Laser Tissue Welding

McNally-Heintzelman, Karen M.; Welch, Ashley J.

doi:10.1201/9780203008997.ch39

Cited by 28 publications

(24 citation statements)

References 189 publications

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“…The liquid albumin solder alone did not provide sufficient bond strength, but the addition of solid albumin strips increased the bond strength significantly. These results, and other experiments of laser soldering in other organs [4,5] , suggest that this technique is an effective alternative for tissue bonding.…”

Section: Introductionmentioning

confidence: 60%

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ICG-dyed albumin and diode laser heating for soldering of the trachea

et al. 2006

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Laser tissue soldering is a technique for the closure of incisions, which provides an immediate air-and watertight bond. Previous studies have shown that this method can bond tracheal incisions with the aid of stay sutures or solid albumin strips. In this study we investigated whether soldering using a diode laser and indocyanine green (ICG) dyed liquid albumin solution as solder, was efficacious for the repair of tracheal incisions without the need for additional strengthening aids. A transverse incision was made in isolated pig tracheas. The incision was smeared with liquid solder composed of 42% bovine albumin and 0.1 mg/ml ICG, and soldered using a temperature-controlled fiberoptic diode laser system. The soldered tracheal ends were sealed and the burst pressure measured. In a series of experiments the burst pressure was found to be higher than 382 mm Hg. These preliminary results demonstrate that diode laser tissue soldering of tracheal incisions provides better results than with a CO2 laser, and that it is possible to achieve considerable soldering strength without the use of any additional strengthening procedures.

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Section: Introductionmentioning

confidence: 60%

“…It is believed that the energy generated in the laser heated tissue causes changes in the structure of collagen and elastin that lead to interlacing of the fibers [5] . Chemical cross-linking between other matrix proteins has also been found following laser heating [9] .…”

Section: Discussionmentioning

confidence: 99%

ICG-dyed albumin and diode laser heating for soldering of the trachea

et al. 2006

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“…Efforts have been directed at reducing surgical time and at developing non-suture 3 and nonocclusive methods 4,5 of vascular anastomosis. Laser-induced suturing based on vascular welding could offer significant advantages, such as simplification of the surgical procedure, reduction of bleeding, better re-endothelization of the vascular segments 6 . In past years, vascular welding had been obtained experimentally with Nd:YAG, argon and CO2 lasers.…”

Section: Introductionmentioning

confidence: 99%

An experimental study on laser-induced suturing of venous grafts in cerebral revascularization surgery

et al. 2005

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To test laser-assisted high flow bypass in cerebral revascularization procedures, we set up an experimental model on rabbits which included harvesting a jugular vein graft and its implantation on the common carotid artery through a double end-to-side anastomosis. The study was carried out on 25 New Zealand rabbits by performing on each animal the proximal anastomosis using conventional suturing, while the distal one was obtained by means of low-power diode laser welding in association with the topical application of Indocyanine Green (ICG) solution to enhance local absorption of the laser light. After the procedure, the animals were subjected to a follow-up from 2 to 9 days. Bypass patency was evaluated by means of Doppler study. The vascular segments were excised and evaluated by histological and immunohistochemical examinations. Utilization of the diode laser was associated with a substantial shortening of the operative time, as well as with a more active endothelial regeneration process at the anastomotic site.

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“…It has been proposed as an alternative technique or adjunct to conventional suturing procedures to reduce the typical inflammatory processes, such as foreign-body reaction after the application of sutures, as well as to facilitate suturing under certain surgical conditions. 10,11 Many reports of laser-assisted welding techniques mention the possibility of performing effective tissue closure with minimum side effects and improving the healing process. In ophthalmology, experimental studies of laser-induced sealing of corneal tissue in animal models, based on direct absorption of near-infrared and farinfrared laser light by the water content of the cornea, have been reported since 1992.…”

mentioning

confidence: 99%