óptica glaucomatosa e isquêmica (23) , oclusões vasculares e alterações retinianas como edema e atrofia (8,24) . No presente estudo verificou-se também como complicações mais frequentes da doença crônica o estreitamento vascular oclusivo, catarata, neuropatias ópticas e membrana epirretiniana.…”

Section: Discussionunclassified

Avaliação estrutural do polo posterior em pacientes com doença de Behçet

Corrêa¹,

Arantes²,

Lima³

et al. 2011

Arq. Bras. Oftalmol.

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Número do Projeto e Instituição responsável pelo parecer do Comitê de Ética em Pesquisa: Nº 1661/10 INTRODUÇÃOA doença de Behçet (DB), descrita em 1937 pelo dermatologista turco Hulusi Behçet, é uma desordem crônica multissistêmica com inflamação recorrente de etiologia desconhecida, provavelmente mediada por imunocomplexos(1) e de predisposição genética devido à associação com o grupo de HLA B 51. Apresenta maior prevalência em países do Mediterrâneo e Japão.A doença é diagnosticada pela presença de úlceras orais recorrentes acrescidas de pelo menos dois dos seguintes sinais: úlceras

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Late-onset Behçet’s disease: demographic, clinical, and ocular features

Cited by 34 publications

References 14 publications

New Insights in the Clinical Understanding of Behçet's Disease

New Insights in the Clinical Understanding of Behçet's Disease

Demographic characteristics and ocular involvement in Behçet patients in Southeast Anatolia

Avaliação estrutural do polo posterior em pacientes com doença de Behçet

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