Late Entry into HIV Care: Estimated Impact on AIDS Mortality Rates in Brazil, 2003–2006

Grangeiro, Alexandre; Escuder, Maria Mercedes Loureiro; Menezes, Paulo Rossi; Alencar, Rosa; Castilho, Euclides Ayres de

doi:10.1371/journal.pone.0014585

Cited by 58 publications

(70 citation statements)

References 41 publications

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“…Late presenters in Brazil tend to be men over age 40 (25) . They are often ill, have a 50-fold increase in their mortality risk (26) , and are less likely to respond to treatment when initiated (27) . (28) .…”

Section: Future Perspectivesmentioning

confidence: 99%

HIV/AIDS epidemic in the State of Amazonas: characteristics and trends from 2001 to 2012

Oliveira

Benzaken

Saraceni

et al. 2015

Rev. Soc. Bras. Med. Trop.

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70www.scielo.br/rsbmt I www.rsbmt.org.br Revista da Sociedade Brasileira de Medicina Tropical 48(Suppl I):70-78, 2015http://dx.doi. org/10.1590/0037-8682-0121-2013 Review Article ABSTRACT A scoping review was conducted to describe the epidemiological characteristics of the human immunodefi ciency virus/acquired immunodefi ciency syndrome (HIV/AIDS) epidemic in the State of Amazonas, Brazil, from 2001 to 2012, and temporary patterns were estimated from surveillance data. The results suggest that in its third decade, the Amazon HIV/AIDS epidemic is far from being stabilized and displays rising AIDS incidence and mortality rates and late diagnoses. The data suggest that AIDS cases are hitting mostly young adults and have recently shifted toward men, both homosexual and heterosexual. AIDS cases among the indigenous people have remained stable and low. However, the epidemic has disseminated to the interior of the state, which adds diffi culties to its control, given the geographical isolation, logistical barriers, and culturally and ethnically diverse population. Antiretroviral (ARV) therapy has been decentralized, but peripheral ARV services are still insuffi cient and too distant from people who need them. Recently, the expansion of point-of-care (POC) rapid HIV testing has been contributing to overcoming logistical barriers. Other new POC devices, such as the PIMA CD4 analyzer, will bring the laboratory to the patient. AIDS uniquely coexists with other tropical infections, sharing their epidemiological profi les. The increased demand for HIV/AIDS care services can only be satisfi ed through increased decentralization to peripheral health units, which can also naturally integrate care with other tropical infections and can promote a shift from vertical to integrated programming. Future challenges involve building surveillance data on HIV case notifi cation and covering the spectrum of engagement in care, including adherence to treatment and follow-up loss.

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Section: Future Perspectivesmentioning

confidence: 99%

HIV/AIDS epidemic in the State of Amazonas: characteristics and trends from 2001 to 2012

Oliveira

Benzaken

Saraceni

et al. 2015

Rev. Soc. Bras. Med. Trop.

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“…No entanto outros fatores podem ter importante impacto na redução da mortalidade. Segundo Grangeiro et al (2011), o acesso ao diagnóstico e tratamento no tempo considerado adequado poderia reduzir em até 50% as taxas brasileiras de mortalidade por AIDS.…”

Section: Resultsunclassified

Caracterização dos casos de HIV/AIDS no município de Irati, PR, no período de 1994 a 2012

Santos

Zambenedetti

2016

PSSA

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ResumoA AIDS representa um fenômeno global e bastante complexo, envolvendo aspectos biológicos, psicológicos e sociais. A partir da descoberta do agente causador da AIDS, o HIV, no início da década de 1980, verifi cou-se sua rápida expansão pelo mundo, primeiramente para as grandes metrópoles e, mais tarde, para os municípios de médio e pequeno porte. Ao longo das três últimas décadas, seu perfi l epidemiológico se tornou bastante diversifi cado, de acordo com cada região. Este estudo buscou investigar as características da epidemia da AIDS no município de Irati, PR, no período de 1994 a 2012, levando-se em consideração aspectos como forma de transmissão, faixa etária, proporção homens X mulheres, entre outros. Foi realizada uma pesquisa exploratória, com viés descritivo, através da análise dos prontuários e dados disponíveis no setor de epidemiologia da Secretaria Municipal da Saúde de Irati, PR. A análise realizada contribui para a identifi cação de possíveis condições que apontam para vulnerabilidades específi cas desse contexto, contribuindo para a formulação de intervenções mais contextualizadas. Indica-se a necessidade de estudos com caráter qualitativo, que possam aprofundar a compreensão da vulnerabilidade à AIDS no contexto estudado. Palavras-chave: AIDS; Interiorização; Saúde coletiva; Serviços de saúde. AbstractAIDS is a global and very complex phenomenon, involving biological, psychological and social. From the discovery of the causative agent of AIDS, HIV, in the early 1980s, there was a rapid expansion throughout the world, primarily for large cities and later to the medium and small municipalities. Over the last three decades epidemiological profi le has become quite diverse, according to each region. This study investigated the characteristics of the AIDS epidemic in the city of Irati, PR, in the period 1994-2012, taking into account aspects such as mode of transmission, age, proportion men/women, among others. An exploratory research, with descriptive bias by analyzing the records and data available at the Municipal epidemiology sector of Irati, PR. The analysis contributes to the identifi cation of possible conditions related to specifi c vulnerabilities this context, contributing to the formulation of more contextualized interventions. Indicates the need for qualitative studies, they can deepen the understanding of vulnerability to AIDS in the context studied. Key words: AIDS; Internalization; Public health; Health services. ResumenEl SIDA representa un fenómeno global y bastante complejo, se ha involucrado aspectos biológicos, psicológicos y sociales. Desde el hallazgo del agente causante del SIDA, el VIH, en el inicio de la década de 1980, se verifi có su rápida expansión en todo el mundo, primer sobre las grandes metrópolis y, más tarde, para los municipios de medio y pequeno porte. Durante las últimas tres décadas, su perfi l epidemiológico se ha convertido en bastante diversifi cado, de acuerdo con cada región. Este estúdio buscó investigar las características de la epidemia de la SIDA em...

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“…generally at a late stage and with advanced immunosuppression. 18,19 Failures of post-test counseling to convey the benefits of early medical follow-up, or difficulties in accessing medical care are important factors in the previously described disparity between the time of diagnosis at the VCT and the presentation for medical care in Brazil. 11 There was no great variation in viral subtypes found between recent and chronic infections, with predominance of subtype B followed by subtype F. Differing from the southern region of the country, the frequency of subtype C remained low in both groups (less than 5%).…”

Section: Discussionmentioning

confidence: 99%

Recent HIV infection rates among HIV positive patients seeking voluntary counseling and testing centers in the metropolitan region of Recife - Pe, Brazil

Cavalcanti¹,

Brito²,

Salustiano³

et al. 2012

Braz J Infect Dis

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The highest prevalence was in Recife (3.9%). The prevalence was higher among males (3.93%), and men who have sex with men (MSM) (12.4%). The frequency of recent infections among the 169 subjects evaluated was 23.7%. Recent infections were more common among individuals under 25 years of age. There was slight predominance of men and higher frequency of heterosexuals in both groups, but still a significant portion of MSM (33%). Subtype B predominated, followed by a high proportion of subtype F.Conclusions: Recent infection occurs mainly among young individuals and heterosexuals, despite a significant proportion of recent infection among MSM. These results suggest that preventive actions aimed at the MSM community remains a challenge and efforts focusing this group should continue to be a priority.

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Late Entry into HIV Care: Estimated Impact on AIDS Mortality Rates in Brazil, 2003–2006

Cited by 58 publications

References 41 publications

HIV/AIDS epidemic in the State of Amazonas: characteristics and trends from 2001 to 2012

HIV/AIDS epidemic in the State of Amazonas: characteristics and trends from 2001 to 2012

Caracterização dos casos de HIV/AIDS no município de Irati, PR, no período de 1994 a 2012

Recent HIV infection rates among HIV positive patients seeking voluntary counseling and testing centers in the metropolitan region of Recife - Pe, Brazil

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