Laser treatment of acne conglobatа with concomitant oral isotretinoin use

Kalashnikova, Natalia; Albanova, V. I.; Jafferany, Mohammad

doi:10.1111/dth.14553

Cited by 4 publications

(2 citation statements)

References 9 publications

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“…Поглощение такого излучения вызывает появление очагов поверхностной микроабляции и мощные акустические резонансные волны, распространяющиеся в глубокие слои кожи. Локальное увеличение мощности акустических волн за счет их интерференции оказывает микротравмирующее действие на мембраны и коллагеновые волокна, стимулируя репаративные процессы и ремоделирование рубцовой ткани [16][17][18][19][20]. В зависимости от длительности импульса глубина реализации эффекта может быть от 3 до 6 мм (доступны поверхностный и глубокий режимы), что позволяет оказывать воздействие на уровне кожи и подкожных тканей в зависимости от глубины локализации патологического очага.…”

Section: материал и методыunclassified

Early laser treatment of local complications after surgical blepharoplasty

Kalashnikova¹,

Kochetova

Пахомова

2023

ВХ

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Purpose of the study: to evaluate the effectiveness of early laser treatment of various types of local complications after surgical blepharoplasty based on the dynamics of the clinical picture and outcome, as well as patient satisfaction indicators according to FACE-Q.Material and methods. The study involved 24 patients with various types of local postoperative complications: scars with a tendency to hypertrophic growth (5 cases), inversion of the lower eyelid (4), seroma with undetected ligature fragments (2), aseptic inflammation of soft tissues of unknown genesis (2), neoangiogenesis in the eyelid area (3), extensive hemorrhages in the surgical intervention area (8 cases). Treatment was started on the day of the patient's treatment when the fact of the complication was established. The treatment was performed using the MultilineTM laser multiplatform using the Nd:YAP/KTP vascular laser with a combination of two wavelengths of 540 and 1079 nm and/or the Er:YAG, 2940 nm laser with SMA technology. The choice of the type of laser radiation and the interval between sessions were determined by the nature of the complication. Patients' satisfaction with the results of treatment was determined by the FACE-Q questionnaire.Results. The results of treatment by evaluators were determined as excellent in 19 patients (79.2%) and good in 5 patients (20.8%). The outcome of the resolution of complications in all patients was a thin, flat, inconspicuous scar, persistent defects requiring additional correction were not observed. During 6 months of follow-up, the dynamics of FACE-Q indicators after laser treatment of complications showed a statistically significant improvement on all assessed scales: the general appearance of the eye, the outcome of the operation performed, the severity of side effects, psychological stress, social adaptation.Conclusion. Laser treatment of postoperative complications of blepharoplasty allows improving the aesthetic result of the operation and restoring the psychoemotional state of the patient.

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Section: материал и методыunclassified

Early laser treatment of local complications after surgical blepharoplasty

Kalashnikova¹,

Kochetova

Пахомова

2023

ВХ

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“…Acne commonly occurs on adolescents' faces, neck, forehead, and back. Severe acne may lead to scarring, with an incidence of nearly 20 % in adolescents, greatly impacting patients, physically and psychologically [3]. A questionnaire survey [4,5] revealed that 33 % of 4,618 acne patients had facial scars, and followup interviews showed that these patients were perceived as being less attractive and less confident, and more introverted, shy, and insecure than those with normal skin.…”

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confidence: 99%

Therapeutic effect of the combination of fractional laser and recombinant bovine basic fibroblast growth factor in acne scar patients

Wu,

Gao,

Bai

2024

Trop. J. Pharm Res

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Purpose: To assess the feasibility and safety of a combination therapy involving fractional laser treatment and recombinant bovine basic fibroblast growth factor (rb-bFGF) in acne scar patients.Methods: 90 patients with acne scar admitted at Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology from September 2020 to December 2022 were enrolled in retrospective study. Patients were divided into control group (n = 41), treated with rb-bFGF alone and study group (n = 49), which underwent fractional laser treatment using Lutronic fractional laser device involving 40 days per session for three sessions, with additional application of rb-bFGF in the affected area at a dose of 300 IU/cm2 , three times daily, for seven consecutive days following the completion of each laser treatment session. Treatment effect, skin physiological indices, lactic acid stinging test (LAST) scores, stratum corneum integrity, and incidence of adverse reactions were determined.Results: Study group demonstrated superior efficacy with a total effectiveness of 97.96 %, significantly outperforming control group at 85.3 % (p < 0.05). Pre-treatment, both groups exhibited comparable values in trans-epidermal water loss (TEWL), pH, stratum corneum hydration, and erythema (a-value) (p> 0.05). Post-treatment, both groups exhibited significant improvements, with reduced TEWL, pH, and a-value, along with increased stratum corneum hydration (p < 0.05). Compared to control group, study group showed significantly lower TEWL, pH, and a-value, coupled with higher stratum corneum hydration (p < 0.05). Post-treatment, study group demonstrated lower total LAST scores, improved stratum corneum integrity, and a significantly lower incidence of adverse reactions.Conclusion: The combination of fractional laser and rb-bFGF in patients with acne scar improves skin barrier function, reduces lactic acid-induced stinging, and enhances stratum corneum integrity. Further research and clinical trials are needed to optimize the treatment protocols.

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Efficacy and safety of low-level light therapy by delicate pulsed light combined with low-dose oral isotretinoin for the treatment of acne vulgaris: a randomized split-face study

Xia

Zhu

et al. 2022

Lasers Med Sci

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Laser treatment of acne conglobatа with concomitant oral isotretinoin use

Cited by 4 publications

References 9 publications

Early laser treatment of local complications after surgical blepharoplasty

Early laser treatment of local complications after surgical blepharoplasty

Therapeutic effect of the combination of fractional laser and recombinant bovine basic fibroblast growth factor in acne scar patients

Efficacy and safety of low-level light therapy by delicate pulsed light combined with low-dose oral isotretinoin for the treatment of acne vulgaris: a randomized split-face study

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