Laryngeal Tuberculosis: A Report of 15 Cases

Nishiike, Suetaka; Irifune, Morihiro; Doi, Katsume; Sawada, Toru; Kubo, Takeshi

doi:10.1177/000348940211101010

Cited by 53 publications

(39 citation statements)

References 9 publications

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“…8,10 Various studies in the past had stated that mycobacterium tuberculosis usually involves the posterior part of the larynx with lesions usually found to involve the interarytenoid region, the arytenoids and the posterior glottis and was believed to be due to pooling of infected sputum in the recumbent position. 5,8,10 In our study however we found the vocal cords (diffuse) to be the most common site of involvement which was similar to the findings of Shin et al and Clery et al 8,12 Based on macroscopic appearance, Shin et al classified their fibreoptic findings into ulcerofungative mass lesion, whitish ulcerative lesion, nonspecific inflammatory lesion and polypoid lesion and found that ulcerative lesions were the commonest (40.9%) in their study. In our study we observed that both in single and multiple lesions in the larynx, ulcerative lesions was the most common finding.…”

Section: Discussionsupporting

confidence: 90%

“…These finding are similar to other studies which documented ages ranging in the fourth and fifth decade of life. 5,8 Hoarseness of voice was found to be the most common symptom which was found in fourteen (93%) cases. This finding is similar to that of other studies.…”

Section: Discussionmentioning

confidence: 99%

“…3 Nowadays, the presentation of laryngeal tuberculosis without pulmonary tuberculosis is on the rise. 5 The presentation is usually with hoarseness, dysphagia and odynophagia. 6,7 In tuberculosis, the lesions heal by fibrosis.…”

Section: Introductionmentioning

confidence: 99%

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Present scenario of laryngeal tuberculosis

Saldanha¹,

Sima

Bhat³

et al. 2017

Int J Otorhinolaryngol Head Neck Surg

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Background: The objectives of the study were to document the presentation of laryngeal tuberculosis, response to anti-tubercular treatment and objective evaluation of larynx during and post anti-tubercular treatment.Methods: A before and after treatment study including 15 subjects with laryngeal tuberculosis treated in our tertiary health care centre during a three year study period. Clinical presentation, management, subjective self-assessment of voice and objective assessment of larynx by videostroboscopy at the beginning, at two months and at six months of anti-tubercular treatment were documented. Results: Two patients had primary laryngeal tuberculosis and thirteen patients had laryngeal tuberculosis associated with pulmonary tuberculosis. Only one patient was immuno-compromised. Most common presenting symptom was hoarseness (93%). Ulcerative lesions were the most common clinical finding (87%) with the vocal cords being the commonest site involved (80%). All patients responded well to anti-tubercular treatment. Videostroboscopy showed an improvement in vocal cord lesions during treatment. Subjective assessment of voice after two months of anti-tubercular treatment showed marked improvement in voice. At completion of treatment, voice was better but all patients had complaints of residual hoarseness.Conclusions: Primary laryngeal tuberculosis is less common in comparison to laryngeal tuberculosis secondary to pulmonary tuberculosis. With early diagnosis, the response to treatment is satisfactory. Videostroboscopy can be used as an effective tool in monitoring vocal cord changes during the follow- up period.

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Section: Discussionsupporting

confidence: 90%

Section: Discussionmentioning

confidence: 99%

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Present scenario of laryngeal tuberculosis

Saldanha¹,

Sima

Bhat³

et al. 2017

Int J Otorhinolaryngol Head Neck Surg

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“…Larengeal tüberküloz, 5. ve 6. dekadlarda ve erkeklerde (E/K=2/1) daha sık görülmektedir [8]. Hemen her zaman aktif akciğer tüberkülozu ile birliktedir [3].…”

Section: Discussionunclassified

Larenks karsinomunu taklit eden bir olgu: Larenks tüberkülozu

Gül¹,

Bakır²,

Kınış³

et al. 2013

CMJ

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Larenks tüberkülozu, larenksin en sık granülomatöz enflamasyonudur. Hemen daima akciğer tüberkülozu ile beraberdir. Semptomların benzerliği ve kitlenin görünümü nedeniyle larenks maligniteleri ile karışabilir. Akciğer grafisi ve balgam kültürleri yararlı olsa da kesin tanı biyopsi ile konur. Günümüzde larenks tüberkülozu sıklığı azalmakla beraber, hala larenksin en sık granülomatöz hastalığı olmaya devam etmektedir. Ülkemiz gibi tüberkülozun hala ciddi bir sorun oluşturduğu gelişmekte olan ülkelerde, larengeal kitlelerin ayırıcı tanısında akılda tutulmalıdır. Bu yazıda larenks tüberkülozlu bir olgu sunulmuştur. Anahtar sözcükler: Tüberküloz, larenks, larenks tüberkülozu AbstractLaryngeal tuberculosis is the most common granulomatous inflammation of the larynx. It is almost always associated with pulmonary tuberculosis. It may be confused with laryngeal malignancies due to similarity of symptoms and mass appereance. Pulmonary X-ray and positive sputum cultures contribute to the diagnosis but definitive diagnosis of the laryngeal tuberculosis is based on histopathologic findings of the biopsy specimen. Although laryngeal tuberculosis incidence declines, it is still the most common granulomatous inflammation of the larynx. It should be considered in differential diagnosis of laryngeal masses especially in developing countries like our country, which tuberculosis disease is stil common. In this article, a case of larynx tuberculosis is presented. Keywords GirişTüberküloz larenjit, antitüberküloz tedavisinden önceki dönemlere göre sıklığı önemli oranda azalmış olmakla beraber, günümüzde hala larenksin en sık granülomatöz hastalığıdır [1]. Her ne kadar sıklığı %0,6 ile %1,3 olarak bildirilse de bu rakamların gerçeği tam olarak yansıtmadığı düşünülmektedir [2,3]. Çünkü akciğer tüberkülozu tanılı olgularda ses kısıklığı gibi larengeal semptomlar olsa bile, tedavi protokolünü değiştirmeyeceği ve bulaşıcılık riskinin yüksek olduğu düşünüldüğünden, larenksin endoskopik bakısı ihmal edilmektedir. Sonuçta larenks tüberkülozlu olgular gözden kaçabilmektedir [3]. Oysaki postmortem akciğer tüberkülozlu olguların otopsi değerlendirmelerinde %30 oranında larenks tüberkülozu tespit edilmiştir [4]. Ayrıca gelişmiş ülkelerde ciddi bir sorun oluşturan HIV infeksiyonlu olgularda larinks tüberkülozu %5,5 oranında bildirilmektedir [5]. Dünya sağlık örgütünün 2010'da yayınladığı raporda; tüberküloz hastalığının dünya için halen çok ciddi bir sorun olduğunu vurgulamaktadır. Bu raporda; özellikle Asya kıtasını etkileyen bu olgunun yaygınlığının hızla artması yanında, bu hastaların dörtte birinin klasik tüberküloz

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“…Earlier, it affected posterior larynx in most patients, since it directly spreads along the airway [1][2][3][4][5][6]. Currently, however, it is prevalent in all parts of the larynx and is usually seen in people in their 40s-60s as primary laryngeal tuberculosis.…”

Section: Introductionmentioning

confidence: 99%

Primary laryngeal tuberculosis-“The great masquerader”

Sakthivel¹,

Singh²,

Sharma³

et al. 2017

Clin Case Rep Rev

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We report a case of primary laryngeal tuberculosis in a 54 year old Indian male, who had hoarseness as his presenting complaint. This case highlights that laryngeal tuberculosis may occur even without pulmonary tuberculosis, and the characteristics of the lesions now appear to be more nonspecific than earlier. Otolaryngologists and airway physicians need to be more alert to the emergence of laryngeal tuberculosis with atypical clinical manifestations and consider it in their differential diagnosis of all laryngeal diseases.

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Laryngeal Tuberculosis: A Report of 15 Cases

Cited by 53 publications

References 9 publications

Present scenario of laryngeal tuberculosis

Present scenario of laryngeal tuberculosis

Larenks karsinomunu taklit eden bir olgu: Larenks tüberkülozu

Primary laryngeal tuberculosis-“The great masquerader”

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