LASMIK laser biorevitalization: mechanisms and therapeutic experience

Abstract

LASMIK laser biorevitalization is a well-known technology developed in Russia that is based on laser phoresis as a method to enhance percutaneous penetration of substances. The article describes the mechanisms that act here and factors that determine the optimal parameters of the technique. The research conducted for 2 years allowed to optimize the parameters of the laser phoresis technique, testing the LASMIK laser biorevitalization technology. Our findings indicate the stimulation of facial skin blood microcirculation and, consequently, an increase in the oxygen tension in the skin, oxygenation of the facial skin blood, and an increase in the trophic support to tissues. The skin becomes 5-15 years younger, a noticeable reduction of facial wrinkles is demonstrated. The studies enabled to optimize the parameters of gels and laser exposure for the maximum efficiency of procedures that are in great demand both by cosmetologists and customers, due to non-invasiveness, simplicity and good results.

Biological Response of Erythrocytes to Laser Irradiation with a Wavelength of 445 nm (An Experimental Study)

“…We have noted a slight but significant increase in the number of deformable forms of erythrocytes. The non-contact exposure of tissues to laser irradiation at low power levels results in a variety of physiological processes at the cellular and tissue levels [35]. Since 2015, the global dental community has adopted the term photobiomodulation (PBM) for this procedure [36].…”

“…This phenomenon has been observed during both the LLLT and PBM procedures [31]. As is widely acknowledged, the fundamental mechanism behind LLLT and PBM is the activation of thermodynamic Ca2+-dependent processes, as a result of which the synthesis of DNA and RNA is enhanced, the synthesis and accumulation of ATP in the mitochondria increases, the release of nitric monoxide increases, while the level of Ca2+ in the Golgi apparatus is maintained due to the work of the Ca2+-ATP enzyme [8,35]. The phenomenon of increasing the energy capacity of cells and the entire body in the process of laser therapy is of key importance, since there is an elimination of chronic energy deficiency inherent in the sick body and the appearance of free energy necessary to start processes aimed at healing [42].…”

Protocol for a Single-Arm Feasibility Study of Photobiomodulation for Fatigue, Depression, and Pain in Inflammatory Bowel Disease

“…Sensitivity to light has been reported in 2-15% of PBM trials participants, in the form of temporary dizziness, increase in pain, tiredness, or euphoria. Several studies have concluded that there are no long-term adverse effects of PBM in vitro [28], in vivo, including non-human primates [29], and in human models [30][31][32]. We therefore do not expect the participants to experience any adverse events.…”