Laryngeal schwannoma in an 8‐year‐old boy with inspiratory dyspnea

Abstract

Complete removal of laryngeal schwannomas is curative, and adjuvant treatment is not required.

Epiglottic Schwannoma: A Case Report

“…Other benign laryngeal lesions include hamartomas, choristomas, teratomas, lymphangiomas, and juvenile xanthogranulomas, adenoma, laryngeal cysts, internal laryngocele. In our case epiglottic cyst was major differential [3].…”

“…Laryngeal schwannomas are usually isolated, although they have rarely been described in both type 1 and type 2 neurofibromatosis [3].…”

“…They usually involve the supraglottic larynx and may have an insidious clinical course. The most common nerve of origin for of laryngeal schwannoma is medial ramifica- tions of the internal branch of the superior laryngeal nerve [3]. The tumor mainly involves the aryepiglottic folds (80%), the vestibular folds (20%), or extends to the pyriform fossa, whereas the subglottic region is uncommonly involved.…”

“…The tumor mainly involves the aryepiglottic folds (80%), the vestibular folds (20%), or extends to the pyriform fossa, whereas the subglottic region is uncommonly involved. Involvement of the true vocal cords is extremely rare [3] [4]. Laryngeal schwannomas may approach a large size, causing upper airway obstruction, dysphonia and even vocal cord fixation, depending on their location [5].…”

“…A portion of the tumor usually has cells with an interlacing, fascicular pattern while in other areas, there is palisading [4]. They show positive immunohistochemistry (IHC) for S-100 protein, but negative for smooth muscle actin, CD 34, and vimentin [3].…”