Laser therapy for breast cancer: MR imaging and histopathologic correlation.

Mumtaz, Hamid; Hall-Craggs, M. A.; Wotherspoon, Andrew; Paley, M; Buonaccorsi, Giovanni A.; Amin, Zahir; Wilkinson, Ian B.; Kissin, Mark; Davidson, T.; Taylor, I.; Bown, Stephen G.

doi:10.1148/radiology.200.3.8756910

Cited by 149 publications

(84 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A total of 63 articles matched the selection criteria. The 63 articles included 16 feasibility studies [13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28], 12 phase I studies [29][30][31][32][33][34][35][36][37][38][39][40], nine phase II studies [41][42][43][44][45][46][47][48][49], three comparative studies [50][51][52], one retrospective study [53], and four randomised controlled trials [54][55][56]. In 18 studies the type of study was not reported [8,[57][58][59][60][61][62][63][64]…”

Section: Selected Studiesmentioning

confidence: 99%

“…The ablation process involves two phases: freezing and thawing with four mechanisms destroying the tumour cells: direct damage by intracellular ice formation and osmotic dehydration and indirect damage due to ischemia and immunologic response. [36,78] Seven studies used laser-ablation (231 patients) [18,28,33,34,50,62,63], in which lesions are ablated due to direct heating with low-power laser light energy delivered percutaneously via thin optical fibres. Upon absorption in the tissue, heat is produced, inducing lethal thermal injury.…”

Section: Study Characteristicsmentioning

confidence: 99%

See 1 more Smart Citation

Minimally invasive ablative techniques in the treatment of breast cancer: a systematic review and meta-analysis

Peek

Ahmed

Napoli

et al. 2016

International Journal of Hyperthermia

View full text Add to dashboard Cite

Purpose: Breast conserving surgery is effective for breast cancer treatment but is associated with morbidity in particular high re-excision rates. We performed a systematic review to assess the current evidence for clinical outcomes with minimally invasive ablative techniques in the non-surgical treatment of breast cancer.Methods: A systematic search of the literature was performed using PubMed and Medline library databases to identify all studies published between 1994 and May 2016. Studies were considered eligible for inclusion if they evaluated the role of ablative techniques in the treatment of breast cancer and included ten patients or more. Studies that failed to fulfil the inclusion criteria were excluded. Results:We identified 63 studies including 1608 patients whose breast tumours were treated with radiofrequency (RFA), high intensity focused ultrasound (HIFU), cryo-, laser or microwave ablation. Fifty studies reported on the number of patients with complete ablation as found on histopathology and the highest rate of complete ablation was achieved with RFA (87.1%, 491/564) and microwave ablation (83.2%, 89/107). Short-term complications were most often reported with microwave ablation (14.6%, 21/144). Recurrence was reported in 24 patients (4.2%, 24/570) and most often with laser ablation (10.7%, 11/103). The shortest treatment times were observed with RFA (15.6±5.6 minutes) and the longest with HIFU (101.5±46.6 minutes).

show abstract

Section: Selected Studiesmentioning

confidence: 99%

Section: Study Characteristicsmentioning

confidence: 99%

Minimally invasive ablative techniques in the treatment of breast cancer: a systematic review and meta-analysis

Peek

Ahmed

Napoli

et al. 2016

International Journal of Hyperthermia

View full text Add to dashboard Cite

show abstract

“…[36][37][38] The light is both scattered and absorbed by the tissue. The absorption events are primarily near the laser and result in large heating near the laser applicator.…”

Section: Laser Ablationmentioning

confidence: 99%

Image-Guided Ablation in Breast Cancer Treatment

Roubidoux

Yang

Stafford

2014

Techniques in Vascular and Interventional Radiology

View full text Add to dashboard Cite

“…Laser ablation for the treatment of early-stage breast cancer has not been studied extensively, but some have shown that small tumors can be ablated with negative margins [41,42]. Harms et al [42] treated 12 breast cancer patients by using rotating delivery of excitation off-resonance under MRI guidance.…”

Section: Laser Ablationmentioning

confidence: 99%

Minimally Invasive Approaches for Diagnosis and Treatment of Early-Stage Breast Cancer

Vlastos

Verkooijen

2007

The Oncologist

View full text Add to dashboard Cite

LEARNING OBJECTIVESAfter completing this course, the reader will be able to:1. Describe the minimally invasive approaches to breast cancer diagnosis and treatment.2. List the strengths and weaknesses of minimally invasive diagnostic and treatment procedures.3. Select appropriate patients for minimally invasive approaches to breast cancer diagnosis and treatment.Access and take the CME test online and receive 1 AMA PRA Category 1 Credit ™ at CME.TheOncologist.com CME CME ABSTRACTBreast cancer management has been evolving toward minimally invasive approaches. Image-guided percutaneous biopsy techniques provide accurate histologic diagnosis without the need for surgical biopsy. Breast conservation therapy has become the treatment standard for earlystage breast cancer. Sentinel lymph node biopsy is a new procedure that can predict axillary lymph node status without the need of axillary lymph node dissection. The next challenge is to treat primary tumors without surgery. For this purpose, several new minimally invasive procedures, including radiofrequency ablation, interstitial laser ablation, focused ultrasound ablation, and cryotherapy, are currently under development and may offer effective tumor management and provide treatment options that are psychologically and cosmetically more acceptable to the patients than are traditional surgical therapies. In this review, we give an overview of minimally invasive approaches for the diagnostic and therapeutic management of early-stage breast cancer. The Oncologist 2007;12: [1][2][3][4][5][6][7][8][9][10]

show abstract

Laser therapy for breast cancer: MR imaging and histopathologic correlation.

Abstract: Delayed gadolinium-enhanced MR images can help define the extent of laser-induced necrosis and residual tumor after interstitial laser photocoagulation therapy in breast cancer.

Cited by 149 publications

References 0 publications

Minimally invasive ablative techniques in the treatment of breast cancer: a systematic review and meta-analysis

Minimally invasive ablative techniques in the treatment of breast cancer: a systematic review and meta-analysis

Image-Guided Ablation in Breast Cancer Treatment

Minimally Invasive Approaches for Diagnosis and Treatment of Early-Stage Breast Cancer

Contact Info

Product

Resources

About