Laser‐assisted subepithelial keratectomy <i>versus</i> epipolis laser in situ keratomileusis for myopia: a meta‐analysis of clinical outcomes

Wen, Daizong; Huang, Jinhai; Li, Xuexi; Savini, Giacomo; Feng, Yifan; Qiu, Lin; Wang, Qinmei

doi:10.1111/ceo.12205

Cited by 8 publications

(8 citation statements)

References 55 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[21] However, most studies failed to show any differences between LASEK and epi-LASIK in safety, efficacy, epithelial healing time, and corneal haze formation. [14,22,23] On the other hand, one previous study suggested LASEK provided faster visual rehabilitation and had better safety and efficacy than epi-LASIK at 3 months after operation. [24] …”

Section: Discussionmentioning

confidence: 99%

Predictability and stability of laser-assisted subepithelial keratectomy with mitomycin C for the correction of high myopia

Fan

Chen

et al. 2017

Medicine

View full text Add to dashboard Cite

The purpose of this study was to evaluate the predictability and stability of laser-assisted subepithelial keratectomy (LASEK) with mitomycin C (MMC) in correction of high myopia (≤−6.0 diopters [D]) as compared to low-to-moderate myopia (>−6.0 D).This is a retrospective, comparative, cohort study which included 43 eyes of 43 consecutive patients who underwent LASEK with MMC in a private hospital in Hong Kong by a single surgeon. Twenty-five eyes had high myopia (mean spherical equivalent [SE] = −8.53 ± 1.82 D) and 18 eyes had low-to-moderate myopia (mean SE = −3.99 ± 1.37 D) before surgery.In terms of refractive predictability, mean SE was significantly better in eyes with preoperative low-to-moderate myopia than high myopia at 6 months (0.04 ± 0.23 vs 0.31 ± 0.52 D, P = .035). In terms of refractive stability, between 1 and 3 months, both groups had mean absolute change of SE of around 0.25 D. Between 3 and 6 months, preoperative low-to-moderate myopia group had significantly less absolute change of SE compared to high myopia group (0.07 vs 0.23 D, P = .003). More eyes with preoperative high myopia changed SE by more than 0.25 D than those with low-to-moderate myopia between 3 and 6 months (32.0% vs 5.6%, P = .057).In conclusion, LASEK with MMC is more unpredictable and unstable in correction of high myopia than low-to-moderate myopia. The refractive outcome of most low-to-moderate myopia correction stabilizes at 3 months. Stability is not achieved until after 6 months in high myopia correction.

show abstract

Section: Discussionmentioning

confidence: 99%

Predictability and stability of laser-assisted subepithelial keratectomy with mitomycin C for the correction of high myopia

Fan

Chen

et al. 2017

Medicine

View full text Add to dashboard Cite

show abstract

“…48 A recent meta-analysis comparing LASEK and conventional PRK 49 concluded that uncertainty surrounds differences in efficacy, accuracy, safety and adverse effects between LASEK and PRK for eyes with low to moderate myopia. A similar conclusion was reached and published in 2010.…”

Section: Laser Ablation Algorithmsmentioning

confidence: 99%

Surface Ablation Techniques for Myopia – A Review of the Advances Over the Past 25 Years

Hjortdal¹

2017

European Ophthalmic Review

View full text Add to dashboard Cite

Photorefractive keratectomy for correction of myopia was the first excimer laser-based technique to be developed. During the last 25 years, excimer lasers have improved technologically, several variations of the technique have been developed and pre-and postoperative pharmaceutical therapies have been investigated. This review article summarises these developments and the published meta-analyses on comparison of surface ablation techniques and laser in situ keratomileusis. The main conclusion is that there seem to be no differences between the clinical results obtained with the different variations of surface ablation techniques. KeywordsPhotorefractive keratectomy, laser in situ keratomileusis (LASIK), refractive surgical procedures, myopia, excimer laser Disclosure: Jesper Hjortdal discloses that Aarhus University Hospital has signed a research support agreement with Carl Zeiss Meditec, Jena Germany. No funding was received in the publication of this article. This study involves a review of the literature and did not involve any studies with human or animal subjects performed by any of the authors.Authorship: All named authors meet the International Committee of Medical Journal Editors (ICMJE) criteria for authorship of this manuscript, take responsibility for the integrity of the work as a whole, and have given final approval to the version to be published.Open Access: This article is published under the Creative Commons Attribution Noncommercial License, which permits any non-commercial use, distribution, adaptation and reproduction provided the original author(s) and source are given appropriate credit. When such a gas is put under electrical stimulation and high pressure, the excited compound can give up its excess energy by undergoing spontaneous emission, which very quickly (on the order of a picosecond) dissociates back into two unbound atoms. Directing the emitted light towards, for example, biological materials will result in ablation of surface molecules. In the early 1980s it was shown that using this approach biological materials, including the cornea, could be incised using the excimer laser.1-3 After short time, it was realised that actual surface ablation of the corneal stroma was possible after removal of the corneal epithelium 4 and that the resulting surface was very smooth. 5 In 1987, excimer laser-based keratotomy was performed in a human eye, 6 but it was the surface ablation application that pushed development of excimer lasers. 7,8 The first preliminary results in human eyes were published the late 1980s 9-12 and excimer lasers became commercially available around 1990. In the early 1990s larger follow-up series of patients undergoing PRK for myopia were published. [13][14][15] Since then, many modifications of PRK have been introduced, and a common uniting name for all these techniques is 'surface ablation'. This review will focus on surface ablation for myopia. Development of excimer lasersDirecting the location of the excimer laser rays is essential to change the surface shape of the ...

show abstract

“…Meta-analyses do 'avoid the narrative of the literature review'; however, they still require a qualitative narrative for explanations of similarities and differences found among studies and this is beyond the realm of ordinary statistics. 6 Statistics are important, but whether in analysis of basic data, or as part of meta-analysis, 'statistics serve as fallible pattern recognition devices; explanation of the origin of the observed patterns is beyond the scope of these devices'. 6 5.…”

Section: Looking Deeper Than (Just) Below the Surfacementioning

confidence: 99%

Looking deeper than (just) below the surface

Thomas

Mengersen

Thomas

et al. 2014

Clinical Exper Ophthalmology

View full text Add to dashboard Cite

Laser‐assisted subepithelial keratectomy versus epipolis laser in situ keratomileusis for myopia: a meta‐analysis of clinical outcomes

Cited by 8 publications

References 55 publications

Predictability and stability of laser-assisted subepithelial keratectomy with mitomycin C for the correction of high myopia

Predictability and stability of laser-assisted subepithelial keratectomy with mitomycin C for the correction of high myopia

Surface Ablation Techniques for Myopia – A Review of the Advances Over the Past 25 Years

Looking deeper than (just) below the surface

Contact Info

Product

Resources

About