“…A paradigm shift has been seen in the last years in the target morphology, from simple flat foils to micro-and nano-structured targets presented in several reports, in order to highlight the benefit of the latests. Targets consisting of nanowires [88], micropillars and microtubes [51,72,89], nanochannels [59], nanoholes [90], flat foils embedded with nanoparticles [91] or with nanospheres [66,69,92], double layers made of different materials [38,93], a combination of double-layer and embedded nanospheres [67], foams [94][95][96] and flat foil with grooves or micro-gratings [28,69,97,98] have already been tested. The results reported with these types of targets are presented also in Figure 4.…”