Late death after arterial switch operation for transposition of the great arteries

Left-Sided Reoperations After Arterial Switch Operation: A European Multicenter Study

“…The ASO for treating patients with D-TGA and DORV TGA-type is associated with excellent early-and long-term survival and a good quality of life in the vast majority of patients [1][2][3][4][5][6][7]17].…”

Normal Coronary Flow Reserve After Arterial Switch Operation for Transposition of the Great Arteries

“…8 -10 The coronary arteries in children treated with ASO for TGA are surgically relocated to the aortic root, and this may cause coronary flow abnormalities, even late after the operation. 1,2,11 Myocardial perfusion defects found in asymptomatic survivors of the ASO have raised further concerns regarding the long-term function and patency of the coronary arteries in this patient group, recently supported by myocardial PET studies revealing reduced global myocardial CFR. 4,6,12 Documented cases of true myocardial ischemia or sudden death in this patient group have however been exclusively associated with anatomic coronary stenosis.…”

“…4,6,12 Documented cases of true myocardial ischemia or sudden death in this patient group have however been exclusively associated with anatomic coronary stenosis. 11,13 Coronary Flow Velocity at Rest…”

Transposition of the great arteries. Evaluation of the results and current management

“…Mid-term follow-up is greatly influenced by coronary events after the Jatene procedure, as demonstrated in several studies (table III), where coronaryangiographies show them to occur in 3 to 11% of the cases during a 5-year follow-up after the surgery, with a mortality rate ranging from 0 to 10% [2][3][4][5][6] .…”

“…Complications from these pre-existing factors or resulting from the technique itself are mainly represented by ventricular failure, coronary events, right ventricular outflow tract obstruction, and regurgitation of the new aortic valve [2][3][4][5][6][7] .…”