Laser Ablation/Inductively Coupled Plasma Mass Spectrometry with Aerosol Density Normalization

Tanaka, Tomonari; Yamamoto, Kazushi; Nomizu, Tsutomu; Kawaguchi, Hiroshi

doi:10.2116/analsci.11.967

Cited by 17 publications

(10 citation statements)

References 7 publications

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“…Measurement of light scattered by ablated particles moving through an optical cell may also be used to determine the ablated mass, 37 and has shown precision comparable to the use of IS elements. 38,39 This method shows the most potential for use in imaging, where the signal obtained from light scattering could be measured and used to normalise the corresponding transient signal recorded by the ICP-MS, provided the time required for particles to pass from the optical cell to detector is known. This time interval must be precisely measured, and would benefit from the use of ultra-short femtosecond (fs) laser instruments.…”

Section: Internal Standardisation and Independent Measurement Of Abla...mentioning

confidence: 99%

Quantification strategies for elemental imaging of biological samples using laser ablation-inductively coupled plasma-mass spectrometry

Hare

Austin

Doble

2012

Analyst

155

117

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This review provides analysts with critical insights of current approaches for quantification by laser ablation-inductively coupled plasma-mass spectrometry in the field of elemental imaging. This encompasses both calibration strategies that have been used with success in imaging biological samples, as well as those with potential to improve analytical accuracy and precision if applied to imaging. Methods reviewed include the use of CRMs, laboratory prepared matrix matched standards, internal standardisation, online standard addition and a variety of novel approaches that makes elemental imaging accessible to a wider base of analysts. The importance of quantification and factors affecting its use in imaging will also be considered.

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Section: Internal Standardisation and Independent Measurement Of Abla...mentioning

confidence: 99%

Quantification strategies for elemental imaging of biological samples using laser ablation-inductively coupled plasma-mass spectrometry

Hare

Austin

Doble

2012

Analyst

155

117

View full text Add to dashboard Cite

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“…In addition, the light scattering produced by the transported ablation aerosols was instrumental in normalizing the ICP signals [6]. Information on the variations of aerosol densities and particle size distribution has allowed for improvement of LA-ICP analysis [7,8]. Therefore, considerable investigative efforts have recently been devoted to providing detailed information on laser-generated plasma [3,9,10,11].…”

Section: Introductionmentioning

confidence: 99%

Study of the morphology of a laser-produced aerosol plume by cavity ringdown laser absorption spectroscopy

2003

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Cavity ring-down laser absorption spectroscopy (CRLAS) was applied for the first time to detection and characterization of laser breakdown generated aerosols. The method provided time-resolved morphological information on the aerosol plume, which is of importance in laser ablation (LA) and deposition, in laser-induced breakdown spectroscopy (LIBS) analysis, and in laser ablation inductively coupled plasma (LA-ICP) methods. This method provides sensitive detection of a variety of aerosols produced under ambient conditions. The morphological investigation revealed that the aerosol density has a reproducible pattern as a function of distance from the surface, although its details depend on time, on geometrical parameters and on the surface characteristics.

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“…ICP-AES and ICP-MS have also been applied to real-time analysis of chemical compositions of aerosol particles (Nomizu et al 1992(Nomizu et al , 1993Kaneco et al 1995;Tanaka et al 1995). Aerosol is diluted by excess argon and then introduced directly into an argon plasma torch of ICP-AES or ICP-MS.…”

Section: Introductionmentioning

confidence: 99%

DMA as a Gas Converter from Aerosol to "Argonsol" for Real-Time Chemical Analysis Using ICP-MS

Myojo

Takaya

Ono-Ogasawara

2002

Aerosol Science and Technology

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In this study, "Argonsol" is de ned as an assembly of liquid or solid particles suspended in argon, just as an aerosol is a suspension in air. Argonsol can be generated by a nebulizer and fed into a plasma torch for measurement by inductively coupled plasma atomic emission spectrometry (ICP-AES) and inductively coupled plasma mass spectrometry (ICP-MS). We have developed a new gas-conversion method, by means of a DMA, from normal aerosol to size-classi ed Argonsol for a chemical analysis using ICP-MS. A test aerosol containing lead as a typical toxic heavy metal was introduced into this system. With this system the size-related elemental concentration of lead nitrate particles in the range of 30 to 140 nm was measured. The sensitivity of this system is better than fg (10 ¡ 15 g) of lead in the total mass of particles introduced into ICP-MS. In principle, it is possible for our system to analyze all the elements that ICP-MS and/or ICP-AES can analyze.

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Laser Ablation/Inductively Coupled Plasma Mass Spectrometry with Aerosol Density Normalization

Cited by 17 publications

References 7 publications

Quantification strategies for elemental imaging of biological samples using laser ablation-inductively coupled plasma-mass spectrometry

Quantification strategies for elemental imaging of biological samples using laser ablation-inductively coupled plasma-mass spectrometry

Study of the morphology of a laser-produced aerosol plume by cavity ringdown laser absorption spectroscopy

DMA as a Gas Converter from Aerosol to "Argonsol" for Real-Time Chemical Analysis Using ICP-MS

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